dbPTM

CD48D_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CD48D_ARATH
UniProt AC	Q9SCN8
Protein Name	Cell division control protein 48 homolog D
Gene Name	CDC48D
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	815
Subcellular Localization	Nucleus . Cytoplasm, cytoskeleton, phragmoplast. Primarily localized to the nucleus and, during cytokinesis, to the phragmoplast, a site where membrane vesicles are targeted in the deposition of new cell wall materials..
Protein Description	Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity)..
Protein Sequence	MANQAESSDSKGTKKDFSTAILEKKKAANRLVVDEAINDDNSVVSLHPDTMEKLQLFRGDTILIKGKKRKDTVCIALADETCDEPKIRMNKVVRSNLRVRLGDVISVHQCPDVKYGNRVHILPLDDTIEGVSGNIFDAYLKPYFLEAYRPVRKGDLFLVRGGMRSIEFKVIETDPAEYCVVAPDTEIFCEGEPIKREDEERLDEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLEVLRIHTKNMKLAEDVDLERVSKDTHGYVGADLAALCTEAALQCIREKMDVIDLDDEEIDAEILNSMAVSNDHFQTALGNSNPSALRETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQRGNSVGDAGGAADRVLNQLLTEMDGMNAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRYQIFKSCLRKSPVAKDVDLRALAKYTQGFSGADITEICQRSCKYAIRENIEKDIEKERKRAESPEAMEEDEEEIAEIKAGHFEESMKYARRSVSDADIRKYQAFAQTLQQSRGFGSEFRFPDAPTGTTGAFPGAAATVGGVDPFATSGGAADDDDLYS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MANQAESSD ------CCCCCCCCC	19.49	22223895
8	Phosphorylation	MANQAESSDSKGTKK CCCCCCCCCCCCCCH	37.09	23111157
10	Phosphorylation	NQAESSDSKGTKKDF CCCCCCCCCCCCHHH	34.63	23111157
18	Phosphorylation	KGTKKDFSTAILEKK CCCCHHHHHHHHHHH	27.36	27288362
19	Phosphorylation	GTKKDFSTAILEKKK CCCHHHHHHHHHHHH	20.08	27288362
42	Phosphorylation	EAINDDNSVVSLHPD EHHCCCCCEEEECHH	30.78	-
513	Phosphorylation	KFEKFGMSPSKGVLF HHHHCCCCCCCCEEE	26.80	19880383
720	Phosphorylation	KERKRAESPEAMEED HHHHHCCCHHHHHHC	27.36	30291188
749	Phosphorylation	SMKYARRSVSDADIR HHHHHHHCCCHHHHH	22.03	25561503
751	Phosphorylation	KYARRSVSDADIRKY HHHHHCCCHHHHHHH	28.47	29654922
773	Phosphorylation	QQSRGFGSEFRFPDA HHHCCCCCCCCCCCC	31.16	29654922

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CD48D_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CD48D_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CD48D_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CD48D_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CD48D_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteomic analysis of nuclei-enriched fractions fromArabidopsis thaliana."; Jones A.M.E., MacLean D., Studholme D.J., Serna-Sanz A.,Andreasson E., Rathjen J.P., Peck S.C.; J. Proteomics 72:439-451(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-720, SUBCELLULARLOCATION, AND MASS SPECTROMETRY.	19245862 [Abstract]