dbPTM

CD72_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CD72_MOUSE
UniProt AC	P21855
Protein Name	B-cell differentiation antigen CD72
Gene Name	Cd72
Organism	Mus musculus (Mouse).
Sequence Length	354
Subcellular Localization	Membrane Single-pass type II membrane protein.
Protein Description	Plays a role in B-cell proliferation and differentiation..
Protein Sequence	MADAITYADLRFVKVPLKNSASNHLGQDCEAYEDGELTYENVQVSPVPGGPPGLASPALADKAGVGSEQPTATWSSVNSSALRQIPRCPTVCLQYFLLGLLVSCLMLGVAVICLGVRYLQVSRQFQEGTRIWEATNSSLQQQLREKISQLGQKEVELQKARKELISSQDTLQEKQRTHEDAEQQLQACQAERAKTKENLKTEEERRRDLDQRLTSTRETLRRFFSDSSDTCCPCGWIPYQERCFYISHTLGSLEESQKYCTSLSSKLAAFDEPSKYYYEVSLPSGLEELLDRSKSYWIQMSKKWRQDSDSQSRHCVRIKTYYQKWERTISKCAELHPCICESEAFRFPDGINLN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MADAITYADLRFV --CCCCCCHHHCEEE	17.87	25367039
7	Phosphorylation	-MADAITYADLRFVK -CCCCCCHHHCEEEE	7.63	9590210
22	Phosphorylation	VPLKNSASNHLGQDC EECCCCCCCCCCCCC	25.30	24224561
38	Phosphorylation	AYEDGELTYENVQVS EECCCCEEEEEEEEE	25.20	-
39	Phosphorylation	YEDGELTYENVQVSP ECCCCEEEEEEEEEC	20.38	9590210
76	Phosphorylation	QPTATWSSVNSSALR CCCCCCHHCCHHHHH	25.73	-
136	N-linked_Glycosylation	TRIWEATNSSLQQQL CCHHHHCCHHHHHHH	36.33	-
166	Phosphorylation	KARKELISSQDTLQE HHHHHHHHCHHHHHH	34.27	30635358
167	Phosphorylation	ARKELISSQDTLQEK HHHHHHHCHHHHHHH	25.69	30635358
170	Phosphorylation	ELISSQDTLQEKQRT HHHHCHHHHHHHHHC	23.78	30635358
228	Phosphorylation	RRFFSDSSDTCCPCG HHHHCCCCCCCCCCC	41.07	-
230	Phosphorylation	FFSDSSDTCCPCGWI HHCCCCCCCCCCCCE	20.25	-
245	Phosphorylation	PYQERCFYISHTLGS EHHHHEEHHHHHCCC	12.73	25293948
247	Phosphorylation	QERCFYISHTLGSLE HHHEEHHHHHCCCHH	10.07	25293948
249	Phosphorylation	RCFYISHTLGSLEES HEEHHHHHCCCHHHH	19.64	25293948
252	Phosphorylation	YISHTLGSLEESQKY HHHHHCCCHHHHHHH	43.15	25293948

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
7	Y	Phosphorylation	Kinase	LYN	P25911	Uniprot
39	Y	Phosphorylation	Kinase	LYN	P25911	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CD72_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CD72_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CD72_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CD72_MOUSE

Related Literatures of Post-Translational Modification