dbPTM

CLPB_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CLPB_MOUSE
UniProt AC	Q60649
Protein Name	Caseinolytic peptidase B protein homolog
Gene Name	Clpb
Organism	Mus musculus (Mouse).
Sequence Length	677
Subcellular Localization	Mitochondrion .
Protein Description	May function as a regulatory ATPase and be related to secretion/protein trafficking process..
Protein Sequence	MMLSAVLRRTTPAPRLFLGLIKSPSLQSRGGAYGRGVVTGDRGEPQRLRAAAWVRPGASSTFVPGRGAATWGRRGERTEIPYLTAASSERGPSPEETLPGQDSWNGVPNKTGLGMWALAMALVVQCYSKNPSNKDAALMEAARANNVQEVRRLLSEGADVNARHKLGWTALMVASISHNESVVQVLLAAGADPNLGDEFSSVYKTANEQGVHSLEVLVTREDDFNNRLNHRASFKGCTALHYAVLADDYSIVKELLDRGANPLQRNEMGHTPLDYAREGEVMKLLKTSETKYMEKQRKREAEERRRFPLEQRLKEHIIGQESAIATVGAAIRRKENGWYDEEHPLVFLFLGSSGIGKTELAKQTAKYMHKDAKKGFIRLDMSEFQERHEVAKFIGSPPGYIGHEEGGQLTKKLKQCPNAVVLFDEVDKAHPDVLTIMLQLFDEGRLTDGKGKTIDCKDAIFIMTSNVASDEIAQHALQLRQEALEMSRNRIAENLGDVQMSDKITISKNFKENVIRPILKAHFRRDEFLGRINEIVYFLPFCHSELIQLVNKELNFWAKRAKQRHNITLLWDREVADVLVDGYNVHYGARSIKHEVERRVVNQLAAAYEQDLLPGGCTLRITVEDSDKHLLKSPELPSPQAEKRPPTLRLEIIDKDSKTRKLDIQAPLHPEKVCYTI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	LSAVLRRTTPAPRLF CHHHHCCCCCCCHHH	30.60	26239621
11	Phosphorylation	SAVLRRTTPAPRLFL HHHHCCCCCCCHHHH	18.68	26239621
366	Acetylation	ELAKQTAKYMHKDAK HHHHHHHHHHCHHHH	46.63	23201123
559	Acetylation	KELNFWAKRAKQRHN HHHHHHHHHHHHHCC	43.41	23864654
559	Malonylation	KELNFWAKRAKQRHN HHHHHHHHHHHHHCC	43.41	26320211
617	S-palmitoylation	QDLLPGGCTLRITVE HCCCCCCCEEEEEEC	3.92	28526873
638	Phosphorylation	LKSPELPSPQAEKRP CCCCCCCCCCHHHCC	42.12	25338131
657	Phosphorylation	LEIIDKDSKTRKLDI EEEECCCCCCCEEEE	41.49	30482847

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CLPB_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CLPB_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CLPB_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CLPB_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CLPB_MOUSE

Related Literatures of Post-Translational Modification