CLCF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLCF1_HUMAN
• UniProt AC: Q9UBD9
• Protein Name: Cardiotrophin-like cytokine factor 1
• Gene Name: CLCF1
• Organism: Homo sapiens (Human).
• Sequence Length: 225
• Subcellular Localization: Secreted.
• Protein Description: Cytokine with B-cell stimulating capability. Binds to and activates the ILST/gp130 receptor..
• Protein Sequence: MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPGPGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETLPRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYPLPQPLPGTEPTWTPGPAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
29	N-linked_Glycosylation	LPAVPALNRTGDPGP CCCCCCCCCCCCCCC	41.39	UniProtKB CARBOHYD
56	Phosphorylation	YLEHQLRSLAGTYLN HHHHHHHHHHHHHHH	31.03	-
60	Phosphorylation	QLRSLAGTYLNYLGP HHHHHHHHHHHHHCC	21.16	-
96	Phosphorylation	VDLEVWRSLNDKLRL ECHHHHHHHHHHHHH	18.80	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLCF1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLCF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLCF1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CLCF1_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.