CL004_HUMAN - dbPTM
CL004_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CL004_HUMAN
UniProt AC Q9NQ89
Protein Name Protein C12orf4
Gene Name C12orf4
Organism Homo sapiens (Human).
Sequence Length 552
Subcellular Localization Cytoplasm .
Protein Description Plays a role in mast cell degranulation..
Protein Sequence MKKNRERFCNREREFVYKFKVGSQCLELRVPLKFPVQENASHLHGRLMLLHSLPCFIEKDLKEALTQFIEEESLSDYDRDAEASLAAVKSGEVDLHQLASTWAKAYAETTLEHARPEEPSWDEDFADVYHDLIHSPASETLLNLEHNYFVSISELIGERDVELKKLRERQGIEMEKVMQELGKSLTDQDVNSLAAQHFESQQDLENKWSNELKQSTAIQKQEYQEWVIKLHQDLKNPNNSSLSEEIKVQPSQFRESVEAIGRIYEEQRKLEESFTIHLGAQLKTMHNLRLLRADMLDFCKHKRNHRSGVKLHRLQTALSLYSTSLCGLVLLVDNRINSYSGIKRDFATVCQECTDFHFPRIEEQLEVVQQVVLYARTQRRSKLKESLDSGNQNGGNDDKTKNAERNYLNVLPGEFYITRHSNLSEIHVAFHLCVDDHVKSGNITARDPAIMGLRNILKVCCTHDITTISIPLLLVHDMSEEMTIPWCLRRAELVFKCVKGFMMEMASWDGGISRTVQFLVPQSISEEMFYQLSNMLPQIFRVSSTLTLTSKH
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
10UbiquitinationKNRERFCNREREFVY
CCHHHHCCCCCEEEE		46.2522817900
33UbiquitinationLELRVPLKFPVQENA
EEEECCCCCCCCCCC		41.36-
34UbiquitinationELRVPLKFPVQENAS
EEECCCCCCCCCCCC		10.6422817900
40UbiquitinationKFPVQENASHLHGRL
CCCCCCCCCHHCHHH		9.5129967540
47UbiquitinationASHLHGRLMLLHSLP
CCHHCHHHHHHHCCC		3.1621890473
52PhosphorylationGRLMLLHSLPCFIEK
HHHHHHHCCCHHHHH		33.6925627689
62UbiquitinationCFIEKDLKEALTQFI
HHHHHHHHHHHHHHH		51.5833845483
74UbiquitinationQFIEEESLSDYDRDA
HHHHHHCCCCCCCCH		5.2321963094
89UbiquitinationEASLAAVKSGEVDLH
HHHHHHHHHCCCCHH		48.2829967540
90PhosphorylationASLAAVKSGEVDLHQ
HHHHHHHHCCCCHHH		33.32-
176AcetylationRQGIEMEKVMQELGK
HHCCCHHHHHHHHHH		41.5220167786
183UbiquitinationKVMQELGKSLTDQDV
HHHHHHHHCCCHHHH		55.7221906983
207UbiquitinationSQQDLENKWSNELKQ
HHHHHHHHHHHHHHH		42.4921906983
212UbiquitinationENKWSNELKQSTAIQ
HHHHHHHHHHCHHHH		7.7629901268
213UbiquitinationNKWSNELKQSTAIQK
HHHHHHHHHCHHHHH		35.7029967540
220UbiquitinationKQSTAIQKQEYQEWV
HHCHHHHHHHHHHHH		38.7021906983
235UbiquitinationIKLHQDLKNPNNSSL
HHHHHHHCCCCCCCC		77.8633845483
240PhosphorylationDLKNPNNSSLSEEIK
HHCCCCCCCCCHHHC		39.0226657352
241PhosphorylationLKNPNNSSLSEEIKV
HCCCCCCCCCHHHCC		37.7326657352
243PhosphorylationNPNNSSLSEEIKVQP
CCCCCCCCHHHCCCH		34.8229514088
247UbiquitinationSSLSEEIKVQPSQFR
CCCCHHHCCCHHHHH		37.7921906983
256PhosphorylationQPSQFRESVEAIGRI
CHHHHHHHHHHHHHH		22.4730622161
264PhosphorylationVEAIGRIYEEQRKLE
HHHHHHHHHHHHHHH		16.44-
267UbiquitinationIGRIYEEQRKLEESF
HHHHHHHHHHHHHCE		35.5533845483
280UbiquitinationSFTIHLGAQLKTMHN
CEEEEEHHHHHHHHH		20.2129901268
323UbiquitinationTALSLYSTSLCGLVL
HHHHHHHHCCCCHHH		16.5029901268
335UbiquitinationLVLLVDNRINSYSGI
HHHHHCCCHHHCCCC		25.6333845483
343UbiquitinationINSYSGIKRDFATVC
HHHCCCCCCHHHHHH		49.82-
378UbiquitinationVVLYARTQRRSKLKE
HHHHHHHHCHHHHHH		32.9833845483
384UbiquitinationTQRRSKLKESLDSGN
HHCHHHHHHHHHCCC		49.33-
389PhosphorylationKLKESLDSGNQNGGN
HHHHHHHCCCCCCCC		44.96-
453UbiquitinationRDPAIMGLRNILKVC
CCHHHHHHHHHHHHH		1.7829901268
496UbiquitinationRRAELVFKCVKGFMM
HHHHHHHHHHHHHHH		30.5529901268
508UbiquitinationFMMEMASWDGGISRT
HHHHHHHCCCCHHCE		9.9533845483
551UbiquitinationSTLTLTSKH------
CEEEEECCC------		48.3633845483
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CL004_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CL004_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CL004_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CL004_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CL004_HUMAN

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Related Literatures of Post-Translational Modification

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