CISD2_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CISD2_DROME
• UniProt AC: Q9VAM6
• Protein Name: CDGSH iron-sulfur domain-containing protein 2 homolog
• Gene Name: Cisd2 {ECO:0000312|FlyBase:FBgn0062442}
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 133
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass membrane protein .
• Protein Sequence: MEPISHLVKSSLPNYLSSLPVPDSIGGWFKLSFKDWLALIPPTVVVAGLGYTAYLAYCPAARASCAAKNSGRCNNHIRKNEPKVVDMIDVEDIAEKAAFCRCWKTKNWPYCDGSHGEHNKQTGDNVGPIVIKK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
83	Acetylation	HIRKNEPKVVDMIDV CCCCCCCCEECEECH	49.03	21791702
132	Acetylation	NVGPIVIKK------ CCCCEEEEC------	41.35	21791702
133	Ubiquitination	VGPIVIKK------- CCCEEEEC-------	55.22	31113955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CISD2_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CISD2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CISD2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.