dbPTM

CE042_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CE042_MOUSE
UniProt AC	Q8CE72
Protein Name	Protein JBTS17 {ECO:0000303\|PubMed:25877302, ECO:0000303\|PubMed:27158779}
Gene Name	Jbts17 {ECO:0000303\|PubMed:25877302}
Organism	Mus musculus (Mouse).
Sequence Length	3214
Subcellular Localization	Membrane Multi-pass membrane protein . Cell projection, cilium . Localizes to the ciliary transition zone.
Protein Description	Involved in ciliogenesis. Involved in the establishment of cell polarity required for directional cell migration. [PubMed: 25877302 Proposed to act in association with the CPLANE (ciliogenesis and planar polarity effectors) complex. Involved in recruitment of peripheral IFT-A proteins to basal bodies]
Protein Sequence	MEMRLEVLTSTSIKQKKPWPRVSWLGQENEAVFLLDEKFINEINLLSGRTKKKIPSLQPLLKDVVFLATSTNDVWLSGVLTTGELFLWNKDQDCLKKIHVTEKPKEAIKAAVASSSRLYLYVAENGKRILLITSSGCILLWEYLELKNILSSKSLSLVGQWSQIVPEEAVSLPSTKDKEAVVAAVFVKNELLGDCCLCSFTFYSGECLKLTFLDIQWYENIFTSVRSLLFRVHWAQQECPLCSLIPRCASVKSRGALISAFSRDGLALAVTLNQKDPTATQVLFINTLNFVTLCGGLKGCSNKNPVVPATLTRSYWVGDISWTHDSLFLTCVLKRGSLVLLTCLGELLTLVTFGCSIEFGPAEFIPLHPLITYRPQQLPFQDSNNCVDSSASESDPLRQRFSIKAHSRLPYLIISDGYMVTTLRFLDNQSPTMLMRSLLLDSTQRLEKAYQSMMLSEPKDKGLNFRSLDSLRSSLLKHQGKESSVHCTVPRFLQAEETMKLNETTDFQDFEGEETNEVEQFVNNSFSFCNQKKDLPFDIVKEGRLEFASMFDTVHAKDASKETDRNTAELHRIQKTLLAAWTIGISKNVTEKKLMLNYTILCITHFFYILQFIKCPVPKFDLFLNKSLKRNAWVLCVFQLFHQCLSVHYWDMRYRQNMGHLIRLTANTVKLLLTQRQEHGSFSERLLACLSLLRTVTVHLNGTCSLQPEAVPAAADESRPAELDSLMVPIFQASKENWPWDSSLKIYPQVTNLVQKPGHRLIALWRLLYKKTLWYQAQLSQRTPDGDRRLTENIRHEVSVVKTLLCHVQTNLQMAGDSLNQALELTPISGEECFLLASYEKSVCLWKKALQETQEKGGRRTCFLQLRYYLSLLYCHLYCYNLNDAQGLCDHLVRELLSRSQLPVRESQDCSDCEIAVTGNVHPEAALRVVQCMARFMAAYFTNEPLFILPPHSVSVLPPLHVKTEHSLRLIPLQHSKVASVIRDQNLSNVWTVEYTLELLFIGGLIPEAVWMAHKLGDWKTSVSIGVAYQVFCKHDCNFARSKKKGMDLPLNMIPAQIFQEKLQCFLGQPVSLTKKNEKGSKYKQFTDPIEEEDASLLFGSVQEVLKASVMADADIVSETLQLLMDSAKDFSKKLWGLVPVDLYLPAPPLYCPQPAVLSEEHGDNLLLKAEKDNRQKLSGILQRVLLLFRASRCSFPVAQWYILQLRWARKVMQKIRVKGSLPSLGSFPESLLNYCKGGIAFFRPGATGDHTLDEVSIKALGCFRELCALCWMLHVRDKLSYTCRQYQKARENTKIEKDLEVGFDSCVVEHCFHALEWACRMLPFSRFFNMEELIQDIILSLIGELPPIRKVAEIFVKAFPNPEAIRVPLREKYHSLQQKLKHGVVKGPQTEELMSTVMRHVRKVRVKALKRVQRNIGAFEMDIWEPDEEDKPAATPAADRFSLGPSVSSTLTLDLGSSLLHSDADTFSETLSLEEKTWIHLYQRHTPSHMELALVGKKPSDKKKVSNQKENSQRKEDDETPGKEALPVIGVWEFERDDDEYISFLELFLSYILERDLCSSDPGIPFLTSFSGRLREHELNSLLFDVHTTLKRRQSKTISENVYRAGSCFAVTPESQEPENLSSLNSVGARHFESQALSASALGNQSGSTLENPLQSGSTSENPLQSDVMNWERRAGLFGLKQKPMYRVPDDKREKPTVQRSSNHSFWVPESIKPGRHRFRALEGSAGPPREDLPLALQSMFGDAGRLVEWMIRWSDRRLLCDPGVTPSSCKYSPVIRVKTSTAAILTSLWLLEQPYSAAYTAKNGIIKVLERHHTEPQVAAERESDVDADCPAAVAAQEGTECWNRMPAEAENHDVKDTGDEIAPVTPGSERELVHADGRHSEAGSSTQDEMDVHISDSEEGPVESLRGPSAVICRPESQLSSEHSEEEAQCSRKEPRDASVDTNLTEQKGAQISDLKEKSPTVLPLMSNGAQDTSQTPQKTQGNEHRAQLPDASESVRQMLQDEMFKLVQLQQINFLSLMQIVGPSVASLPDMHGLLQQAQSVRFGESQVSNSTKSDCIEVNSRQRVSARAQSMGECTREPGKNSPADHKRISRPDQDSSGDTQDIPHGSVPLCQLDGQPEVRGQTGAPRSFAPASFPPAPAADSGLQLLFTPAAIQKTPQLIPPARAGAPGRGFPLLHFQPKRDFKPLSLPVGRIPQVSFRPQAQPKEAWSLSDSCQPPVSQRTVHTTLPSPSDSSHCNAEAMRKAEAVLTGIPKHVNMGQYAGQGYLTPQQDSSVFIKPENVFDVKPSPPETALQNSFGLPLLHLQFKPPYVFSAPPRAFSRFPSVPGTEGRNQPQLSLLHPCLPPENTYKKPQLIPLENLLAFKRSQQKLAHSVSGQGDAAPHFVGVSMDAAGITQGKQRQSRRAKRELQEGRAQKPRRKPNVSFRPEDSLISNDSEVIIEPKEQLGHHDSQHLDKFDIPFEMLEDDINTSAGLHFMASVRKKAVGSHDASTNTDPDKEGPSQKADSESSKNPQATAASSGHEPLKVPQLLIPDIYLNVRLPSGIAEKPLSPSPPHMAGHKYIDVVDIEADDLLGLPACEEPSDEVTKQQSHPPHAPSSAELHCMAASIVDAAPPHTFQSQESASSTRGLISEPAKVTQSCQSGESWRKSVIEAKEPEIPSVAPPSDRQQDRDILEQNFQFKEQSTKLDSVGQSLLWTLLQNASPACPTPSPAVCPRPSSPACPPPSPAVCPPPSPAACPTPSPAAQKFEHLTAKLQEMDEQLVAVQTMAENIEQDFPASQVLNLHWEKAGLGNHVGLSSGPDIEKLLASKAISISEEVSLQTQEDVEEQKDAEETSETEFSEAENHSSQKTYACPSVGSAACSSVGWNIPSPGLNDSNELLESGSEDQLQVTGLTDIADIIGDLITKSGVSSHELGLTECQARSISRIQRPPDRGPRRTAEERREIKAWMRRKQKERMSEYLGQLAERRGRERNPFCPTSSPFYMTSRQIRQRQKMKREKDRLQLSKHYSQRLSQAYSLMNELLSDSAHITAPAENPLPPGPYRRQRGSSPKRENAHGQSLPVNRPGGDRHISRSSHLCKGQPRGSSQLRGSQPPCQSQKPLRSRGAAGVGPPVQQACREDEREEMVVSPWTLPSEIHRILHGRPESLLQDMSPADEEEPEPPLLAGGMDSVSESTGSILSKLDWKAVEDMVASVEDKNLSVHWALDQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of CE042_MOUSE !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CE042_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CE042_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CE042_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CE042_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CE042_MOUSE

Related Literatures of Post-Translational Modification