CK068_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CK068_HUMAN
• UniProt AC: Q9H3H3
• Protein Name: UPF0696 protein C11orf68
• Gene Name: C11orf68
• Organism: Homo sapiens (Human).
• Sequence Length: 251
• Protein Sequence: MEPGEELEEEGSPGGREDGFTAEHLAAEAMAADMDPWLVFDARTTPATELDAWLAKYPPSQVTRYGDPGSPNSEPVGWIAVYGQGYSPNSGDVQGLQAAWEALQTSGRPITPGTLRQLAITHHVLSGKWLMHLAPGFKLDHAWAGIARAVVEGQLQVAKVSPRAKEGGRQVICVYTDDFTDRLGVLEADSAIRAAGIKCLLTYKPDVYTYLGIYRANRWHLCPTLYESRFQLGGSARGSRVLDRANNVELT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	EELEEEGSPGGREDG HHHCCCCCCCCCCCC	24.53	29255136
14	Methylation	LEEEGSPGGREDGFT HCCCCCCCCCCCCCC	49.87	-
14 (in isoform 2)	Methylation	-	49.87	-
22	Methylation	GREDGFTAEHLAAEA CCCCCCCHHHHHHHH	10.43	-
22 (in isoform 2)	Methylation	-	10.43	-
27	Methylation	FTAEHLAAEAMAADM CCHHHHHHHHHHCCC	16.08	-
27 (in isoform 2)	Methylation	-	16.08	-
29	Methylation	AEHLAAEAMAADMDP HHHHHHHHHHCCCCC	6.54	24129315
29 (in isoform 2)	Methylation	-	6.54	-
41 (in isoform 3)	Phosphorylation	-	27.88	22210691
53 (in isoform 2)	Phosphorylation	-	9.12	25849741
54 (in isoform 3)	Phosphorylation	-	2.94	22210691
54	Phosphorylation	ATELDAWLAKYPPSQ CHHHHHHHHHCCHHH	2.94	27251275
111	Phosphorylation	QTSGRPITPGTLRQL HHCCCCCCCCHHHHH	20.53	20068231
114	Phosphorylation	GRPITPGTLRQLAIT CCCCCCCHHHHHHHH	21.70	20068231
159	Ubiquitination	EGQLQVAKVSPRAKE HCCEEEEEECCCHHC	44.37	-
203	Phosphorylation	GIKCLLTYKPDVYTY CCEEEEEECCCHHHH	22.09	-
208	Phosphorylation	LTYKPDVYTYLGIYR EEECCCHHHHEEEEE	9.31	-
214	Phosphorylation	VYTYLGIYRANRWHL HHHHEEEEECCCEEE	11.24	22210691
235	Phosphorylation	SRFQLGGSARGSRVL CCCCCCCCCHHCCCH	17.00	22617229
237	Methylation	FQLGGSARGSRVLDR CCCCCCCHHCCCHHC	45.37	-
251	Phosphorylation	RANNVELT------- CCCCEECC-------	24.06	22199227
277	Phosphorylation	--------------------------------- ---------------------------------		24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CK068_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CK068_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CK068_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SH3G3_HUMAN	SH3GL3	physical	16169070

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.