CFA43_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CFA43_HUMAN
• UniProt AC: Q8NDM7
• Protein Name: Cilia- and flagella-associated protein 43 {ECO:0000312|HGNC:HGNC:26684}
• Gene Name: CFAP43 {ECO:0000312|HGNC:HGNC:26684}
• Organism: Homo sapiens (Human).
• Sequence Length: 1665
• Subcellular Localization: Cell projection, cilium, flagellum .
• Protein Sequence: MAQGRERDEGPHSAGGASLSVRWVQGFPKQNVHFVNDNTICYPCGNYVIFINIETKKKTVLQCSNGIVGVMATNIPCEVVAFSDRKLKPLIYVYSFPGLTRRTKLKGNILLDYTLLSFSYCGTYLASYSSLPEFELALWNWESSIILCKKSQPGMDVNQMSFNPMNWRQLCLSSPSTVSVWTIERSNQEHCFRARSVKLPLEDGSFFNETDVVFPQSLPKDLIYGPVLPLSAIAGLVGKEAETFRPKDDLYPLLHPTMHCWTPTSDLYIGCEEGHLLMINGDTLQVTVLNKIEEESPLDRRNFISPVTLVYQKEGVLASGIDGFVYSFIIKDRSYMIEDFLEIERPVEHMTFSPNYTVLLIQTDKGSVYIYTFGKEPTLNKVLDACDGKFQAIDFITPGTQYFMTLTYSGEICVWWLEDCACVSKIYLNTLATVLACCPSSLSAAVGTEDGSVYFISVYDKESPQVVHKAFLSESSVQHVVYDQQGIFLLVGTAEGKVFIINANSSSSFQIIGFTEVAKDILQISTVSLLETDIVEVMVLSSLPEAGRSRLEMFTLPTLLPQVSTTFADERGRLKDEIIHKYLYELEHALSSAVLGFQSNQIYGFCSQVPYICSYLLPEEEHTGIYILKPYKKVQSRQYGPGLLYLSSHGLWLITIAKCGILCIRDVYTLETFAWCRSHSHQGHGIQSMRISMDGQNILVNGRDDGTLVYLKWKRFGGHLASEILDYYQKLLISLSSAMDKENHYLSTTPKVSVDLGSDSEHTKQKASTDLSQDELVLTDVKKEIPWIQQKSQEAIKKEVNLFSKKRKEIKQGIKSLSKTILNMMEENDKLENIAKLDQQEFGLDLEELERLHDESQEEVAKMIKDVEMHNLAKSYLAELIKEECWNSMAVKGRALKCFHIPCVVENFPMKARTVEELKELERVLQQKKIEAECLKLRKEIVEAQSGVKLIKQRHEEDDEEEEEEDKTVKYSNLPNYLLGSLSTDFGVDTSLLSSQLELHSREEKINQIILLKDIIYKVKTVFNNEFDAAYKQKEFEIARVKERNVRIREIILDLELEEAVWQPEFEDCEKPERTLVVQDEEITAHKHIKPWHKAKELIVNHEKEHWLLIQDASTRLRALMDMMGGVLEVKKEDILRMVIPQPAFMAKPDAVWTEEERKQFKDYEKKVKELNEERDKYRKSLEAELKKLQNSIQESTQAFDEHLKRLFERRVKAEMVTNQEELKISNLAFSLLLDEELSSREKFLNNYLTRKQHEKSQTSEAVRKSREDLDVCKEHYDNLLAEDKVMDRSFKKEFSEIPGHQVDILYKLFKRRPRISKQKTHSETTSVVPFGELPGSGKLNKDAFAQLMKAMDELDNISNMPEGLDPLVWNHFCMTRRAKVENEQKVKQKAADLLEMATFLQKRVEEEEKVQQEIERVFHELILLQEEKVRFQLNLTIQILLKQGQVELENFQLVLEYSDAILINKNIIEDLNSVIRTQGQKKVASMMESKDVHKRILQIEWEHKKMEMEREDLNQKAWDIQMLFFSRDRQKYLNEPNYEALISIQIGIMEQTIAVLDKMHKKNVENCKKLLKKLGKFSNQKDIANYALSCNLREELVAVSERKDICNAMGSKLTCEKIVKERYENMMQQQKLTNISKQQAEQISILQTEVERLRMKTFPALVQM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	SAGGASLSVRWVQGF CCCCCEEEEEEECCC		24719451
22	Methylation	GGASLSVRWVQGFPK CCCEEEEEEECCCCC		24395769
326	Phosphorylation	SGIDGFVYSFIIKDR ECCCEEEEEEEECCC		-
327	Phosphorylation	GIDGFVYSFIIKDRS CCCEEEEEEEECCCC		-
367	Phosphorylation	LIQTDKGSVYIYTFG EEEECCCEEEEEEEC		-
728	Phosphorylation	ASEILDYYQKLLISL HHHHHHHHHHHHHHH		-
734	Phosphorylation	YYQKLLISLSSAMDK HHHHHHHHHHHHCCC		23403867
736	Phosphorylation	QKLLISLSSAMDKEN HHHHHHHHHHCCCCC		23403867
737	Phosphorylation	KLLISLSSAMDKENH HHHHHHHHHCCCCCC		23403867
768	Phosphorylation	EHTKQKASTDLSQDE HHHHHHHCCCCCCCC		30622161
769	Phosphorylation	HTKQKASTDLSQDEL HHHHHHCCCCCCCCE		30622161
772	Phosphorylation	QKASTDLSQDELVLT HHHCCCCCCCCEEHH		30622161
804	Phosphorylation	KKEVNLFSKKRKEIK HHHHHHHHHHHHHHH		24719451
946	Phosphorylation	KEIVEAQSGVKLIKQ HHHHHHHHHHHHHHH		-
1205	Acetylation	QAFDEHLKRLFERRV HHHHHHHHHHHHHHH		25038526
1226	Phosphorylation	NQEELKISNLAFSLL CHHHHHHHHHHHHHH		-
1231	Phosphorylation	KISNLAFSLLLDEEL HHHHHHHHHHHCHHH		-
1248	Phosphorylation	REKFLNNYLTRKQHE HHHHHHHHHHHHHHH		19664994
1250	Phosphorylation	KFLNNYLTRKQHEKS HHHHHHHHHHHHHHH		30619164
1327	Phosphorylation	KTHSETTSVVPFGEL CCCCCCCEEEECCCC		-
1337	Phosphorylation	PFGELPGSGKLNKDA ECCCCCCCCCCCHHH		30622161
1390	Ubiquitination	NEQKVKQKAADLLEM CHHHHHHHHHHHHHH		-
1482	Methylation	VIRTQGQKKVASMME HHHHHCHHHHHHHHH		-
1569	Acetylation	KKNVENCKKLLKKLG HHCHHHHHHHHHHHC		19810231
1634	Phosphorylation	MMQQQKLTNISKQQA HHHHHHHHCCCHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CFA43_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CFA43_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CFA43_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CFA43_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.