CLC1A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CLC1A_HUMAN
• UniProt AC: Q8NC01
• Protein Name: C-type lectin domain family 1 member A
• Gene Name: CLEC1A
• Organism: Homo sapiens (Human).
• Sequence Length: 280
• Subcellular Localization: Membrane ; Single-pass type II membrane protein .
• Protein Sequence: MQAKYSSTRDMLDDDGDTTMSLHSQGSATTRHPEPRRTEHRAPSSTWRPVALTLLTLCLVLLIGLAALGLLFFQYYQLSNTGQDTISQMEERLGNTSQELQSLQVQNIKLAGSLQHVAEKLCRELYNKAGAHRCSPCTEQWKWHGDNCYQFYKDSKSWEDCKYFCLSENSTMLKINKQEDLEFAASQSYSEFFYSYWTGLLRPDSGKAWLWMDGTPFTSELFHIIIDVTSPRSRDCVAILNGMIFSKDCKELKRCVCERRAGMVKPESLHVPPETLGEGD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
95	N-linked_Glycosylation	QMEERLGNTSQELQS HHHHHHCCCHHHHHH	40.94	UniProtKB CARBOHYD
169	N-linked_Glycosylation	KYFCLSENSTMLKIN CEEEECCCCEEEEEC	39.13	UniProtKB CARBOHYD
233	Phosphorylation	IDVTSPRSRDCVAIL HCCCCCCCCHHHHHH	35.54	25072903
246	Phosphorylation	ILNGMIFSKDCKELK HHCCEEECCCHHHHH	19.36	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CLC1A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CLC1A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CLC1A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCPG1_HUMAN	CCPG1	physical	26186194
CCPG1_HUMAN	CCPG1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.