CHR12_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CHR12_ARATH
• UniProt AC: F4J9M5
• Protein Name: Probable ATP-dependent DNA helicase CHR12
• Gene Name: CHR12 {ECO:0000303|PubMed:16547115}
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1102
• Subcellular Localization: Nucleus.
• Protein Description: Probable chromatin-remodeling factor that is functionally redundant with CHR23 in root and shoot stem cell initiation, and root apical meristem (RAM) and shoot apical meristem (SAM) maintenance. Plays an important role in mediating the temporary plant growth arrest induced upon perception of stress. [PubMed: 17605754]
• Protein Sequence: MVAQQLQERCGGTSQEDPVETTKSLICALNYISRDLPLPPHLFTAVSSIYHGASSSSLSDSDVSPPLPTSPPANKAPYGADLMGEFEDALLKQRPDCESGSRLIQLLDNRNKSHIQRRLSELEELPSTRGEDLQAKCLLELYGLKLRELQGKVRTAVSSEFWLRLNCADVSSQVFDWGMMRLPRPFYGVGDPFAMEADDQFRKKRDAERLSRLEEEEKNLIETAKRKFFAEVLNAVREFQLQIQATQKRRRQRNDGVQAWHGRQRQRATRAEKLRLMALKSDDQEAYMKLVKESKNERLTTLLEETNKLLANLGAAVQRQKDAKLPEGIDLLKDSESDLSELDAPRSEPLQDLLPDQDIDITESDNNDDSNDLLEGQRQYNSAIHSIQEKVTEQPSLLEGGELRSYQLEGLQWMVSLFNNNLNGILADEMGLGKTIQTISLIAYLLENKGVPGPYLIVAPKAVLPNWVNEFATWVPSIAAFLYDGRLEERKAIREKIAGEGKFNVLITHYDLIMRDKAFLKKIEWYYMIVDEGHRLKNHESALAKTLLTGYRIKRRLLLTGTPIQNSLQELWSLLNFLLPHIFNSVQNFEEWFNAPFADRGNVSLTDEEELLIIHRLHHVIRPFILRRKKDEVEKFLPGKTQVILKCDMSAWQKVYYKQVTDMGRVGLQTGSGKSKSLQNLTMQLRKCCNHPYLFVGGDYNMWKKPEIVRASGKFELLDRLLPKLRKAGHRILLFSQMTRLIDVLEIYLTLNDYKYLRLDGTTKTDQRGLLLKQFNEPDSPYFMFLLSTRAGGLGLNLQTADTVIIFDSDWNPQMDQQAEDRAHRIGQKKEVRVFVLVSVGSVEEVILERAKQKMGIDAKVIQAGLFNTTSTAQDRREMLEEIMRKGTSSLGTDVPSEREINRLAARSEDEFWMFERMDEERRRKENYRARLMQEQEVPEWAYTTQTQEEKLNNGKFHFGSVTGKRKRKEIVYSDTLSELQWLKAVESGEDLSKLSMRYNRREENASNTKTSTSKKVIESIQTVSDGTSEEDEEEQEEERAKEMSGKQRVDKSEEEEEEGEEENDGKAIFKWNTHKKKRSRYSFTCSSSDSRAQSSNGSRRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
127	Phosphorylation	SELEELPSTRGEDLQ HHHHHCCCCCCHHHH		25368622
128	Phosphorylation	ELEELPSTRGEDLQA HHHHCCCCCCHHHHH		25368622
335	Phosphorylation	GIDLLKDSESDLSEL CCCHHCCCCCCHHHC		27531888
337	Phosphorylation	DLLKDSESDLSELDA CHHCCCCCCHHHCCC		27531888
340	Phosphorylation	KDSESDLSELDAPRS CCCCCCHHHCCCCCC		27531888
362	Phosphorylation	PDQDIDITESDNNDD CCCCCCCCCCCCCCC		30407730
364	Phosphorylation	QDIDITESDNNDDSN CCCCCCCCCCCCCCC		30407730
370	Phosphorylation	ESDNNDDSNDLLEGQ CCCCCCCCCCHHHHH		30407730
988	Phosphorylation	QWLKAVESGEDLSKL HHHHHHHCCCCHHHH		19880383
993	Phosphorylation	VESGEDLSKLSMRYN HHCCCCHHHHHHHHH		25561503
1025	Phosphorylation	IESIQTVSDGTSEED HHHHHHCCCCCCHHH		27531888
1028	Phosphorylation	IQTVSDGTSEEDEEE HHHCCCCCCHHHHHH		27531888
1029	Phosphorylation	QTVSDGTSEEDEEEQ HHCCCCCCHHHHHHH		27531888
1053	Phosphorylation	GKQRVDKSEEEEEEG CCCCCCCCHHHHHCC		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CHR12_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CHR12_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CHR12_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of CHR12_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.