CDV3_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CDV3_DROME
• UniProt AC: Q8MMC4
• Protein Name: Protein CDV3 homolog
• Gene Name: CG3760
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 271
• Protein Sequence: MAELDDFFAKKDKKKSKNKTKFVTADEMVKNLEDGTKREVVKPKKPEVAAGGVAVVGENENSGTKVPESAPPVEEEWKEFEEEQRKDYSGLKIGQLSTISSARSRTAQESSESQAARVPSAPDGGNYNEDDEDSNGYDNADVNKERVGHGPWKKVVPAEEVMQIPVPVEVEKHSSKTYVSPALRYSQQAGSGLGGGPTGGALRPRRAAPDITNTEFFPTLSAARPEEQRKKKNEPAFEEVRHGSRFQRVQESTAAPVAASNRFQSLDDEAS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Acetylation	ELDDFFAKKDKKKSK CHHHHHHHHCHHCCC	57.24	21791702
36	Phosphorylation	VKNLEDGTKREVVKP HHCCCCCCCCEEECC	38.97	22817900
97	Phosphorylation	GLKIGQLSTISSARS CCCHHHHHHHHCHHC	18.79	21082442
98	Phosphorylation	LKIGQLSTISSARSR CCHHHHHHHHCHHCC	33.21	21082442
101	Phosphorylation	GQLSTISSARSRTAQ HHHHHHHCHHCCCCH	24.69	21082442
120	Phosphorylation	SQAARVPSAPDGGNY HHHHCCCCCCCCCCC	49.96	22817900
134	Phosphorylation	YNEDDEDSNGYDNAD CCCCCCCCCCCCCCC	30.06	21082442
137	Phosphorylation	DDEDSNGYDNADVNK CCCCCCCCCCCCCCH	15.41	19429919
180	Phosphorylation	HSSKTYVSPALRYSQ CCCCCEECHHHHHHH	8.27	28490779
185	Phosphorylation	YVSPALRYSQQAGSG EECHHHHHHHHCCCC	16.22	21082442
186	Phosphorylation	VSPALRYSQQAGSGL ECHHHHHHHHCCCCC	14.91	19429919
191	Phosphorylation	RYSQQAGSGLGGGPT HHHHHCCCCCCCCCC	33.58	21082442
198	Phosphorylation	SGLGGGPTGGALRPR CCCCCCCCCCCCCCC	52.07	22817900
212	Phosphorylation	RRAAPDITNTEFFPT CCCCCCCCCCCCCCH	43.39	21082442
252	Phosphorylation	RFQRVQESTAAPVAA HHHHHHHHCCCCHHH	13.27	21082442
253	Phosphorylation	FQRVQESTAAPVAAS HHHHHHHCCCCHHHH	26.53	22817900
265	Phosphorylation	AASNRFQSLDDEAS- HHHHHCCCCCCCCC-	30.93	19429919
271	Phosphorylation	QSLDDEAS------- CCCCCCCC-------	38.41	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CDV3_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CDV3_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CDV3_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EI3D2_DROME	CG4810	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-134, AND MASSSPECTROMETRY.
PubMed: 18327897