CEP97_MOUSE - dbPTM
CEP97_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CEP97_MOUSE
UniProt AC Q9CZ62
Protein Name Centrosomal protein of 97 kDa
Gene Name Cep97
Organism Mus musculus (Mouse).
Sequence Length 856
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
Protein Description Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome (By similarity)..
Protein Sequence MAVARVDGALAPGEGSVVNWSGQGLQKLGANLPCEADVHTLILDKNQIIKLENLEKCKQLIQLSVANNRLVRMMGVAKLTQLRVLNLPHNSIGCVEGLKDLVHLEWLNLAGNNLKTMEQVNSCTALQHLDLSDNNIPQIGDVSKLISLKTLLLHGNIITSLRMAPAYLPRNLSILSLAENEIRDLNEISFLASLSELEQLSIMNNPCVMATPSIPGFDYRPFIVSWCLNLRVLDGYVISQKESLKAEWLYSQGKGRSYRPGQHIQLVQYLATVCPLTSALGLQTAEDAKLEKILSKQRFHQRQLMSQSQDEELSPLAAVETRVHRTPECSSPGQDFQESEPVLQINSWVGISSNDDQLYAVKNNFPAAAHAARYSRNDLHLEDIQTDEDKLNCSLLSSESTFMPVASGLSPVSPTVELRLQGINLGLEDDDGADEFTKGLENQDEDKDKEKSLWDMSESCVEMLKRKISTEVSEAAGLLPCPKSVIISAALKEDTHSLTSLPESAGHSASRTEANSEEAMSPATSEKFPCRILTQRPAALGQDKVTLQKLNAAATKLQACWRGFYTRNYNQQAKGVRYEIRLRRMQEHIVCLTDEVRRLRKERDEERVKTFVQEEAVRFLWNEVRSVQAWQQTVEQRLASWPPDVPPISSTLASPKPPLFPHHQDPSSDQSSDWLVAEDEAAQGRSAPDFPDSGFHSSLTEQVPCLQDSLDFEKSSVESSENSVLGNSADTVKCVKDRDSEATAEEHSDCSRESSASEQDNTLLQQYLTSVQQLDDAAEAADSDDVAGDGKRHLACSPERFDASSDSETHRVASTSQDEISQTPENCQLNEEAQGQPPECDPAFQGLHVGVTVQPV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
147PhosphorylationGDVSKLISLKTLLLH
CCHHHHHCHHHHHHC		33.9624719451
306PhosphorylationFHQRQLMSQSQDEEL
HHHHHHHHCCCCCCC		34.9625266776
308PhosphorylationQRQLMSQSQDEELSP
HHHHHHCCCCCCCCH		32.0925266776
314PhosphorylationQSQDEELSPLAAVET
CCCCCCCCHHHHHHE		22.5825338131
374PhosphorylationAAAHAARYSRNDLHL
HHHHHHHHCCCCCCH		13.7818846507
375PhosphorylationAAHAARYSRNDLHLE
HHHHHHHCCCCCCHH		21.0322817900
397PhosphorylationKLNCSLLSSESTFMP
HHCCCCCCCCCCCCC		37.0325293948
398PhosphorylationLNCSLLSSESTFMPV
HCCCCCCCCCCCCCC		35.2225293948
400PhosphorylationCSLLSSESTFMPVAS
CCCCCCCCCCCCCCC		28.9725293948
401PhosphorylationSLLSSESTFMPVASG
CCCCCCCCCCCCCCC		21.6525293948
407PhosphorylationSTFMPVASGLSPVSP
CCCCCCCCCCCCCCC		40.2723984901
410PhosphorylationMPVASGLSPVSPTVE
CCCCCCCCCCCCCEE		27.1226643407
413PhosphorylationASGLSPVSPTVELRL
CCCCCCCCCCEEEEE		20.4526643407
415PhosphorylationGLSPVSPTVELRLQG
CCCCCCCCEEEEECC		21.0726643407
469PhosphorylationEMLKRKISTEVSEAA
HHHHHHHCHHHHHHC		22.8825266776
470PhosphorylationMLKRKISTEVSEAAG
HHHHHHCHHHHHHCC		43.8326160508
473PhosphorylationRKISTEVSEAAGLLP
HHHCHHHHHHCCCCC		18.4525266776
495PhosphorylationSAALKEDTHSLTSLP
HHHHHCCCCCCCCCC		17.9218846507
497PhosphorylationALKEDTHSLTSLPES
HHHCCCCCCCCCCCC		35.1222817900
499PhosphorylationKEDTHSLTSLPESAG
HCCCCCCCCCCCCCC		31.0918846507
500PhosphorylationEDTHSLTSLPESAGH
CCCCCCCCCCCCCCC		47.4118846507
504PhosphorylationSLTSLPESAGHSASR
CCCCCCCCCCCCCCC		37.3025338131
521PhosphorylationANSEEAMSPATSEKF
CCCHHHCCHHHCCCC		20.5925619855
524PhosphorylationEEAMSPATSEKFPCR
HHHCCHHHCCCCCCE		40.5825619855
525PhosphorylationEAMSPATSEKFPCRI
HHCCHHHCCCCCCEE		40.6825619855
534PhosphorylationKFPCRILTQRPAALG
CCCCEEECCCCCCCC		21.84-
654PhosphorylationPISSTLASPKPPLFP
CCCCCCCCCCCCCCC		36.2527149854
715PhosphorylationDSLDFEKSSVESSEN
HHCCCCHHHHHCCCC		32.2125293948
716PhosphorylationSLDFEKSSVESSENS
HCCCCHHHHHCCCCC		40.7625293948
719PhosphorylationFEKSSVESSENSVLG
CCHHHHHCCCCCCCC		40.5725293948
720PhosphorylationEKSSVESSENSVLGN
CHHHHHCCCCCCCCC		27.5625293948
723PhosphorylationSVESSENSVLGNSAD
HHHCCCCCCCCCCHH		18.0525293948
740PhosphorylationKCVKDRDSEATAEEH
EEECCCCCCHHHHHH		29.9929899451
748PhosphorylationEATAEEHSDCSRESS
CHHHHHHCCCCCCCC		43.5229899451
754PhosphorylationHSDCSRESSASEQDN
HCCCCCCCCCHHHHH		30.0525293948
755PhosphorylationSDCSRESSASEQDNT
CCCCCCCCCHHHHHH		30.9425293948
757PhosphorylationCSRESSASEQDNTLL
CCCCCCCHHHHHHHH		37.4325293948
762PhosphorylationSASEQDNTLLQQYLT
CCHHHHHHHHHHHHH		36.8225293948
797PhosphorylationGKRHLACSPERFDAS
CCCEEEECHHHCCCC		24.9626824392
804PhosphorylationSPERFDASSDSETHR
CHHHCCCCCCHHHCC		36.2028833060
805PhosphorylationPERFDASSDSETHRV
HHHCCCCCCHHHCCC		47.0426824392
807PhosphorylationRFDASSDSETHRVAS
HCCCCCCHHHCCCCC		46.4728833060
809PhosphorylationDASSDSETHRVASTS
CCCCCHHHCCCCCCC		20.9528833060
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CEP97_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CEP97_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CEP97_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CEP97_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CEP97_MOUSE

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Related Literatures of Post-Translational Modification

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