dbPTM

CDSN_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CDSN_MOUSE
UniProt AC	Q7TPC1
Protein Name	Corneodesmosin
Gene Name	Cdsn
Organism	Mus musculus (Mouse).
Sequence Length	561
Subcellular Localization	Secreted. Found in corneodesmosomes, the intercellular structures that are involved in desquamation..
Protein Description	Important for the epidermal barrier integrity..
Protein Sequence	MGSSRAPRMGSVGGHGLMALLMAGLILPGILAKSIGTLSDPCKDPTRITSPNDPCLIGKTGSNSISSQGGSSSFSSQGGSSSFSSHGGSSSSQGSSSGSLIYKPGTGYSQSSYSYGSGGSRPGGSGSQSGSSGSQSGSSGSQSGSSGSQSGSSGSQSGSSGSQSGSSGSQSGSSGSQSGSSGSQSGRWVSSSSQWVSSSSQSGSSGSSRDRPGSGSALPTGDKTSGMSQSGGSSTSQSSSSNLRPCSSNVPDSPCSGGPVITHSGPYISGTHTVSGGQRPVVVVVEQHGSGGPGFQGMPCSNGGPAGKPCPPITSVQKPYGGYEVVGGSANSYLVPGMTYSGGKIYPVGYFTKDNPIRGSPGAPSFAAGPPVSEGKYFSSNPIIPSRGSSSSSGYPVGVAFQPVGSGGVQPCGTGSVSSKGPCSGTRIQITSSSSSTSYHPCSGGPSQGPCSSPGTGSISGGSSSLSSGKIVLQPCGSKSTSSGYPCLSVPSSPLNGGLNGSPQPVPSVGVKLCGLNSPGRVPCRSIRNILTQVKPLGPQLMDPKVSLPQGEPQGEPLEKS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
207	Phosphorylation	SQSGSSGSSRDRPGS CCCCCCCCCCCCCCC	24.93	-
208	Phosphorylation	QSGSSGSSRDRPGSG CCCCCCCCCCCCCCC	41.55	-
333	Phosphorylation	VGGSANSYLVPGMTY CCCCCCCEECCCEEE	16.13	28576409
373	Phosphorylation	FAAGPPVSEGKYFSS CCCCCCCCCCCCCCC	46.54	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CDSN_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CDSN_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CDSN_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CDSN_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CDSN_MOUSE

Related Literatures of Post-Translational Modification