CDC5L_ARATH - dbPTM
CDC5L_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CDC5L_ARATH
UniProt AC P92948
Protein Name Cell division cycle 5-like protein
Gene Name CDC5
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 844
Subcellular Localization Nucleus .
Protein Description Component of the MAC complex that probably regulates defense responses through transcriptional control and thereby is essential for plant innate immunity. Possesses a sequence specific DNA sequence 'CTCAGCG' binding activity. Involved in mRNA splicing and cell cycle control. May also play a role in the response to DNA damage..
Protein Sequence MRIMIKGGVWKNTEDEILKAAVMKYGKNQWARISSLLVRKSAKQCKARWYEWLDPSIKKTEWTREEDEKLLHLAKLLPTQWRTIAPIVGRTPSQCLERYEKLLDAACTKDENYDAADDPRKLRPGEIDPNPEAKPARPDPVDMDEDEKEMLSEARARLANTRGKKAKRKAREKQLEEARRLASLQKRRELKAAGIDGRHRKRKRKGIDYNAEIPFEKRAPAGFYDTADEDRPADQVKFPTTIEELEGKRRADVEAHLRKQDVARNKIAQRQDAPAAILQANKLNDPEVVRKRSKLMLPPPQISDHELEEIAKMGYASDLLAENEELTEGSAATRALLANYSQTPRQGMTPMRTPQRTPAGKGDAIMMEAENLARLRDSQTPLLGGENPELHPSDFTGVTPRKKEIQTPNPMLTPSMTPGGAGLTPRIGLTPSRDGSSFSMTPKGTPFRDELHINEDMDMHESAKLERQRREEARRSLRSGLTGLPQPKNEYQIVAQPPPEESEEPEEKIEEDMSDRIAREKAEEEARQQALLKKRSKVLQRDLPRPPAASLAVIRNSLLSADGDKSSVVPPTPIEVADKMVREELLQLLEHDNAKYPLDDKAEKKKGAKNRTNRSASQVLAIDDFDENELQEADKMIKEEGKFLCVSMGHENKTLDDFVEAHNTCVNDLMYFPTRSAYELSSVAGNADKVAAFQEEMENVRKKMEEDEKKAEHMKAKYKTYTKGHERRAETVWTQIEATLKQAEIGGTEVECFKALKRQEEMAASFRKKNLQEEVIKQKETESKLQTRYGNMLAMVEKAEEIMVGFRAQALKKQEDVEDSHKLKEAKLATGEEEDIAIAMEASA
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
224PhosphorylationKRAPAGFYDTADEDR
CCCCCCCCCCCCCCC		16.0925561503
226PhosphorylationAPAGFYDTADEDRPA
CCCCCCCCCCCCCCH		25.3223111157
340PhosphorylationTRALLANYSQTPRQG
HHHHHHHCCCCCCCC		9.1319376835
341PhosphorylationRALLANYSQTPRQGM
HHHHHHCCCCCCCCC		27.6419376835
343PhosphorylationLLANYSQTPRQGMTP
HHHHCCCCCCCCCCC		17.9419376835
349PhosphorylationQTPRQGMTPMRTPQR
CCCCCCCCCCCCCCC		22.2830407730
353PhosphorylationQGMTPMRTPQRTPAG
CCCCCCCCCCCCCCC		19.9530407730
357PhosphorylationPMRTPQRTPAGKGDA
CCCCCCCCCCCCCCC		16.5525561503
378PhosphorylationNLARLRDSQTPLLGG
HHHHHHHCCCCCCCC		29.5323172892
380PhosphorylationARLRDSQTPLLGGEN
HHHHHCCCCCCCCCC		21.6123172892
393PhosphorylationENPELHPSDFTGVTP
CCCCCCHHHCCCCCC		34.3130407730
396PhosphorylationELHPSDFTGVTPRKK
CCCHHHCCCCCCCCC		35.4123172892
399PhosphorylationPSDFTGVTPRKKEIQ
HHHCCCCCCCCCCCC		20.7923172892
407PhosphorylationPRKKEIQTPNPMLTP
CCCCCCCCCCCCCCC		30.6030407730
413PhosphorylationQTPNPMLTPSMTPGG
CCCCCCCCCCCCCCC		13.6819880383
415PhosphorylationPNPMLTPSMTPGGAG
CCCCCCCCCCCCCCC		30.0125561503
417PhosphorylationPMLTPSMTPGGAGLT
CCCCCCCCCCCCCCC		24.1030407730
424PhosphorylationTPGGAGLTPRIGLTP
CCCCCCCCCCCCCCC		15.0319880383
430PhosphorylationLTPRIGLTPSRDGSS
CCCCCCCCCCCCCCC		17.6323776212
432PhosphorylationPRIGLTPSRDGSSFS
CCCCCCCCCCCCCCC		37.4623776212
436PhosphorylationLTPSRDGSSFSMTPK
CCCCCCCCCCCCCCC		32.2823776212
437PhosphorylationTPSRDGSSFSMTPKG
CCCCCCCCCCCCCCC		27.2023776212
439PhosphorylationSRDGSSFSMTPKGTP
CCCCCCCCCCCCCCC		24.5623776212
441PhosphorylationDGSSFSMTPKGTPFR
CCCCCCCCCCCCCCC		22.2023776212
615PhosphorylationAKNRTNRSASQVLAI
CCCCCCCCHHHEEEE		34.0530407730
617PhosphorylationNRTNRSASQVLAIDD
CCCCCCHHHEEEECC		23.2830407730
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CDC5L_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CDC5L_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CDC5L_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CDC5L_ARATH !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CDC5L_ARATH

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks.";
Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.;
Plant Physiol. 150:889-903(2009).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-343, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory