| UniProt ID | CIP2A_MOUSE | |
|---|---|---|
| UniProt AC | Q8BWY9 | |
| Protein Name | Protein CIP2A | |
| Gene Name | Cip2a | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 907 | |
| Subcellular Localization |
Membrane Single-pass membrane protein . Cytoplasm . Slightly concentrates in the perinuclear region. |
|
| Protein Description | Promotes anchorage-independent cell growth and tumor formation.. | |
| Protein Sequence | MDSTACLKSLLLSISQYKAVKSEANATQLLRHLEVVSGQKLTRLFTSHQILPSECLSCLVELLEDPNISASLILSIISLLSQLAIDNETRDCLQNIYNLNSVLSGVVCRSSACHNDSVFLQCIQLLQRLTYNAKFFHSGAHIDDLITFLIGHVQSSEDELTMPCLGLLANLCRHNLSVQTQIKTLSNVKSFYRTLISFLAHSSLTVVVFALSILSSLTLNEEVGEKLFHARNIHQTFQLIFNILINGDGTLTRKYSVDLLMDLLKNPKIADYLTRYEHFSSCLSQVLGLLNAKDPDSSSKVLELLLAFCAVTQLRHVLSQMMFEQSPSGNILGSRPKSLEPTAALLRWLSQPLDGAENCSVLALELFKEIFEDVIDTGNCSSTDHFVTLLLPTILDQLQFKEQNLDETLVRNKCERMVKAIEVLLTLCGDDSLKMHVVKILTTLKCTTLIEQQFTYGKIDLGFGTKVADSELCKLAADVILKTLTLMNKLKQLVPGMEVSFYKILQDPRLITPLAFALTSDNREQVQSGLGILLEASPLPDFPAFVLGESIAANNVYRQQETEHLPRKMTFQPLNHGFSTSAKCLTPPPSKDNAPALNIEDLIEKLQAGVMVKDQISDIRISDIMDVYEMKLSTLASKESRLQDLLEAKALALAQADRLIAQYRCQRTQAETEARTLAGMLREVERKNEELSVLLKSQQLESERAQNDIEHLFQHSKKLESVAAEHEILTKSYMELVQRNEATEKKNTDLQTTCESLNKHIETMKKLNEALKQQNEKTIAQLIEKEEQRKEVQSQLADRECKLSNLHKIAKSQEEKLNVLQKEKEDKQETIDILRKELSRTEQIRKELSIKASSLEMHKAQLEGRLEEKESLLKLQQEELNKHSHMIAMIHSLSGGKISPETVNLSI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MDSTACLK -------CCHHHHHH | 9.18 | - | |
| 40 | Acetylation | LEVVSGQKLTRLFTS HHHHCCCCHHHHHHC | 56.18 | 23236377 | |
| 338 | Phosphorylation | ILGSRPKSLEPTAAL CCCCCCCCCHHHHHH | 40.42 | 26824392 | |
| 512 | Phosphorylation | LQDPRLITPLAFALT HCCCCCHHHHHEHHC | 19.49 | 25777480 | |
| 519 | Phosphorylation | TPLAFALTSDNREQV HHHHEHHCCCCHHHH | 30.52 | 25777480 | |
| 520 | Phosphorylation | PLAFALTSDNREQVQ HHHEHHCCCCHHHHH | 33.47 | 25777480 | |
| 586 | Phosphorylation | STSAKCLTPPPSKDN CCCCCCCCCCCCCCC | 43.13 | 22942356 | |
| 590 | Phosphorylation | KCLTPPPSKDNAPAL CCCCCCCCCCCCCCC | 59.42 | 26745281 | |
| 884 | Phosphorylation | QEELNKHSHMIAMIH HHHHHHHHHHHHHHH | 19.16 | 26643407 | |
| 892 | Phosphorylation | HMIAMIHSLSGGKIS HHHHHHHHHHCCCCC | 17.19 | 23649490 | |
| 894 | Phosphorylation | IAMIHSLSGGKISPE HHHHHHHHCCCCCHH | 48.81 | 23649490 | |
| 899 | Phosphorylation | SLSGGKISPETVNLS HHHCCCCCHHHCCCC | 21.85 | 25266776 | |
| 902 | Phosphorylation | GGKISPETVNLSI-- CCCCCHHHCCCCC-- | 20.34 | 26824392 | |
| 906 | Phosphorylation | SPETVNLSI------ CHHHCCCCC------ | 22.50 | 26643407 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CIP2A_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CIP2A_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CIP2A_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CIP2A_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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