CLC_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLC_DROME
• UniProt AC: Q9VWA1
• Protein Name: Clathrin light chain
• Gene Name: Clc
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 219
• Subcellular Localization: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic face of coated pits and vesicles.
• Protein Description: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles..
• Protein Sequence: MDFGDDFAAKEDVDPAAEFLAREQSALGDLEAEITGGSASAPPAASTDEGLGELLGGTASEGDLLSAGGTGGLESSTGSFEVIGGESNEPVGISGPPPSREEPEKIRKWREEQKQRLEEKDIEEERKKEELRQQSKKELDDWLRQIGESISKTKLASRNAEKQAATLENGTIEPGTEWERIAKLCDFNPKVNKAGKDVSRMRSIYLHLKQNPIQVQKST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
203	Phosphorylation	KDVSRMRSIYLHLKQ CCHHHHHHHHHHHHH	13.27	19429919
205	Phosphorylation	VSRMRSIYLHLKQNP HHHHHHHHHHHHHCC	6.85	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLC_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLC_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLC_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.