CDPKN_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CDPKN_ARATH
• UniProt AC: Q9M101
• Protein Name: Calcium-dependent protein kinase 23
• Gene Name: CPK23
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 520
• Subcellular Localization: Membrane ; Lipid-anchor .
• Protein Description: May play a role in signal transduction pathways that involve calcium as a second messenger. Could act as a calcium sensor involved in drought- and salt stress-induced calcium signaling cascades. Mediates the phosphorylation and activation of the S-type anion efflux channel SLAC1..
• Protein Sequence: MGCFSSKHRKTQNDGGGERSIPIIPVQTHIVDQVPDHRKPQIPSPSIPISVRDPETILGKPFEDIRKFYSLGRELGRGGLGITYMCKEIGTGNIYACKSILKRKLISELGREDVKTEIQIMQHLSGQPNVVEIKGSYEDRHSVHLVMELCAGGELFDRIIAQGHYSERAAAGTIKSIVDVVQICHLNGVIHRDLKPENFLFSSKEENAMLKVTDFGLSAFIEEGKIYKDVVGSPYYVAPEVLRQSYGKEIDIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSISDSAKDLVEKMLTEDPKRRITAAQVLEHPWIKGGEAPEKPIDSTVLSRMKQFRAMNKLKKLALKVSAVSLSEEEIKGLKTLFANMDTNRSGTITYEQLQTGLSRLRSRLSETEVQQLVEASDVDGNGTIDYYEFISATMHRYKLHHDEHVHKAFQHLDKDKNGHITRDELESAMKEYGMGDEASIKEVISEVDTDNDGKINFEEFRAMMRCGTTQPKGKQYPFH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGCFSSKHR ------CCCCCCCCC	22.60	-
44	Phosphorylation	HRKPQIPSPSIPISV CCCCCCCCCCCCCCC	32.67	30291188
69	Phosphorylation	FEDIRKFYSLGRELG HHHHHHHHHHCHHHC	13.16	23660473
70	Phosphorylation	EDIRKFYSLGRELGR HHHHHHHHHCHHHCC	27.72	23660473
233	Phosphorylation	IYKDVVGSPYYVAPE CCCCCCCCCEECCHH	9.71	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CDPKN_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CDPKN_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CDPKN_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
P2C56_ARATH	ABI1	physical	20385816
SLAC1_ARATH	OZS1	physical	20385816

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.