CKAP4_MOUSE - dbPTM
CKAP4_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CKAP4_MOUSE
UniProt AC Q8BMK4
Protein Name Cytoskeleton-associated protein 4
Gene Name Ckap4
Organism Mus musculus (Mouse).
Sequence Length 575
Subcellular Localization Endoplasmic reticulum membrane
Single-pass type II membrane protein. Cell membrane
Single-pass type II membrane protein. Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Translocates to the perinuclear region upon APF-stimulation..
Protein Description High-affinity epithelial cell surface receptor for APF.; Mediates the anchoring of the endoplasmic reticulum to microtubules..
Protein Sequence MPSAKQRGSKGGHGAASPSDKGAHPSGGADDVAKKPPAAPQQPQPPAPHPPQHPQNQAHRGGHRGRSSAATANASSASCSRRLGRVLNFLFYLSLVAAAAFSGWYVHHVLEEVQQVRRGHQDFSRQRDELGQGLQGVEQKVQSLQATFGTFESLLRNSQHKQDLTEKAVKEGESELNRISEVLQKLQNEILKDLSDGIHVVKDARERDFTSLENTVEERLTELTKSINDNIAIFTDVQKRSQKEINEVKMKVASLEESKGDRSQDVKTLKDAVKEVQASMMSRERDIEALKSSLQTMESDVYTEVRELVSLKQEQQAFKQAADSERLALQALTEKLLRSEESSSRLPEDIRRLEEELQQLKVGAHGSEEGAVFKDSKALEELQRQIEGLGARLQYVEDGVYSMQVASARHTESLESLLSKSQEYEQRLAMLQEHVGNLGSSSDLASTVRSLGETQLALSSDLKELKQSLGELPGTVESLQEQVLSLLSQDQAQAEGLPPQDFLDRLSSLDNLKSSVSQVESDLKMLRTAVDSLVAYSVKIETNENNLESAKGLLDDLRNDLDRLFLKVEKIHEKI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
3Phosphorylation-----MPSAKQRGSK
-----CCCHHHCCCC		46.96-
9PhosphorylationPSAKQRGSKGGHGAA
CCHHHCCCCCCCCCC		30.2529514104
17PhosphorylationKGGHGAASPSDKGAH
CCCCCCCCCCCCCCC		25.1425159016
19PhosphorylationGHGAASPSDKGAHPS
CCCCCCCCCCCCCCC		49.8425159016
21AcetylationGAASPSDKGAHPSGG
CCCCCCCCCCCCCCC		63.4323806337
26PhosphorylationSDKGAHPSGGADDVA
CCCCCCCCCCCCCCC		39.7426824392
60MethylationHPQNQAHRGGHRGRS
CCCCCCCCCCCCCCC		56.66-
64MethylationQAHRGGHRGRSSAAT
CCCCCCCCCCCCCHH		45.56-
67PhosphorylationRGGHRGRSSAATANA
CCCCCCCCCCHHCCC		27.4425521595
68PhosphorylationGGHRGRSSAATANAS
CCCCCCCCCHHCCCC		22.1425159016
71PhosphorylationRGRSSAATANASSAS
CCCCCCHHCCCCHHH		21.8425777480
75PhosphorylationSAATANASSASCSRR
CCHHCCCCHHHHHHH		26.6725777480
76PhosphorylationAATANASSASCSRRL
CHHCCCCHHHHHHHH		23.0725777480
78PhosphorylationTANASSASCSRRLGR
HCCCCHHHHHHHHHH		17.9925777480
79S-palmitoylationANASSASCSRRLGRV
CCCCHHHHHHHHHHH		3.52-
80PhosphorylationNASSASCSRRLGRVL
CCCHHHHHHHHHHHH		20.2425777480
185AcetylationRISEVLQKLQNEILK
HHHHHHHHHHHHHHH		48.1322826441
192AcetylationKLQNEILKDLSDGIH
HHHHHHHHHHHCCCE		63.3822826441
202AcetylationSDGIHVVKDARERDF
HCCCEECCCHHHCCC		44.5822902405
210PhosphorylationDARERDFTSLENTVE
CHHHCCCCCHHHHHH		36.3724899341
211PhosphorylationARERDFTSLENTVEE
HHHCCCCCHHHHHHH		33.4124899341
215PhosphorylationDFTSLENTVEERLTE
CCCCHHHHHHHHHHH		21.6623984901
263PhosphorylationEESKGDRSQDVKTLK
HHHCCCCHHHHHHHH		35.1626824392
292PhosphorylationRDIEALKSSLQTMES
HHHHHHHHHHHHHHH		36.81-
312SuccinylationVRELVSLKQEQQAFK
HHHHHHHHHHHHHHH		44.2623806337
312AcetylationVRELVSLKQEQQAFK
HHHHHHHHHHHHHHH		44.2623806337
335AcetylationALQALTEKLLRSEES
HHHHHHHHHHCCHHH		47.8122826441
367PhosphorylationLKVGAHGSEEGAVFK
HCCCCCCCCCCCCCC		23.7025521595
507PhosphorylationQDFLDRLSSLDNLKS
HHHHHHHHHHHHHHH		29.7420531401
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CKAP4_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference
79CPalmitoylation

-
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CKAP4_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CKAP4_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CKAP4_MOUSE

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Related Literatures of Post-Translational Modification

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