dbPTM

CED12_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CED12_CAEEL
UniProt AC	Q8STE5
Protein Name	Cell death abnormality protein 12 {ECO:0000303\|PubMed:11703939}
Gene Name	ced-12 {ECO:0000312\|EMBL:AAL38510.1}
Organism	Caenorhabditis elegans.
Sequence Length	731
Subcellular Localization	Cytoplasm . Punctate localization.
Protein Description	Involved in programmed apoptosis and necrosis. Required for the cell corpse engulfment process. Has roles in the formation of actin halos and distal tip cell migration. [PubMed: 11703939]
Protein Sequence	MAFHMPLKELQPVDTSLPEHVVKGAVVIDKEFTIWNHRAVIPSNALHTVFITINLLEQKLTDVVKMAARSMNLSEDDSYGLMADKPKRFITDDNLNSLGSGFILTLCASPDHYVKRITEILTEGNNISQMENAVKTLDEFSLDPALIEAFYRCSSLELLFSLIRDDRVCMSSTLLSTCLRALSSMLELAVGDFTWKSVPNDVVVSMASLVTGKAKREEANTLLAALQMLEQLVIGDDTTRDWILEEVPIETLIRHVEKSDERIALCALSLMNSMIRRCPDDEKRFELIKSLEVVPFRNAVHSSLLRGGGGVRNLNAIEQLVEVQRSLISAYETSPPTDAEVQKILDIESSEDVSEEIREMWKSQIGEHRCGRLAAISMVQFAEKSPQDLRMLISENTMRIEGGKWQLIPMWMRCCDIAAELFRVIPGRDELDRLIVVLFSTETPFPAVFACIVHLFHRTWREMQAKGGEMEKVACVVLEQLRHVLKRREIQDVEELSADLETFSYRAMQEIWREEQLGKENIQLHSEAVIQLKSKLRPKMEELVRINHLNYLKLGAVFRKPQKSKSLAKLAFWHWKLDASEKMLTITGCDGENYVEGVQRDDIRQVWIKDIADVTNNDEIDRKASSSRFTSSPSTQMLRGIRVQLKTTNDMKEGEVLMALTSDETQSVIWLEGLAELIGSKAVKSETDAMVERMLKMELRVRLLNVKLTNPEEKPEIPPIPDDIKSFISKF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of CED12_CAEEL !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CED12_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CED12_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CED12_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
JMJD6_CAEEL	psr-1	genetic	14645848
JMJD6_CAEEL	psr-1	physical	14645848

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CED12_CAEEL

Related Literatures of Post-Translational Modification