dbPTM

CHR1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CHR1_SCHPO
UniProt AC	O59732
Protein Name	Chitin synthase regulatory factor 1
Gene Name	chr1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	456
Subcellular Localization
Protein Description	Involved in chitin biosynthesis..
Protein Sequence	MPASTSIPETPSKLPDALLVNSDPASKVDNVSVKIEQESPLALEGSPLPTVSDVLPETNNAHEEVSSSSWSLSSSDSIMSYDSLSDDVSVLSFLDCPLTTFETAPSIASFSNSAADVSSHSRSSSSWSAKLSRFTKHASKPSLSSNSSDSSFSKSGSESNALSSRGSFELEPHGIHRHVSRAKRLLSKFYSKFHHKKEDSSFDPLAPLVFAPNTSRVLRVTNEANASAISLEKATSLSSQEQPGSEIKKELSLYDHEFDQILDLAIKAKKDGNLENAIEFLEYIMPEVASQQNFVPYELAELYKQRGTSQDLKSILPLYMLAASLGHDRSSFLVGEAFFYGTYGARENKLRALQYYHLANDKGNADAMLALCKLYLRGLPGHIFPSSRRAFEYAHRAAMLGHAPACYVLGKFYETGVGCVKDLAKSEAGFRAGLINDSPITDADALQIASTLVLLQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MPASTSIPETP ----CCCCCCCCCCC	19.47	29996109
6	Phosphorylation	--MPASTSIPETPSK --CCCCCCCCCCCCC	33.38	29996109
150	Phosphorylation	LSSNSSDSSFSKSGS CCCCCCCCCCCCCCC	34.92	24763107
153	Phosphorylation	NSSDSSFSKSGSESN CCCCCCCCCCCCCCC	28.05	24763107
167	Phosphorylation	NALSSRGSFELEPHG CCCCCCCCEECCCCC	17.90	29996109
214	Phosphorylation	PLVFAPNTSRVLRVT CEEECCCCCCEEEEC	19.49	25720772
215	Phosphorylation	LVFAPNTSRVLRVTN EEECCCCCCEEEECC	27.34	25720772
227	Phosphorylation	VTNEANASAISLEKA ECCCCCCCEEEHHHH	26.41	28889911
230	Phosphorylation	EANASAISLEKATSL CCCCCEEEHHHHHHC	30.14	28889911
235	Phosphorylation	AISLEKATSLSSQEQ EEEHHHHHHCCCCCC	41.07	25720772
236	Phosphorylation	ISLEKATSLSSQEQP EEHHHHHHCCCCCCC	30.98	24763107
238	Phosphorylation	LEKATSLSSQEQPGS HHHHHHCCCCCCCCC	29.73	25720772
239	Phosphorylation	EKATSLSSQEQPGSE HHHHHCCCCCCCCCH	42.92	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CHR1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CHR1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CHR1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CHR1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CHR1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-227 AND SER-230, ANDMASS SPECTROMETRY.	18257517 [Abstract]