dbPTM

CDB4_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CDB4_SCHPO
UniProt AC	Q09184
Protein Name	Curved DNA-binding protein
Gene Name	cdb4
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	381
Subcellular Localization	Nucleus.
Protein Description	A non-essential protein that preferentially binds curved DNA. Binds non-curved DNA with a much lower affinity..
Protein Sequence	MSTKEATSETAVDYSLSNPETVNKYKIAGEVSQNVIKKVVELCQPGAKIYDICVRGDELLNEAIKKVYRTKDAYKGIAFPTAVSPNDMAAHLSPLKSDPEANLALKSGDVVKILLGAHIDGFASLVATTTVVSEEPVTGPAADVIAAASAALKAAQRTIKPGNTNWQVTDIVDKIATSYGCKPVAGMLSHQQEREVIDGKKQVILNPSDSQRSEMDTFTFEEGEVYGVDILVSTSPSGKVKRSDIATRIYKKTDTTYMLKLQASRKVYSEIQTKFGPFPFSTRNISFDSRTNMGLNECTSHKLLFPYEVLLDKDGGIVAEFYSTIALTKKGTIILSDSEPKEDFIKSDKKVEDPEIVALLETPIKVTKNKKKSKKPSKANE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
7	Phosphorylation	-MSTKEATSETAVDY -CCCCCCCCCCCCCC	28.34	29996109
8	Phosphorylation	MSTKEATSETAVDYS CCCCCCCCCCCCCCC	39.74	28889911
10	Phosphorylation	TKEATSETAVDYSLS CCCCCCCCCCCCCCC	31.58	25720772
286	Phosphorylation	PFSTRNISFDSRTNM CCCCCCEEECCCCCC	26.92	28889911
347	Phosphorylation	PKEDFIKSDKKVEDP CHHHHCCCCCCCCCH	50.26	25720772
362	Phosphorylation	EIVALLETPIKVTKN HHHHHEECCEECCCC	30.22	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CDB4_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CDB4_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CDB4_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CDB4_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CDB4_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-8 AND THR-362, AND MASSSPECTROMETRY.	18257517 [Abstract]