dbPTM

CDIP1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CDIP1_HUMAN
UniProt AC	Q9H305
Protein Name	Cell death-inducing p53-target protein 1
Gene Name	CDIP1
Organism	Homo sapiens (Human).
Sequence Length	208
Subcellular Localization	Late endosome membrane Peripheral membrane protein Cytoplasmic side . Lysosome membrane Peripheral membrane protein Cytoplasmic side .
Protein Description	Acts as an important p53/TP53-apoptotic effector. Regulates TNF-alpha-mediated apoptosis in a p53/TP53-dependent manner..
Protein Sequence	MSSEPPPPYPGGPTAPLLEEKSGAPPTPGRSSPAVMQPPPGMPLPPADIGPPPYEPPGHPMPQPGFIPPHMSADGTYMPPGFYPPPGPHPPMGYYPPGPYTPGPYPGPGGHTATVLVPSGAATTVTVLQGEIFEGAPVQTVCPHCQQAITTKISYEIGLMNFVLGFFCCFMGCDLGCCLIPCLINDFKDVTHTCPSCKAYIYTYKRLC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
21	Ubiquitination	TAPLLEEKSGAPPTP CCCCCCCCCCCCCCC	23000965
27	Phosphorylation	EKSGAPPTPGRSSPA CCCCCCCCCCCCCCC	23312004
119	Ubiquitination	TATVLVPSGAATTVT EEEEEEECCCCCEEE	23000965
119	Ubiquitination	TATVLVPSGAATTVT EEEEEEECCCCCEEE	21890473
126	Ubiquitination	SGAATTVTVLQGEIF CCCCCEEEEEECEEC	23000965
126	Ubiquitination	SGAATTVTVLQGEIF CCCCCEEEEEECEEC	21890473
159	Ubiquitination	KISYEIGLMNFVLGF HHHHHHHHHHHHHHH	23000965
159	Ubiquitination	KISYEIGLMNFVLGF HHHHHHHHHHHHHHH	21890473
166	Ubiquitination	LMNFVLGFFCCFMGC HHHHHHHHHHHHHCC	23000965
166	Ubiquitination	LMNFVLGFFCCFMGC HHHHHHHHHHHHHCC	21890473
198	Ubiquitination	THTCPSCKAYIYTYK CCCCHHHCEEEEEEH	23000965
204	Phosphorylation	CKAYIYTYKRLC--- HCEEEEEEHHCC---	29496907
205	Ubiquitination	KAYIYTYKRLC---- CEEEEEEHHCC----	23000965

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CDIP1_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CDIP1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CDIP1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CDIP1_HUMAN !!

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CDIP1_HUMAN

Related Literatures of Post-Translational Modification