CECR2_HUMAN - dbPTM
CECR2_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CECR2_HUMAN
UniProt AC Q9BXF3
Protein Name Cat eye syndrome critical region protein 2
Gene Name CECR2
Organism Homo sapiens (Human).
Sequence Length 1484
Subcellular Localization
Protein Description Chromatin reader component of histone-modifying complexes, such as the CERF (CECR2-containing-remodeling factor) complex and ISWI-type complex. [PubMed: 15640247]
Protein Sequence MCPEEGGAAGLGELRSWWEVPAIAHFCSLFRTAFRLPDFEIEELEAALHRDDVEFISDLIACLLQGCYQRRDITPQTFHSYLEDIINYRWELEEGKPNPLREASFQDLPLRTRVEILHRLCDYRLDADDVFDLLKGLDADSLRVEPLGEDNSGALYWYFYGTRMYKEDPVQGKSNGELSLSRESEGQKNVSSIPGKTGKRRGRPPKRKKLQEEILLSEKQEENSLASEPQTRHGSQGPGQGTWWLLCQTEEEWRQVTESFRERTSLRERQLYKLLSEDFLPEICNMIAQKGKRPQRTKAELHPRWMSDHLSIKPVKQEETPVLTRIEKQKRKEEEEERQILLAVQKKEQEQMLKEERKRELEEKVKAVEGMCSVRVVWRGACLSTSRPVDRAKRRKLREERAWLLAQGKELPPELSHLDPNSPMREEKKTKDLFELDDDFTAMYKVLDVVKAHKDSWPFLEPVDESYAPNYYQIIKAPMDISSMEKKLNGGLYCTKEEFVNDMKTMFRNCRKYNGESSEYTKMSDNLERCFHRAMMKHFPGEDGDTDEEFWIREDEKREKRRSRAGRSGGSHVWTRSRDPEGSSRKQQPMENGGKSLPPTRRAPSSGDDQSSSSTQPPREVGTSNGRGFSHPLHCGGTPSQAPFLNQMRPAVPGTFGPLRGSDPATLYGSSGVPEPHPGEPVQQRQPFTMQPPVGINSLRGPRLGTPEEKQMCGGLTHLSNMGPHPGSLQLGQISGPSQDGSMYAPAQFQPGFIPPRHGGAPARPPDFPESSEIPPSHMYRSYKYLNRVHSAVWNGNHGATNQGPLGPDEKPHLGPGPSHQPRTLGHVMDSRVMRPPVPPNQWTEQSGFLPHGVPSSGYMRPPCKSAGHRLQPPPVPAPSSLFGAPAQALRGVQGGDSMMDSPEMIAMQQLSSRVCPPGVPYHPHQPAHPRLPGPFPQVAHPMSVTVSAPKPALGNPGRAPENSEAQEPENDQAEPLPGLEEKPPGVGTSEGVYLTQLPHPTPPLQTDCTRQSSPQERETVGPELKSSSSESADNCKAMKGKNPWPSDSSYPGPAAQGCVRDLSTVADRGALSENGVIGEASPCGSEGKGLGSSGSEKLLCPRGRTLQETMPCTGQNAATPPSTDPGLTGGTVSQFPPLYMPGLEYPNSAAHYHISPGLQGVGPVMGGKSPASHPQHFPPRGFQSNHPHSGGFPRYRPPQGMRYSYHPPPQPSYHHYQRTPYYACPQSFSDWQRPLHPQGSPSGPPASQPPPPRSLFSDKNAMASLQGCETLNAALTSPTRMDAVAAKVPNDGQNPGPEEEKLDESMERPESPKEFLDLDNHNAATKRQSSLSASEYLYGTPPPLSSGMGFGSSAFPPHSVMLQTGPPYTPQRPASHFQPRAYSSPVAALPPHHPGATQPNGLSQEGPIYRCQEEGLGHFQAVMMEQIGTRSGIRGPFQEMYRPSGMQMHPVQSQASFPKTPTAATSQEEVPPHKPPTLPLDQS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
104PhosphorylationPNPLREASFQDLPLR
CCCCCCCCCCCCCHH		20.77-
165PhosphorylationYFYGTRMYKEDPVQG
EEECCEEEECCCCCC		14.1328122231
174PhosphorylationEDPVQGKSNGELSLS
CCCCCCCCCCEEEEC		57.8229978859
179PhosphorylationGKSNGELSLSRESEG
CCCCCEEEECCCCCC		21.7224719451
181PhosphorylationSNGELSLSRESEGQK
CCCEEEECCCCCCCC		30.5329116813
