CFA44_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CFA44_HUMAN
• UniProt AC: Q96MT7
• Protein Name: Cilia- and flagella-associated protein 44 {ECO:0000312|HGNC:HGNC:25631}
• Gene Name: CFAP44 {ECO:0000312|HGNC:HGNC:25631}
• Organism: Homo sapiens (Human).
• Sequence Length: 982
• Subcellular Localization: Cell projection, cilium, flagellum .
• Protein Sequence: MKEPDDQDTDGEKSVTSKSDGKKSLRSSKSESRSPVQEDNTFLEDDTDETFTKGEGSYLEEDSDEERLEGSLSSFQYGDLQSTTVPQQTPAPAVEEAEEEVKKKISESFFYDYMELASMPFVTLDSNIPLDLLTLVHSFGYDCRKRANLQLLDDSIAIYIAGNQLIFLNLKTKEQIYLRSSSGEGIGVIGVHPHKTYFTVAEKGSFPDIIIYEYPSLRPYRVLRDGTEKGYAYVDFNYSGNLLASVGSNPDYTLTIWNWKEEQPILRTKAFSQEVFKVTFNPDKEEQLTTSGSGHIKFWEMAFTFTGLKLQGSLGRFGKTITTDIEGYMELPDGKVLSGSEWGNMLLWEGGLIKVELCRGTSKSCHNGPINQIMLYEGEVITVGSDGYVRIWDFETIDTADVIDETGLLEIEPINELQVDKNVNLFSMIKMNETGNNFWLAQDANGAIWKLDLSFSNITQDPECLFSFHSGAIEAVAVSPLTYLMATTALDCSVRIYDFASKTPLAQMKFKQGGTALVWVPRMVNFTGAQIIVGFEDGVVRILELYDPKGLTIFAGRKKILDADIQLKQVFKPHTACVTALAYERDGEILATGSKDQTVFFFEVERDYKPIGYINTPGPVCQLMWSPMSHPESTLLIICENGYILEAPLPTIKQEEDDHDVVSYEIKDMCIKCFHFSSVKSKILRLIEIEKRERQRELKEKIREERRNKLAAEMGEDGEKEFQEEEEEKEEEEEEEEPLPEIFIPSTPSPILCGFYSEPGKFWVSLGGYDSGFLYHCEFPPCDESSDFKEQKDEPIDVRYLADTEDNPIQTITFNINKVMMFCGMKNGAIRVYVLNQNDPSLTSLVDYWHFNMHDNNYGCIKSIANSFDDRFLVTAGADGNIFVFNIFSEFMLRKDMKAKVPSPRFGIETEPIPEDIEDPKAYSIENARRKREHDKLMKEVGEIKARKREQIKALRSEFCNLLEMNEKLPKHMQFKRTVSLI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
197	Phosphorylation	GVHPHKTYFTVAEKG EECCCCEEEEEECCC		-
268	Phosphorylation	EEQPILRTKAFSQEV CCCCEEEHHCCCCEE		17081983
293	Phosphorylation	EQLTTSGSGHIKFWE HCCCCCCCCCEEEEE		24505115
313	Phosphorylation	TGLKLQGSLGRFGKT ECEEEECCCCCCCCE		26852163
361	Phosphorylation	KVELCRGTSKSCHNG EEEEECCCCCCCCCC		28787133
362	Phosphorylation	VELCRGTSKSCHNGP EEEECCCCCCCCCCC		28787133
497	Phosphorylation	LDCSVRIYDFASKTP HHCEEEEEECCCCCC		20049867
501	Phosphorylation	VRIYDFASKTPLAQM EEEEECCCCCCCCEE		20049867
503	Phosphorylation	IYDFASKTPLAQMKF EEECCCCCCCCEEEC		20049867
811	Phosphorylation	TEDNPIQTITFNINK CCCCCCEEEEEECCC		29116813
813	Phosphorylation	DNPIQTITFNINKVM CCCCEEEEEECCCCE		29116813
833	Phosphorylation	KNGAIRVYVLNQNDP CCCEEEEEEECCCCC		18083107
858	Phosphorylation	FNMHDNNYGCIKSIA ECCCCCCCHHHHHHH		18083107
898	Acetylation	FMLRKDMKAKVPSPR HHCCHHHHCCCCCCC		19811367
903	Phosphorylation	DMKAKVPSPRFGIET HHHCCCCCCCCCCCC		30622161
978	Phosphorylation	KHMQFKRTVSLI--- HHHCCCCCEECC---		23403867
980	Phosphorylation	MQFKRTVSLI----- HCCCCCEECC-----		23403867
1083	Phosphorylation	------------------------------------------------------------------------------------------------------------ ------------------------------------------------------------------------------------------------------------		19690332
1090 (in isoform 2)	Phosphorylation	-		22210691
1092 (in isoform 2)	Phosphorylation	-		22210691
1109 (in isoform 2)	Phosphorylation	-		30622161
1111 (in isoform 2)	Phosphorylation	-		30622161
1330 (in isoform 2)	Phosphorylation	-		30622161
1331 (in isoform 2)	Phosphorylation	-		30622161
1333 (in isoform 2)	Phosphorylation	-		30622161
1364 (in isoform 2)	Phosphorylation	-		30622161
1368 (in isoform 2)	Phosphorylation	-		30622161
1438 (in isoform 2)	Phosphorylation	-		29523821
1446 (in isoform 2)	Phosphorylation	-		29523821
1519 (in isoform 2)	Phosphorylation	-		25137130
1520 (in isoform 2)	Phosphorylation	-		25137130
1768 (in isoform 2)	Phosphorylation	-		26546556
1835 (in isoform 2)	Phosphorylation	-		30622161
1843 (in isoform 2)	Phosphorylation	-		30622161

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CFA44_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CFA44_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CFA44_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CFA44_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.