CCSE1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCSE1_HUMAN
• UniProt AC: Q9C0I3
• Protein Name: Serine-rich coiled-coil domain-containing protein 1
• Gene Name: CCSER1
• Organism: Homo sapiens (Human).
• Sequence Length: 900
• Protein Sequence: MGDSGSRRSTLVSRLPIFRRSINRRHDSLPSSPSSSNTVGVHSSSPSSTNSSSGSTGKRRSIFRTPSISFHHKKGSEPKQEPTNQNLSISNGAQPGHSNMQKLSLEEHIKTRGRHSVGFSSSRNKKITRSLTEDFEREKEHSTNKNVFINCLSSGKSEGDDSGFTEDQTRRSVKQSTRKLLPKSFSSHYKFSKPVLQSQSISLVQQSEFSLEVTQYQEREPVLVRASPSCSVDVTERAGSSLQSPLLSADLTTAQTPSEFLALTEDSVSEMDAFSKSGSMASHCDNFGHNDSTSQMSLNSAAVTKTTTELTGTVPCAIMSPGKYRLEGQCSTESNSLPETSAANQKEVLLQIAELPATSVSHSESNLPADSEREENIGLQNGETMLGTNSPRKLGFYEQHKAIAEHVKGIHPISDSKIIPTSGDHHIFNKTSHGYEANPAKVLASSLSPFREGRFIERRLRSSSEGTAGSSRMILKPKDGNIEEVNSLRKQRAGSSSSKMNSLDVLNNLGSCELDEDDLMLDLEFLEEQSLHPSVCREDSYHSVVSCAAVVLTPMEPMIEMKKREEPEFPEPSKQNLSLKLTKDVDQEARCSHISRMPNSPSADWPLQGVEENGGIDSLPFRLMLQDCTAVKTLLLKMKRVLQESADMSPASSTTSLPVSPLTEEPVPFKDIMKDECSMLKLQLKEKDELISQLQEELGKVRHLQKAFASRVDKSTQTELLCYDGLNLKRLETVQGGREATYRNRIVSQNLSTRDRKAIHTPTEDRFRYSAADQTSPYKNKTCQLPSLCLSNFLKDKELAEVIKHSRGTYETLTSDVTQNLRATVGQSSLKPTAKTEGLSTFLEKPKDQVATARQHSTFTGRFGQPPRGPISLHMYSRKNVFLHHNLHSTELQTLGQQDG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	GDSGSRRSTLVSRLP CCCCCCCHHHHHHHH		30631047
10	Phosphorylation	DSGSRRSTLVSRLPI CCCCCCHHHHHHHHH		23911959
13	Phosphorylation	SRRSTLVSRLPIFRR CCCHHHHHHHHHHHH		29970186
35	Phosphorylation	SLPSSPSSSNTVGVH CCCCCCCCCCCCEEE		-
36	Phosphorylation	LPSSPSSSNTVGVHS CCCCCCCCCCCEEEC		30576142
43	Phosphorylation	SNTVGVHSSSPSSTN CCCCEEECCCCCCCC		30576142
44	Phosphorylation	NTVGVHSSSPSSTNS CCCEEECCCCCCCCC		30576142
49	Phosphorylation	HSSSPSSTNSSSGST ECCCCCCCCCCCCCC		30576142
51	Phosphorylation	SSPSSTNSSSGSTGK CCCCCCCCCCCCCCC		30576142
52	Phosphorylation	SPSSTNSSSGSTGKR CCCCCCCCCCCCCCC		30576142
53	Phosphorylation	PSSTNSSSGSTGKRR CCCCCCCCCCCCCCC		-
55	Phosphorylation	STNSSSGSTGKRRSI CCCCCCCCCCCCCCE		-
56	Phosphorylation	TNSSSGSTGKRRSIF CCCCCCCCCCCCCEE		30576142
65	Phosphorylation	KRRSIFRTPSISFHH CCCCEEECCCEEEEC		23312004
67	Phosphorylation	RSIFRTPSISFHHKK CCEEECCCEEEECCC		23312004
69	Phosphorylation	IFRTPSISFHHKKGS EEECCCEEEECCCCC		23312004
76	Phosphorylation	SFHHKKGSEPKQEPT EEECCCCCCCCCCCC		-
116	Phosphorylation	IKTRGRHSVGFSSSR HHHCCCCCCCCCCCC		28348404
128	Phosphorylation	SSRNKKITRSLTEDF CCCCCCCHHHHHHHH		-
130	Phosphorylation	RNKKITRSLTEDFER CCCCCHHHHHHHHHH		27273156
132	Phosphorylation	KKITRSLTEDFEREK CCCHHHHHHHHHHHH		21815630
142	Phosphorylation	FEREKEHSTNKNVFI HHHHHHHCCCCCEEE		26699800
143	Phosphorylation	EREKEHSTNKNVFIN HHHHHHCCCCCEEEE		26699800
153	Phosphorylation	NVFINCLSSGKSEGD CEEEEECCCCCCCCC		26699800
157	Phosphorylation	NCLSSGKSEGDDSGF EECCCCCCCCCCCCC		-
162	Phosphorylation	GKSEGDDSGFTEDQT CCCCCCCCCCCHHHH		-
165	Phosphorylation	EGDDSGFTEDQTRRS CCCCCCCCHHHHHHH		-
169	Phosphorylation	SGFTEDQTRRSVKQS CCCCHHHHHHHHHHH		-
189	Phosphorylation	PKSFSSHYKFSKPVL CCCHHHCCCCCCHHH		-
