CD2B2_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CD2B2_DROME
• UniProt AC: Q9VKV5
• Protein Name: CD2 antigen cytoplasmic tail-binding protein 2 homolog
• Gene Name: holn1
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 319
• Subcellular Localization: Nucleus .
• Protein Description: Required for embryonic epithelial tissue repair, but not for the assembly of the actomyosin cable at the wound edge. Probably acts downstream of rl in the regulation of Ddc and msn transcription to promote wound healing..
• Protein Sequence: MASKRKHQASQKVKEESFKKHTLDSDEEDSDDYEREYLNDSDIEGGEEGVAKVEDDVKVTPFNMKEELEEGHFDKDGHYHWNKETEAKDNWLDNIDWVKIGTQKNAFDPAKDEENSSDEEKNEPVGKAFNLSMNLMKMVEFMKPGETVKMTLQRLGKQRPVLTTLQRIKQKKAGIVDPKTQEISQLTELANEILSKTGNMDIYQDTYESIKAKIADLPGTSKPKVADDIDMYADDFETKELERSKTSSSDSSKPTTTTSEVTWEFKWSQDETDIQGPFSTEKMLKWSQENYFKNGVYVRKCGENTNFYTSNRIDFDLYL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Acetylation	HQASQKVKEESFKKH HHHHHHHHHHHHHHH		21791702
17	Phosphorylation	SQKVKEESFKKHTLD HHHHHHHHHHHHCCC		22817900
22	Phosphorylation	EESFKKHTLDSDEED HHHHHHHCCCCCCCC		20450229
25	Phosphorylation	FKKHTLDSDEEDSDD HHHHCCCCCCCCCCH		19429919
30	Phosphorylation	LDSDEEDSDDYEREY CCCCCCCCCHHHHHH		19429919
33	Phosphorylation	DEEDSDDYEREYLND CCCCCCHHHHHHHCH		22817900
37	Phosphorylation	SDDYEREYLNDSDIE CCHHHHHHHCHHCCC		19429919
41	Phosphorylation	EREYLNDSDIEGGEE HHHHHCHHCCCCCCC		19429919
116	Phosphorylation	PAKDEENSSDEEKNE CCCCCCCCCHHHHCC		19429919
117	Phosphorylation	AKDEENSSDEEKNEP CCCCCCCCHHHHCCC		19429919
163	Phosphorylation	GKQRPVLTTLQRIKQ HCCCCHHHHHHHHHH		19429919
164	Phosphorylation	KQRPVLTTLQRIKQK CCCCHHHHHHHHHHH		19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CD2B2_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CD2B2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CD2B2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.