CCHCR_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCHCR_MOUSE
• UniProt AC: Q8K2I2
• Protein Name: Coiled-coil alpha-helical rod protein 1
• Gene Name: Cchcr1
• Organism: Mus musculus (Mouse).
• Sequence Length: 770
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: May be a regulator of keratinocyte proliferation or differentiation..
• Protein Sequence: MLPPSGFAGLVPPSHFQARPLPTLPRMAPTWASDVPLVQSPASQDVLERRLDAQRSTVTTWGQDFCGDGQGLGRRGRSLELGFSSALSQQAELISRQLQELRRLEEEVRSLRETSLQQKMRLETQAVELDALAVAEKAGQAEAEGLRTALAGAEMVRKNLEEAKHKELEEIQSLHQEQLSSLTQAHQKALDSLASKAEGLEKSLNSLETKRAGEAKQLAMAQKEADMLRNQLSKTQEELEAQVTLVESLRKYVGEQVLPEFPSQEWELERKELLDTLKHLKEDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPLDPLEPEFPKKCRSLLRNWREKVFALMVQLKAQDLQHRDSTSQLRIQVAELQEQVTSQSQEQAILQRALQDKTAQVEVERMSTKSLQMELDQAQEARRRQEQQIASAEEQLKFVVGAMNSTQAKLQSTMTRMDQAVARIPSLSNRLSYAVRKVHTIKGLMARKVALAQLRVESSPPSEAAPPLDTDLSVELEQLREERNRLDAELQLSAHLIQQEVGRAREQGEVERRRLIEVAQQLEQELQRAQESLASVGQQLEAARRGQQESTEEAASLRQELTQQQEIYGQALQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHKATQEKERNQELRRLQDEARKEEGQRLTRRVQELERDKNLMLQRLLAVLPSGVNKKCSPRSVESSSSESPAAASCKESVKGSLTVLLDNLQGLSEAISRDEDICVEDNQNTKKTKNPPSDPLLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
40	Phosphorylation	SDVPLVQSPASQDVL CCCCCCCCCCCHHHH	18.23	25338131
358	Phosphorylation	QDLQHRDSTSQLRIQ HHHCCCCCCHHHHHH	29.89	25367039
359	Phosphorylation	DLQHRDSTSQLRIQV HHCCCCCCHHHHHHH	25.44	25367039
360	Phosphorylation	LQHRDSTSQLRIQVA HCCCCCCHHHHHHHH	31.04	25367039
374	Phosphorylation	AELQEQVTSQSQEQA HHHHHHHCCHHHHHH	22.27	25367039
375	Phosphorylation	ELQEQVTSQSQEQAI HHHHHHCCHHHHHHH	29.04	25367039
377	Phosphorylation	QEQVTSQSQEQAILQ HHHHCCHHHHHHHHH	35.14	25367039
491	Phosphorylation	LAQLRVESSPPSEAA HHHHHCCCCCCCCCC	45.33	25293948
492	Phosphorylation	AQLRVESSPPSEAAP HHHHCCCCCCCCCCC	27.59	25293948
495	Phosphorylation	RVESSPPSEAAPPLD HCCCCCCCCCCCCCC	43.16	25293948
503	Phosphorylation	EAAPPLDTDLSVELE CCCCCCCCCHHHHHH	46.66	25293948
506	Phosphorylation	PPLDTDLSVELEQLR CCCCCCHHHHHHHHH	19.16	25293948
730	Phosphorylation	ESVKGSLTVLLDNLQ HHHHHHHHHHHHHHH	15.71	21454597
740	Phosphorylation	LDNLQGLSEAISRDE HHHHHHHHHHHHCCC	31.63	21454597

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCHCR_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCHCR_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCHCR_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CCHCR_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.