| UniProt ID | CDF1_CAEEL | |
|---|---|---|
| UniProt AC | Q95QW4 | |
| Protein Name | Cation diffusion facilitator family protein 1 | |
| Gene Name | cdf-1 | |
| Organism | Caenorhabditis elegans. | |
| Sequence Length | 561 | |
| Subcellular Localization |
Cell membrane Multi-pass membrane protein . |
|
| Protein Description | Involved in the regulation of Pn.p cell fate determination. Involved in zinc metabolism and the decrease of the cytosolic zinc concentration which is thought to modulate Ras signaling.. | |
| Protein Sequence | MEVTMEDRSVKADKADRDDNNTTSTELLGKMRQTKVISTNQNNNHLIDRMVSIYEMEMIKSQSTETISDVSDVLEFTVIDNCSHGTHTLEHDLRLKGEPIGKSESVKGVSRSLIIQIGMTVIFCALEFITGVVCSSIAMLADSYHMAADVMALIVAFTCIKIATRPSTRLGYGWVRAETLGGFFNGIFMCTVCVLVFQEAVGRIINVHMITHPLQVLVIGFIGLLINLFGMFNLSGHGHSHGGGSHGHSHGGSHGHSHNNKKTKKNDGHGHSHANGHGHSHDGKSDCNGEEEPDHTRLNGKFRSASAMANSDANVRLLDNDDNSNDIIERRLSGVNSQNTIIATVDRQMTPYGTHMASEVLNVSSNNLDKSAQKTEQKKDKNVNIHGVWLHLLSDAFGSVIVMISAGFVYFLPTWKIAAYLDPILSISLASIMGFTAVVLVKTSGEKLLKQTPEGLDLEKVKKDLCSIVGVSKVEKLSVWTLCGQRIIAAAHVNICHPAVFPEAAYKIKNYFHDLGVHSTTIEPTFEDTCMQSMRIMVKKVVDGKSIEEPVSVSTENEITE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 311 | Phosphorylation | SASAMANSDANVRLL CHHHHCCCCCCEEEC | 28.67 | 30078680 | |
| 324 | Phosphorylation | LLDNDDNSNDIIERR ECCCCCCCCHHHHHH | 42.76 | 28854356 | |
| 333 | Phosphorylation | DIIERRLSGVNSQNT HHHHHHHCCCCCCCC | 38.59 | 28854356 | |
| 337 | Phosphorylation | RRLSGVNSQNTIIAT HHHCCCCCCCCEEEE | 23.54 | 30078680 | |
| 340 | Phosphorylation | SGVNSQNTIIATVDR CCCCCCCCEEEEECC | 13.21 | 30078680 | |
| 350 | Phosphorylation | ATVDRQMTPYGTHMA EEECCCCCCCCCCHH | 12.67 | 19530675 | |
| 352 | Phosphorylation | VDRQMTPYGTHMASE ECCCCCCCCCCHHHH | 26.03 | 19530675 | |
| 358 | Phosphorylation | PYGTHMASEVLNVSS CCCCCHHHHHHCCCC | 22.21 | 19530675 | |
| 364 | Phosphorylation | ASEVLNVSSNNLDKS HHHHHCCCCCCCCHH | 26.69 | 28854356 | |
| 365 | Phosphorylation | SEVLNVSSNNLDKSA HHHHCCCCCCCCHHH | 26.00 | 19530675 | |
| 552 | Phosphorylation | KSIEEPVSVSTENEI CCCCCCCCCCCCCCC | 22.52 | 30078680 | |
| 560 | Phosphorylation | VSTENEITE------ CCCCCCCCC------ | 29.48 | 30078680 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CDF1_CAEEL !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CDF1_CAEEL !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CDF1_CAEEL !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CDF1_CAEEL !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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