CEPT1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CEPT1_MOUSE
• UniProt AC: Q8BGS7
• Protein Name: Choline/ethanolaminephosphotransferase 1
• Gene Name: Cept1
• Organism: Mus musculus (Mouse).
• Sequence Length: 416
• Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.
• Protein Description: Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP-ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity (By similarity)..
• Protein Sequence: MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVGRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIPVLNIQMKLLPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALIFSFFDLIRYCVSVCNQIASHLHIHVFRIKASTAHSNHH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	TRKRCGDSHPESPVG CCCCCCCCCCCCCCC	26.65	25159016
18	Phosphorylation	CGDSHPESPVGFGHM CCCCCCCCCCCCCCC	29.36	25159016
26	Phosphorylation	PVGFGHMSTTGCVLN CCCCCCCCCCCHHHH	19.69	29472430
27	Phosphorylation	VGFGHMSTTGCVLNK CCCCCCCCCCHHHHH	21.45	29472430
28	Phosphorylation	GFGHMSTTGCVLNKL CCCCCCCCCHHHHHH	22.68	26643407
40	Phosphorylation	NKLFQLPTPPLSRHQ HHHHCCCCCCCCHHH	46.24	26745281
44	Phosphorylation	QLPTPPLSRHQLKRL CCCCCCCCHHHHHHH	33.23	26643407
144	N-linked_Glycosylation	GKQARRTNSSSPLGE CCHHCCCCCCCCHHH	37.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CEPT1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CEPT1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CEPT1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CEPT1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.