CINV2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CINV2_ARATH
• UniProt AC: Q67XD9
• Protein Name: Alkaline/neutral invertase CINV2 {ECO:0000305}
• Gene Name: CINV2 {ECO:0000303|PubMed:19470642}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 558
• Subcellular Localization: Cytoplasm, cytosol .
• Protein Description: Cytosolic invertase that may cleave sucrose into glucose and fructose, and that is involved in the regulation of root growth. May regulate sugar-mediated root development by controlling sucrose catabolism in root cells..
• Protein Sequence: MEEGHKEPLVLRVEGSHCSLSEMDDFDLTRALEKPRQLKIERKRSFDERSMSELSTGYVRQDSILEMAHSPGSRSMVDTPLSVRNSFEPHPMVAEAWEALRRSMVFFRGQPVGTIAAYDHASEEVLNYDQVFVRDFVPSALAFLMNGEPDIVKNFLLKTLQLQGWEKRVDRFKLGEGVMPASFKVLHDPVRKTDTIIADFGESAIGRVAPVDSGFWWIILLRAYTKSTGDLTLSETPECQRGMRLILSLCLSEGFDTFPTLLCADGCSMVDRRMGVYGYPIEIQALFFMALRCALSMLKPDEEGRDFIERIVKRLHALSFHMRSYFWLDFQQLNDIYRYKTEEYSHTAVNKFNVMPDSIPDWVFDFMPLRGGYFVGNVSPARMDFRWFSLGNCVSILSSLATPDQSMAIMDLLEHRWEELVGEMPLKICYPCIESHEWRIVTGCDPKNTRWSYHNGGSWPVLLWTLTAACIKTGRPQIARRAIDLIESRLHRDCWPEYYDGKQGRYVGKQARKYQTWSIAGYLVAKMMLEDPSHIGMISLEEDKQMKPVIKRSASWTC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	LVLRVEGSHCSLSEM EEEEEECCCCCHHHC		19880383
19	Phosphorylation	RVEGSHCSLSEMDDF EEECCCCCHHHCCCC		23572148
45	Phosphorylation	LKIERKRSFDERSMS HCCEECCCCCHHHHH		23776212
50	Phosphorylation	KRSFDERSMSELSTG CCCCCHHHHHHHHCC		23111157
52	Phosphorylation	SFDERSMSELSTGYV CCCHHHHHHHHCCCC		19880383
55	Phosphorylation	ERSMSELSTGYVRQD HHHHHHHHCCCCCCH		30407730
56	Phosphorylation	RSMSELSTGYVRQDS HHHHHHHCCCCCCHH		25561503
58	Phosphorylation	MSELSTGYVRQDSIL HHHHHCCCCCCHHHH		25561503
63	Phosphorylation	TGYVRQDSILEMAHS CCCCCCHHHHHHCCC		23776212
70	Phosphorylation	SILEMAHSPGSRSMV HHHHHCCCCCCHHHC		30291188
73	Phosphorylation	EMAHSPGSRSMVDTP HHCCCCCCHHHCCCC		23776212
75	Phosphorylation	AHSPGSRSMVDTPLS CCCCCCHHHCCCCCC		23776212
79	Phosphorylation	GSRSMVDTPLSVRNS CCHHHCCCCCCCCCC		23776212
82	Phosphorylation	SMVDTPLSVRNSFEP HHCCCCCCCCCCCCC		23776212
555	Phosphorylation	PVIKRSASWTC---- CCCHHHCCCCC----		19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CINV2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CINV2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CINV2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of CINV2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.