CL040_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CL040_HUMAN
• UniProt AC: Q86WS4
• Protein Name: Uncharacterized protein C12orf40
• Gene Name: C12orf40
• Organism: Homo sapiens (Human).
• Sequence Length: 652
• Protein Sequence: MNWVGGSRSRVLIKQERRKQKEYFEKHRLKSKMKSLGVLSPVKNSAVSLDILNLYMVNQISCKKKIPETVRKPTHVNMNRDIKMPLRKHNLELTMSPHCVPSKLCLDDTETNVNCQRLSSKEDLGPVQSQGMDSYSMLHPQFSKIENCSFTPSSFSVELPSNRHISKLNFTSGIAPTPQKLAYEKKQNDQRSTVNCSDSLLSKLNKSQDVFSPSHKTTRFGTLFERLNSLGNRNLLTKSPAVIMDEDCRSTDEIRQSDYITEKHSIQHIWGKNGKEVSNFLEDVNQSTPNLLSENCDSFVSQNMINVLNIDEQRIKKTFNKCDYDSMGDTCVVTSSDKNHVTDRCIRNIFTVPELTFSNSTLNKTSYPEKCQPNKKYQREYNKNERNDLSTSFENDYYPSSSERKEKFENDYQEKTPQKSIQKYPANSMGNIPSEELHSKQSWDFGLDEILMEEGGIYSLKSKRISTKKISLDSAQSSRSTSYSPRPTDSCFSSSSDLPSEDEDQISQQIEDSNRMTIKTKEKMNNFYVERMAKLSGDRIVKNDDKIHKQNENFYQFSVKNNTDQFPQLQCNSAHILQNKTNDNCVLQAARCDAGIQTESESVMEEKLDVAIQCDLISKCTCRSDVSLCNLERCSGNIKADTTGGQEIHKNN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
35	Phosphorylation	RLKSKMKSLGVLSPV HHHHHHHHCCCCCCC	27.19	23186163
40	Phosphorylation	MKSLGVLSPVKNSAV HHHCCCCCCCCCCCH	25.82	23186163
48	Phosphorylation	PVKNSAVSLDILNLY CCCCCCHHHHHHHHH	21.75	-
55	Phosphorylation	SLDILNLYMVNQISC HHHHHHHHHHCHHCC	9.65	-
61	Phosphorylation	LYMVNQISCKKKIPE HHHHCHHCCCCCCCC	15.32	-
83	Acetylation	VNMNRDIKMPLRKHN CCCCCCCCCCHHHCC	38.46	19608861
102	Phosphorylation	MSPHCVPSKLCLDDT ECCCCCCCCEECCCC	20.19	-
161	Phosphorylation	SFSVELPSNRHISKL CEEEECCCCCCCCCC	60.15	-
199	Phosphorylation	STVNCSDSLLSKLNK CCCCCCHHHHHHHCC	18.21	24719451
214	Phosphorylation	SQDVFSPSHKTTRFG CCCCCCCCHHHCCHH	36.10	24260401
326	Phosphorylation	FNKCDYDSMGDTCVV HHCCCCCCCCCEEEE	20.59	28985074
330	Phosphorylation	DYDSMGDTCVVTSSD CCCCCCCEEEEECCC	11.06	28985074
335	Phosphorylation	GDTCVVTSSDKNHVT CCEEEEECCCCCCCC	25.57	28985074
412	Phosphorylation	KEKFENDYQEKTPQK HHHHCCCCHHCCCCH	30.10	18491316
459	Phosphorylation	MEEGGIYSLKSKRIS HHCCCEEEEECCCCC	27.66	24719451
471	Phosphorylation	RISTKKISLDSAQSS CCCCCEEECCHHHHH	34.70	26503514
474	Phosphorylation	TKKISLDSAQSSRST CCEEECCHHHHHCCC	33.24	29083192
477	Phosphorylation	ISLDSAQSSRSTSYS EECCHHHHHCCCCCC	27.69	29083192
478	Phosphorylation	SLDSAQSSRSTSYSP ECCHHHHHCCCCCCC	20.40	29083192
482	Phosphorylation	AQSSRSTSYSPRPTD HHHHCCCCCCCCCCC	25.51	24719451
484	Phosphorylation	SSRSTSYSPRPTDSC HHCCCCCCCCCCCCC	17.75	24719451
488	Phosphorylation	TSYSPRPTDSCFSSS CCCCCCCCCCCCCCC	41.65	30576142
490	Phosphorylation	YSPRPTDSCFSSSSD CCCCCCCCCCCCCCC	21.38	30576142
493	Phosphorylation	RPTDSCFSSSSDLPS CCCCCCCCCCCCCCC	33.37	30576142
555	Phosphorylation	HKQNENFYQFSVKNN HHCCCCEEEEEECCC	21.89	24043423

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CL040_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CL040_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CL040_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CL040_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.