196AcetylationNVSSIPGKTGKRRGR
CCCCCCCCCCCCCCC		49.0712430219
199AcetylationSIPGKTGKRRGRPPK
CCCCCCCCCCCCCCC		44.1230587575
217PhosphorylationLQEEILLSEKQEENS
HHHHHHHCHHHHHHC		39.0224719451
239PhosphorylationRHGSQGPGQGTWWLL
CCCCCCCCCCCEEEE		45.43-
335PhosphorylationKQKRKEEEEERQILL
HHHHHHHHHHHHHHH		67.27-
338PhosphorylationRKEEEEERQILLAVQ
HHHHHHHHHHHHHHH		31.92-
363PhosphorylationERKRELEEKVKAVEG
HHHHHHHHHHHHHHH		75.64-
388PhosphorylationACLSTSRPVDRAKRR
HHHCCCCCCCHHHHH		31.93-
422PhosphorylationLSHLDPNSPMREEKK
HHCCCCCCCCCCCHH		26.0119664995
506PhosphorylationFVNDMKTMFRNCRKY
HHHHHHHHHHHHHHH		2.18-
513PhosphorylationMFRNCRKYNGESSEY
HHHHHHHHCCCCCCC		14.73-
517MethylationCRKYNGESSEYTKMS
HHHHCCCCCCCCCCC		29.84-
517PhosphorylationCRKYNGESSEYTKMS
HHHHCCCCCCCCCCC		29.8422210691
518PhosphorylationRKYNGESSEYTKMSD
HHHCCCCCCCCCCCH		30.2518491316
520MethylationYNGESSEYTKMSDNL
HCCCCCCCCCCCHHH		17.38-
521PhosphorylationNGESSEYTKMSDNLE
CCCCCCCCCCCHHHH		19.0718491316
527MethylationYTKMSDNLERCFHRA
CCCCCHHHHHHHHHH		5.43-
546PhosphorylationFPGEDGDTDEEFWIR
CCCCCCCCCHHCCCC		51.3330266825
568PhosphorylationRRSRAGRSGGSHVWT
HHHHCCCCCCCCCCC		46.7321406692
571PhosphorylationRAGRSGGSHVWTRSR
HCCCCCCCCCCCCCC		20.5621406692
600PhosphorylationGGKSLPPTRRAPSSG
CCCCCCCCCCCCCCC		30.74-
605PhosphorylationPPTRRAPSSGDDQSS
CCCCCCCCCCCCCCC		46.0721406692
606PhosphorylationPTRRAPSSGDDQSSS
CCCCCCCCCCCCCCC		45.2221406692
611PhosphorylationPSSGDDQSSSSTQPP
CCCCCCCCCCCCCCC		38.9021406692
612PhosphorylationSSGDDQSSSSTQPPR
CCCCCCCCCCCCCCC		23.7521406692
613PhosphorylationSGDDQSSSSTQPPRE
CCCCCCCCCCCCCCC		42.5221406692
614PhosphorylationGDDQSSSSTQPPREV
CCCCCCCCCCCCCCC		32.7721406692
615PhosphorylationDDQSSSSTQPPREVG
CCCCCCCCCCCCCCC		47.2221406692
623PhosphorylationQPPREVGTSNGRGFS
CCCCCCCCCCCCCCC		24.9721406692
624PhosphorylationPPREVGTSNGRGFSH
CCCCCCCCCCCCCCC		31.2121406692
640MethylationLHCGGTPSQAPFLNQ
CCCCCCHHHCHHHHH		38.52-
649MethylationAPFLNQMRPAVPGTF
CHHHHHCCCCCCCCC		13.28-
689PhosphorylationVQQRQPFTMQPPVGI
CCCCCCCCCCCCCCC		22.9122210691
698PhosphorylationQPPVGINSLRGPRLG
CCCCCCCCCCCCCCC		19.9530631047
700MethylationPVGINSLRGPRLGTP
CCCCCCCCCCCCCCH		53.54-
703MethylationINSLRGPRLGTPEEK
CCCCCCCCCCCHHHH		48.88-
708MethylationGPRLGTPEEKQMCGG
CCCCCCHHHHHHCCC		77.11-
710MethylationRLGTPEEKQMCGGLT
CCCCHHHHHHCCCCH		41.49-
823MethylationPGPSHQPRTLGHVMD
CCCCCCCCCHHHCCC		35.69-
824PhosphorylationGPSHQPRTLGHVMDS
CCCCCCCCHHHCCCC		43.7221406692
829PhosphorylationPRTLGHVMDSRVMRP
CCCHHHCCCCCCCCC		3.00-
830PhosphorylationRTLGHVMDSRVMRPP
CCHHHCCCCCCCCCC		32.00-
831PhosphorylationTLGHVMDSRVMRPPV
CHHHCCCCCCCCCCC		14.5321406692
832MethylationLGHVMDSRVMRPPVP
HHHCCCCCCCCCCCC		23.22-
836PhosphorylationMDSRVMRPPVPPNQW
CCCCCCCCCCCCCCC		19.02-
880PhosphorylationPPPVPAPSSLFGAPA
CCCCCCCHHHCCCHH		41.6021082442
881PhosphorylationPPVPAPSSLFGAPAQ
CCCCCCHHHCCCHHH		27.0221082442
891MethylationGAPAQALRGVQGGDS
CCHHHHHHCCCCCCC		46.37-
898PhosphorylationRGVQGGDSMMDSPEM
HCCCCCCCCCCCHHH		21.20-
1013PhosphorylationQTDCTRQSSPQERET
CCCCCCCCCHHHHHC		40.4728450419
1014PhosphorylationTDCTRQSSPQERETV
CCCCCCCCHHHHHCC		23.4328450419
1020PhosphorylationSSPQERETVGPELKS
CCHHHHHCCCHHHCC		36.6621406692
1073PhosphorylationVADRGALSENGVIGE
HHHHCCCCCCCCCCC		28.6021406692
1082PhosphorylationNGVIGEASPCGSEGK
CCCCCCCCCCCCCCC		19.2019664995
1086PhosphorylationGEASPCGSEGKGLGS
CCCCCCCCCCCCCCC		50.3130266825
1128PhosphorylationPPSTDPGLTGGTVSQ
CCCCCCCCCCCCHHH		4.97-
1197MethylationSGGFPRYRPPQGMRY
CCCCCCCCCCCCCCC		37.39-
1203MethylationYRPPQGMRYSYHPPP
CCCCCCCCCCCCCCC		24.87-
1248PhosphorylationSPSGPPASQPPPPRS
CCCCCCCCCCCCCCC		49.33-
1251MethylationGPPASQPPPPRSLFS
CCCCCCCCCCCCCCC		43.84-
1255PhosphorylationSQPPPPRSLFSDKNA
CCCCCCCCCCCCHHH		39.2721815630
1259MethylationPPRSLFSDKNAMASL
CCCCCCCCHHHHHHH		40.68-
1276MethylationCETLNAALTSPTRMD
HHHHHHHHCCCCCHH		4.53-
1277PhosphorylationETLNAALTSPTRMDA
HHHHHHHCCCCCHHH		28.1224275569
1306PhosphorylationEEEKLDESMERPESP
HHHHHHHHHCCCCCH		26.1322496350
1312PhosphorylationESMERPESPKEFLDL
HHHCCCCCHHHHHCC		43.9111214970
1435MethylationIGTRSGIRGPFQEMY
HCCCCCCCCCHHHCC		50.70-
1443MethylationGPFQEMYRPSGMQMH
CCHHHCCCCCCCCCC		20.00-
1460MethylationQSQASFPKTPTAATS
CCCCCCCCCCCCCCC		66.19-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CECR2_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CECR2_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CECR2_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CECR2_HUMAN !!
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CECR2_HUMAN

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Related Literatures of Post-Translational Modification

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