CLIP3_MOUSE - dbPTM
CLIP3_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CLIP3_MOUSE
UniProt AC B9EHT4
Protein Name CAP-Gly domain-containing linker protein 3
Gene Name Clip3
Organism Mus musculus (Mouse).
Sequence Length 547
Subcellular Localization Cell membrane
Lipid-anchor. Cytoplasm. Golgi apparatus, Golgi stack. Localized to Golgi stacks as well as on tubulovesicular elements juxtaposed to Golgi cisternae..
Protein Description Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes (By similarity)..
Protein Sequence MTKTDPAPMAPPPRGEEEEEEEEDEPVPEAPSPTQERRQKPVVHPSAPAPLPKDYAFTFFDPNDPACQEILFDPKTTIPELFAIVRQWVPQVQHKIDVIGNEILRRGCHVNDRDGLTDMTLLHYACKAGAHGVGDPAAAVRLSQQLLALGADVTLRSRWTNMNALHYAAYFDVPDLVRVLLKGARPRVVNSTCSDFNHGSALHIAASNLCLGAAKCLLEHGANPALRNRKGQVPAEVVPDPMDMSLDKAEAALVAKELRTLLEEAVPLSCTLPKVTLPNYDNVPGNLMLSALGLRLGDRVLLDGQKTGTLRFCGTTEFASGQWVGVELDEPEGKNDGSVGGVRYFICPPKQGLFASVSKVSKAVDAPPSSVTSTPRTPRMDFSRVTGKGRREHKGKKKSPSSPSLGSLQQREGAKAEVGDQVLVAGQKQGIVRFYGKTDFAPGYWYGIELDQPTGKHDGSVFGVRYFTCAPRHGVFAPASRIQRIGGSTDPPGDSVGAKKVHQVTMTQPKRTFTTVRTPKDIASENSISRLLFCCWFPWMLRAEMQS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MTKTDPAPMAP
----CCCCCCCCCCC		37.7425159016
32PhosphorylationEPVPEAPSPTQERRQ
CCCCCCCCCCCHHCC		47.8525521595
34PhosphorylationVPEAPSPTQERRQKP
CCCCCCCCCHHCCCC		47.6125521595
182UbiquitinationDLVRVLLKGARPRVV
HHHHHHHCCCCCEEE		46.4927667366
276PhosphorylationSCTLPKVTLPNYDNV
CCCCCCEECCCCCCC		42.4929514104
280PhosphorylationPKVTLPNYDNVPGNL
CCEECCCCCCCCCCH		13.6221454597
306UbiquitinationRVLLDGQKTGTLRFC
EEEECCCCCEEEEEC		55.2222790023
356PhosphorylationPKQGLFASVSKVSKA
CCCCCEEEHHHHHCC		21.4229514104
358PhosphorylationQGLFASVSKVSKAVD
CCCEEEHHHHHCCCC		25.5029514104
369PhosphorylationKAVDAPPSSVTSTPR
CCCCCCCCCCCCCCC		36.0619060867
370PhosphorylationAVDAPPSSVTSTPRT
CCCCCCCCCCCCCCC		34.8822817900
372PhosphorylationDAPPSSVTSTPRTPR
CCCCCCCCCCCCCCC		28.9119060867
373PhosphorylationAPPSSVTSTPRTPRM
CCCCCCCCCCCCCCC		33.9719060867
374PhosphorylationPPSSVTSTPRTPRMD
CCCCCCCCCCCCCCC		13.8722817900
377PhosphorylationSVTSTPRTPRMDFSR
CCCCCCCCCCCCHHH		19.2219060867
386PhosphorylationRMDFSRVTGKGRREH
CCCHHHCCCCCCCCC		31.8729899451
399PhosphorylationEHKGKKKSPSSPSLG
CCCCCCCCCCCCCHH		38.6025521595
401PhosphorylationKGKKKSPSSPSLGSL
CCCCCCCCCCCHHHH		63.0725521595
402PhosphorylationGKKKSPSSPSLGSLQ
CCCCCCCCCCHHHHH		23.1525521595
404PhosphorylationKKSPSSPSLGSLQQR
CCCCCCCCHHHHHHH		47.5125521595
407PhosphorylationPSSPSLGSLQQREGA
CCCCCHHHHHHHCCC		28.4429899451
428UbiquitinationQVLVAGQKQGIVRFY
EEEECCCCCEEEEEE		49.9622790023
456UbiquitinationELDQPTGKHDGSVFG
EECCCCCCCCCCEEE		40.7922790023
480PhosphorylationHGVFAPASRIQRIGG
CCCEECHHHCEECCC		28.93-
488PhosphorylationRIQRIGGSTDPPGDS
HCEECCCCCCCCCCC		25.1525338131
499UbiquitinationPGDSVGAKKVHQVTM
CCCCCCCEEEEEEEE		49.7727667366
510UbiquitinationQVTMTQPKRTFTTVR
EEEECCCCCEEEECC		55.0127667366
520UbiquitinationFTTVRTPKDIASENS
EEECCCHHHHCCCCH		62.2422790023
534S-palmitoylationSISRLLFCCWFPWML
HHHHHHHHHHHHHHH		1.70-
535S-palmitoylationISRLLFCCWFPWMLR
HHHHHHHHHHHHHHH		3.08-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CLIP3_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CLIP3_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CLIP3_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
AKT1_MOUSEAkt1physical
19139280
AKT2_MOUSEAkt2physical
19139280
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CLIP3_MOUSE

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Related Literatures of Post-Translational Modification

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