CDON_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CDON_RAT
• UniProt AC: O35158
• Protein Name: Cell adhesion molecule-related/down-regulated by oncogenes
• Gene Name: Cdon
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 1256
• Subcellular Localization: Cell membrane ; Single-pass membrane protein .
• Protein Description: Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity)..
• Protein Sequence: MHPDLGPLWKLLYVLVILCSSVSSDLATYFISEPLSAVQKLGRPVVLHCSAKPVTARISWLHNGKRLDRNTEQIKIHRGTLTILSLNPSLSGCYQCVANNSVGAVVSGPATVSADALADFDSSTMHVITAEKKNTGFIGCRVPESNPKAEVRYKIRGKWLMYSTGNYIILPSGNLQILNVSSKDKGSYKCAAYNPVTSELKVEPAGRKLLVSRPSSDGFHILHPALSQALAVLPHSPVTLECVVSGVPASQVYWLKDGQDCLSGSNWRRLYSHLATASIDPADSGNYSCVVGNNSSGDVKHVTYTVNVLEHASISKGLHDQKVSLGATVRFTCEVHGNPAPNRTWFHNAQPIRPSSRHLTEGSVLKITGVIMEDSGLYQCMADNGIGFMQSTGRLQIEQDSGQRPVIVTAPANVEVTDGDFVTLSCNATGEPVPVIHWYGRHGLITSHPSQVLRSKSRKSHLFRPGDLDPEPVYLIMSQAGSSSLSIQAVTREHAGKYTCEAVNKHGSTQSEAFLTVVPFETNTKAEPVTPSEASQNDERDPRDGSESGLLNLFPVKVHSGGVELPAEKNASVPDAPNILSPPQTHMPDTYTLVWRTGRDGGMPINAYFVKYRKLDDGSGAVGSWHTVRVPGSESELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNTQASFPPVGIPKRPVTSEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTWIPRANGGSPITAFKVEYKRMKSSDWLVAAEDIPPSKLSVEVRSLEPGSIYKFRVIVINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYIPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASEYPMKELSTPPSSSGNGGNVGPATSPARSSDMLYLIVGCVLGVMVLILLVFIALCLWKSRQQSAIQKYDPPGYLYQGSEINGQMVEYTTLSGTARINGSVHGGFLSKGSLSNGCSHLHHKGPNGVNGILNGTINGGLYSAHTSSLTRTCVEFEHPHHLVNGGAVYTAVPQMDPLECINCRNCRNNNRCFTKTNSPLPVVPVVASYPQDGLEMKPLGVMKFPVCPVSTVPDGGQIPEECLKDSVAPAPTQRTCRQDNTSDINSDSTEDTAEFNRGDSSGHSEAEDKVFSWSPLILSPVLEDCSEKTAWSPPGPPLDGLSVVLQQAQET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
99	N-linked_Glycosylation	GCYQCVANNSVGAVV CCEEHHHCCCCEEEE	22.40	-
179	N-linked_Glycosylation	SGNLQILNVSSKDKG CCCEEEEECCCCCCC	33.00	-
286	N-linked_Glycosylation	IDPADSGNYSCVVGN CCHHHCCCCEEEECC	29.51	-
293	N-linked_Glycosylation	NYSCVVGNNSSGDVK CCEEEECCCCCCCEE	33.33	-
294	N-linked_Glycosylation	YSCVVGNNSSGDVKH CEEEECCCCCCCEEE	31.46	-
342	N-linked_Glycosylation	VHGNPAPNRTWFHNA ECCCCCCCCCCEECC	57.00	-
427	N-linked_Glycosylation	DFVTLSCNATGEPVP CEEEEEECCCCCEEC	36.84	-
570	N-linked_Glycosylation	VELPAEKNASVPDAP EECCCCCCCCCCCCC	29.02	-
870	N-linked_Glycosylation	YRPTDSDNDSDYKRD ECCCCCCCCCCCCCH	55.42	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CDON_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CDON_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CDON_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ABL1_HUMAN	ABL1	physical	19470755
JIP4_HUMAN	SPAG9	physical	19470755

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.