CD48E_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CD48E_ARATH
• UniProt AC: Q9LZF6
• Protein Name: Cell division control protein 48 homolog E
• Gene Name: CDC48E
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 810
• Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton, phragmoplast. Primarily localized to the nucleus and, during cytokinesis, to the phragmoplast, a site where membrane vesicles are targeted in the deposition of new cell wall materials..
• Protein Description: Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity)..
• Protein Sequence: MSNEPESSDSKTKKDFSTAILERKKSPNRLVVDEAINDDNSVVSLHPTTMEKLQLFRGDTILIKGKKRKDTVCIALADETCEEPKIRMNKVVRSNLRVRLGDVISVHQCPDVKYGKRVHILPVDDTVEGVTGNLFDAYLKPYFLEAYRPVRKGDLFLVRGGMRSVEFKVIETDPAEYCVVAPDTEIFCEGEPVKREDEERLDEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTNGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLEVLRIHTKNMKLAEDVDLERISKDTHGYVGADLAALCTEAALQCIREKMDVIDLEDDSIDAEILNSMAVSNEHFHTALGNSNPSALRETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQRGNSAGDAGGAADRVLNQLLTEMDGMNAKKTVFIIGATNRPDIIDSALLRPGRLDQLIYIPLPDEDSRLNIFKACLRKSPVAKDVDVTALAKYTQGFSGADITEICQRACKYAIRENIEKDIENERRRSQNPEAMEEDMVDDEVSEIRAAHFEESMKYARRSVSDADIRKYQAFAQTLQQSRGFGSEFRFDSTAGVGRTTGVAAADPFATSAAAADDDDLYS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSNEPESSD ------CCCCCCCCC	50.31	-
8	Phosphorylation	MSNEPESSDSKTKKD CCCCCCCCCCCCHHH	44.21	23111157
10	Phosphorylation	NEPESSDSKTKKDFS CCCCCCCCCCHHHHH	44.14	23111157
17	Phosphorylation	SKTKKDFSTAILERK CCCHHHHHHHHHHCC	27.36	19880383
18	Phosphorylation	KTKKDFSTAILERKK CCHHHHHHHHHHCCC	20.08	27288362
41	Phosphorylation	EAINDDNSVVSLHPT ECCCCCCCCEEECCC	30.78	-
512	Phosphorylation	KFEKFGMSPSKGVLF HHHHCCCCCCCCEEE	26.80	19880383
750	Phosphorylation	SMKYARRSVSDADIR HHHHHHHCCCHHHHH	22.03	25561503
752	Phosphorylation	KYARRSVSDADIRKY HHHHHCCCHHHHHHH	28.47	29654922
774	Phosphorylation	QQSRGFGSEFRFDST HHHCCCCCCEEEECC	31.16	29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CD48E_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CD48E_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CD48E_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of CD48E_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.