CLC2L_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLC2L_HUMAN
• UniProt AC: P0C7M8
• Protein Name: C-type lectin domain family 2 member L
• Gene Name: CLEC2L
• Organism: Homo sapiens (Human).
• Sequence Length: 214
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MEPAREPPSRARPPPPLAARPAPAPAAPRPRSPAEAEARGPEGLLRRSGSGYEGSTSWKAALEDTTTRLLLGAIAVLLFAILVVMSILASKGCIKCEAPCPEDWLLYGRKCYFFSEEPRDWNTGRQYCHTHEAVLAVIQSQKELEFMFKFTRREPWIGLRRVGDEFHWVNGDPFDPDTFTIAGPGECVFVEPTRLVSTECLMTRPWVCSKMAYT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
32	Phosphorylation	PAAPRPRSPAEAEAR CCCCCCCCHHHHHHH	31.01	26437602
48	Phosphorylation	PEGLLRRSGSGYEGS CCCCCCCCCCCCCCC	30.77	28060719
50	Phosphorylation	GLLRRSGSGYEGSTS CCCCCCCCCCCCCCC	39.17	29970186
52	Phosphorylation	LRRSGSGYEGSTSWK CCCCCCCCCCCCCHH	20.86	28270605
55	Phosphorylation	SGSGYEGSTSWKAAL CCCCCCCCCCHHHHH	13.82	28060719
56	Phosphorylation	GSGYEGSTSWKAALE CCCCCCCCCHHHHHH	49.84	28060719
57	Phosphorylation	SGYEGSTSWKAALED CCCCCCCCHHHHHHH	28.42	28060719

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLC2L_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLC2L_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLC2L_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CLC2L_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.