CDKG1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CDKG1_ARATH
• UniProt AC: Q9FGW5
• Protein Name: Cyclin-dependent kinase G1
• Gene Name: CDKG1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 612
• Subcellular Localization: Nucleus speckle .
• Protein Description: Cyclin-dependent kinase involved in pre-mRNA splicing. Required for the correct splicing of the sixth intron of CALS5 pre-mRNA. May stabilize the binding of U1 snRNP to this rare type of intron with a GC 5'SS. Involved in chromosome pairing and is required for the completion of synapsis in male meiocytes at high ambient temperatures..
• Protein Sequence: MAAGGVDVSRSSVAVKKDYDFYRNGSRDVYVRQSGRDDERRQIKRPSDHDLRRNDGRHRSRLAYEKGELREEAEVQRPSEKRRKFSPIVWNAEKVGRAPSREKTKSPFPVPTTTVISNQAVAGKTTSNDQVNALMSPEPSYLAPVQPSEALLAVKHPVDDLEEGQLEEEQVMQEDVKEGLLEEEQVMQEPNIKTSRWGTGLTSPKEELISVNVSKTNRWNRSSLTPECEEVMVSEEQQCYSSGSGSGHLSVEKLSADGNSGREYYSSDHDELEHEDQDSLTPGEMNMMFGSRSVNEFQKLNKINEGTYGIVYKARDEKTKEIVALKKIKMKEDRFEEEYGFPLTSLREINILLSCNHPAIVNVKEVVVGGKNDNDVYMVMEHLEHDLRGVMDRRKEPFSTSEVKCLMMQLLDGLKYLHTNWIIHRDLKPSNLLMNNCGELKICDFGMARQYGSPIKPYTQMVITQWYRPPELLLGAKEYSTAVDMWSVGCIMAELLSQKPLFPGKSELDQLQKIFAVLGTPNEAIWPGFSSFPNAKAKFPTQPYNMLRKKFPAISFVGGQILSERGFDLLNSLLTLDPEKRLTVEDALNHGWFHEVPLPKSKDFMPTYPPKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
86	Phosphorylation	SEKRRKFSPIVWNAE HHHHHCCCCCCCCHH		25561503
308	Phosphorylation	NKINEGTYGIVYKAR HCCCCCCCEEEEEEC		-
453	Phosphorylation	GMARQYGSPIKPYTQ HHHHHHCCCCCCCCE		-
459	Phosphorylation	GSPIKPYTQMVITQW CCCCCCCCEEEEEEE		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CDKG1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CDKG1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CDKG1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCL11_ARATH	RCY1	physical	20706207

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.