CDON_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CDON_MOUSE
• UniProt AC: Q32MD9
• Protein Name: Cell adhesion molecule-related/down-regulated by oncogenes
• Gene Name: Cdon
• Organism: Mus musculus (Mouse).
• Sequence Length: 1250
• Subcellular Localization: Cell membrane; Single-pass membrane protein.
• Protein Description: Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells. Required for response to NTN3 and activation of NFATC3..
• Protein Sequence: MHPDLGPLWTLLYVLVILCSSVSSDLAPYFISEPLSAVQKLGRPVVLHCSAKPVTARISWLHNGKRLDRNTEQIKIHRGTLTILSLNPSLSGCYQCVANNSVGAVVSGPATVSAAALGDFDSSTMHVITAEEKNTGFIGCRVPESNPKAEVRYKIRGKWLKHSTGNYIILPSGNLQVLNVSSKDKGSYKCAAYNPVTSELKVEPTGRKLLVSRPSSNGFHILHPALSQALAVLPHSPVTLECVVSGVPASQVYWLKDGQDAVAGSNWRRLYSHLATASIDPADSGNYSCVVGNKSGDVKHVTYMVNVLEHASISKGLHDQKVSLGATVHFTCDVHGNPAPNRTWFHNAQPIHPSSRHLTEGNVLKITRVVMEDSGLYQCVADNGIGFMQSTGRLQIEQDSGWKPVIVTAPANIEVMDGDFVTLSCNATGVPVPVIHWYGRHGLITSHPSQVLRSKPRKSHLFRPGDLDLEPVYLIMSQAGSSSLSIQAVTLEHAGKYTCEATNKHGSTQSEAFLTVVPFETNTKAESVTPSEASQNDERDPQDGSESSLLNLFPVKVHPSGVELPAERNASVPDAPNILSPPQTHMPDTYNLVWRAGRDGGMPINAYFVKYRKLDDGSGAVGSWHTVRVPGSENELHLTELEPSSLYEVLMVARSAVGEGQPAMLTFRTSKEKMASSKNTQASFPPVGVPKRPVTAEASNSNFGVVLTDSSRHSGVPEAPDRPTISMASETSVYVTWIPRANGGSPITAFKVEYKRMRTSDWLVAAEDIPPSKLSVEVRSLEPGSIYKFRVIAINHYGESFRSSASRPYQVAGFPNRFSNRPITGPHIAYTEAVSDTQIMLKWTYVPSSNNNTPIQGFYIYYRPTDSDNDSDYKRDVVEGSKQWHTIGHLQPETSYDIKMQCFNEGGESEFSNVMICETKVKRVPGASDYPVKELSTPPSSSGNAGNVGPATSPARSSDMLYLIVGCVLGVMVLILMVFIALCLWKSRQQSTIQKYDPPGYLYQGSEINGQMVEYTTLSGAARINGSVHGGFLSNGCSHLHHKGPSGVNGTLSGNINGGLYSAHTNSLTRACVEFEHPHHLVNSGGVYTAVPQMDPLECINCRNCRNNNRCFTKTNSPLPVVPVVASYPQGGLEMKPLNAMKVPVCPASTVPDHGQLPDDCVKDSVAPIPTQHTCCQDNISDINSDSTEDTAEFSRGDSSGHSEAEDKVFSWNPLILSPVLEDCGEKTARSPPGPPLDGLSVVLQQAQET

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
99	N-linked_Glycosylation	GCYQCVANNSVGAVV CCEEHHHCCCCCEEE	22.40	-
179	N-linked_Glycosylation	SGNLQVLNVSSKDKG CCCEEEEECCCCCCC	32.54	-
286	N-linked_Glycosylation	IDPADSGNYSCVVGN CCHHHCCCCEEEECC	29.51	-
293	N-linked_Glycosylation	NYSCVVGNKSGDVKH CCEEEECCCCCCCEE	24.58	-
341	N-linked_Glycosylation	VHGNPAPNRTWFHNA CCCCCCCCCCCEECC	57.00	-
426	N-linked_Glycosylation	DFVTLSCNATGVPVP CEEEEEECCCCCCCE	36.84	-
455	Acetylation	PSQVLRSKPRKSHLF HHHHHHCCCCCCCCC	42.27	11999023
458	Acetylation	VLRSKPRKSHLFRPG HHHCCCCCCCCCCCC	51.24	11999019
569	N-linked_Glycosylation	VELPAERNASVPDAP CCCCCCCCCCCCCCC	28.24	-
869	N-linked_Glycosylation	YRPTDSDNDSDYKRD ECCCCCCCCCCCCCH	55.42	-
1088	Phosphorylation	LVNSGGVYTAVPQMD EECCCCCEEECCCCC	7.70	29514104
1117	Phosphorylation	RCFTKTNSPLPVVPV CEECCCCCCCCCEEE	32.80	25338131
1181	Phosphorylation	TCCQDNISDINSDST CCCCCCCHHCCCCCC	38.40	26370283
1185	Phosphorylation	DNISDINSDSTEDTA CCCHHCCCCCCCCCC	33.02	25338131
1228	Phosphorylation	LEDCGEKTARSPPGP HHHCCCCCCCCCCCC	24.01	25338131
1231	Phosphorylation	CGEKTARSPPGPPLD CCCCCCCCCCCCCCC	32.74	25338131
1241	Phosphorylation	GPPLDGLSVVLQQAQ CCCCCHHHHHHHHHH	18.73	29514104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CDON_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CDON_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CDON_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.