227	Phosphorylation	EPVLVRASPSCSVDV CCEEEEECCCCCCCC		28857561
320	Phosphorylation	TVPCAIMSPGKYRLE EEEEEEECCCEEEEE		28348404
331	Phosphorylation	YRLEGQCSTESNSLP EEEEEEECCCCCCCC		23898821
332	Phosphorylation	RLEGQCSTESNSLPE EEEEEECCCCCCCCC		28348404
334	Phosphorylation	EGQCSTESNSLPETS EEEECCCCCCCCCCC		28348404
336	Phosphorylation	QCSTESNSLPETSAA EECCCCCCCCCCCCC		28555341
397	Phosphorylation	SPRKLGFYEQHKAIA CCCCCCHHHHHHHHH		25159151
421	Phosphorylation	SDSKIIPTSGDHHIF CCCCEECCCCCCCCC		28555341
422	Phosphorylation	DSKIIPTSGDHHIFN CCCEECCCCCCCCCC		28555341
445	Phosphorylation	NPAKVLASSLSPFRE CHHHHHHHHCCCCCC		27732954
446	Phosphorylation	PAKVLASSLSPFREG HHHHHHHHCCCCCCC		22167270
448	Phosphorylation	KVLASSLSPFREGRF HHHHHHCCCCCCCHH		22167270
462	Phosphorylation	FIERRLRSSSEGTAG HHHHHHHCCCCCCCC		23532336
464	Phosphorylation	ERRLRSSSEGTAGSS HHHHHCCCCCCCCCC		27282143
471	Phosphorylation	SEGTAGSSRMILKPK CCCCCCCCCEEECCC		23532336
487	Phosphorylation	GNIEEVNSLRKQRAG CCHHHHHHHHHHHCC		25159151
495	O-linked_Glycosylation	LRKQRAGSSSSKMNS HHHHHCCCCCCHHHH		30379171
495	Phosphorylation	LRKQRAGSSSSKMNS HHHHHCCCCCCHHHH		33259812
540	Phosphorylation	PSVCREDSYHSVVSC HHHCCCCCCHHHHHE		27251275
541	Phosphorylation	SVCREDSYHSVVSCA HHCCCCCCHHHHHEE		27251275
543	Phosphorylation	CREDSYHSVVSCAAV CCCCCCHHHHHEEEE		27251275
578	Phosphorylation	EPSKQNLSLKLTKDV CCCCCCEEEEECCCC		24719451
600	Phosphorylation	HISRMPNSPSADWPL HHHCCCCCCCCCCCC		26657352
602	Phosphorylation	SRMPNSPSADWPLQG HCCCCCCCCCCCCCC		28450419
618	Phosphorylation	EENGGIDSLPFRLML HHCCCCCCCCHHHHH		-
649	Phosphorylation	LQESADMSPASSTTS HHHCCCCCCCCCCCC		23898821
652	Phosphorylation	SADMSPASSTTSLPV CCCCCCCCCCCCCCC		28348404
653	Phosphorylation	ADMSPASSTTSLPVS CCCCCCCCCCCCCCC		28348404
654	Phosphorylation	DMSPASSTTSLPVSP CCCCCCCCCCCCCCC		28348404
655	Phosphorylation	MSPASSTTSLPVSPL CCCCCCCCCCCCCCC		28348404
656	Phosphorylation	SPASSTTSLPVSPLT CCCCCCCCCCCCCCC		27251275
678	Phosphorylation	DIMKDECSMLKLQLK HHCHHHHHHHHHHHH		26074081
710	Phosphorylation	HLQKAFASRVDKSTQ HHHHHHHHCCCCCCC		-
741	Phosphorylation	VQGGREATYRNRIVS ECCCCHHHHHHHHHH		23403867
742	Phosphorylation	QGGREATYRNRIVSQ CCCCHHHHHHHHHHC		23403867
761	Phosphorylation	RDRKAIHTPTEDRFR CCCCCCCCCCCCCCC		27251275
775	Phosphorylation	RYSAADQTSPYKNKT CCCCCCCCCCCCCCC		27732954
776	Phosphorylation	YSAADQTSPYKNKTC CCCCCCCCCCCCCCC		27732954
778	Phosphorylation	AADQTSPYKNKTCQL CCCCCCCCCCCCCCC		27732954
787	Phosphorylation	NKTCQLPSLCLSNFL CCCCCCCHHHHHHHC		26074081
791	Phosphorylation	QLPSLCLSNFLKDKE CCCHHHHHHHCCCHH		26074081
845	Ubiquitination	GLSTFLEKPKDQVAT CHHHHHHCCHHHHHH		-
857	Phosphorylation	VATARQHSTFTGRFG HHHHHHCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCSE1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCSE1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCSE1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SMYD2_HUMAN	SMYD2	physical	28514442
NDE1_HUMAN	NDE1	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.