CCR4A_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCR4A_ARATH
• UniProt AC: Q8W0Z9
• Protein Name: Carbon catabolite repressor protein 4 homolog 1
• Gene Name: CCR4-1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 602
• Subcellular Localization: Nucleus. Cytoplasm.
• Protein Description: Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover..
• Protein Sequence: MLSVIRVHLPSEIPIVGCELTPYVLLRRPDKTPSTDDVPESAPLEGHFLKYRWFRVQSDKKVAICSVHPSETATLQCLGCLKSKVPVAKSYHCSTKCFSDAWQHHRVLHERAASAATEGNDEEELPRLNSSGSGSGVLSTSVSLTNGSSSVYPSAITQKTGAGGETLVEVGRSKTYTPMADDICHVLKFECVVVNAETKQNVGLSCTILTSRVIPAPSPSPRRLISISGTDVTGHLDSNGRPLSMGTFTVLSYNILSDTYASSDIYSYCPTWALAWTYRRQNLLREIVKYRADIVCLQEVQNDHFEEFFLPELDKHGYQGLFKRKTNEVFIGNTNTIDGCATFFRRDRFSHVKKYEVEFNKAAQSLTEAIIPVSQKKNALNRLVKDNVALIVVLEAKFGSQAADNPGKRQLLCVANTHVNVPHELKDVKLWQVHTLLKGLEKIAASADIPMLVCGDFNTVPASAPHTLLAVGKVDPLHPDLMVDPLGILRPHSKLTHQLPLVSAYSQFAKMGGNVITEQQRRRLDPASSEPLFTNCTRDFIGTLDYIFYTADTLTVESLLELLDEESLRKDTALPSPEWSSDHIALLAEFRCMPRARRNNIL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
133	Phosphorylation	PRLNSSGSGSGVLST CCCCCCCCCCCEEEE	31.56	25368622
135	Phosphorylation	LNSSGSGSGVLSTSV CCCCCCCCCEEEEEE	27.68	25368622
139	Phosphorylation	GSGSGVLSTSVSLTN CCCCCEEEEEEEECC	19.07	25368622
218	Phosphorylation	SRVIPAPSPSPRRLI CCEECCCCCCCCEEE	39.87	23328941
220	Phosphorylation	VIPAPSPSPRRLISI EECCCCCCCCEEEEE	35.06	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCR4A_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCR4A_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCR4A_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
Y4554_ARATH	AT4G15545	physical	21798944

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.