CCDC7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCDC7_HUMAN
• UniProt AC: Q96M83
• Protein Name: Coiled-coil domain-containing protein 7
• Gene Name: CCDC7
• Organism: Homo sapiens (Human).
• Sequence Length: 1385
• Protein Description: May play a role in tumorigenesis..
• Protein Sequence: MKPVKHLLTTSNKSANVPALTTKKGLHNLPLSPELKEKHNAKLIHDKIEPMVLRSPPTGESILRYALPIPSSKTKNLLPEDEMIGKIIKHLKMVVSTLEETYGHCDQNGEEPFVKHEHEELSLSVGDDMNSFLTYCSQFAAQLEEALKEEQNILESLFKWFQWQVNQMEEISKDQTLLQAEPPKPDKTVILNIAEIVRLVQRFEELKNRLKQRSKSSVKVMLSKTMDKENRPEAVKSCEALAQKIEEFLEAHSTDEFKDVSATEPQTAHSMTNRFNAMLKVFENQANMLERAVNDQVLLDAEYKQMQCDFQLLSEEKLVLENELQKLKDKEKTKPTNNRTKKAVKTVKKKDKGKSEDSEKKMSPEKEFKIKEDLDQVQKVARLEIENKVLQEQLKQALQEAEKAKHQLNYFLNQEKLLKSEGKTETTMQVGNSQTKVKGEDSKNIPLEKETRKSLVSDSGGQRTSDKIQEYPQITAQSGRLIEKSSEKKRSSPAISDLSQILKSQDESAFLESSNEVSVAENQSYKSPSETHDKSLTTVSSSKEVQDSLSVGTLAQKNETVISPFILPPVLTESKKADVSEEQLQKMTEEQTYQAAEKSQADSEVPDENLMVENKDSVTKVQIEQMKQRTSSMERHEETLTTPQLPEDMVLVSRIQSETKNLKATRNESFHSHNDVPEENLMLEQDTKSKTEVEVKKQKSFQDNQLSTHNEVPNERLVVEHQESLSKTKLQIKKQETSTEQPLTTPDKEPNENLILRHQDSMSKSEMQVKEQRTLKGQRIITHDEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVSKIQVQLEIQETSEGEGRSIPDKNSMFVHQDSVSKLQMQEKKKITPGRERRNTRIVVPNENVISVHQDSKSKLQMQEKKQINSGVERHKTFPLEIKKKDISLEHLLPEEKVLLSRSESQTKKLQAKVTSRKIKNEAASELPDTAENLPAMYPSISDLIIQFDLNKVVETDIESLRGALGRRLLNDEFKTQSKSFPGPDIEQLTDAFGRDILKDEFKTRSKSLPETDERLHSTTERGTINDAIKTQLKRKSYPETVLKHLKGVNGKDIIKHLINIQSKSHGETDKEHLADDTGRGIIKGSINAQLKGHQKTDKNFFAYATGRGLMKESTTTQLKSHPETDKEFLADAIGRGIIIGPITTQLKSHRETDKELLKDAIGRDIIKGPISAQLKSHQETDVEPLTNAIGSSKTIGEIKTQLRTHYDVNLFKNKDMSVQRQEGIFTRSITPSKFPTKVINLSPFENKEETYEYSSPYVTAPSKAIYRTYRAGPSFSKDIHLPLLNQLPSGHSKVVTLSQKTIEFTLPTVTNTVGKPTYKVLHAAARKSVPHPYF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MKPVKHLLT ------CCCCCEEEC	59.52	-
2	Phosphorylation	------MKPVKHLLT ------CCCCCEEEC	59.52	-
6	Phosphorylation	--MKPVKHLLTTSNK --CCCCCEEECCCCC	26.72	-
6	Phosphorylation	--MKPVKHLLTTSNK --CCCCCEEECCCCC	26.72	-
21	Phosphorylation	SANVPALTTKKGLHN CCCCCCCCCCCCHHC	38.38	24719451
32	Phosphorylation	GLHNLPLSPELKEKH CHHCCCCCHHHHHHH	17.87	24719451
38	2-Hydroxyisobutyrylation	LSPELKEKHNAKLIH CCHHHHHHHCCCCCC	40.34	-
55	Phosphorylation	IEPMVLRSPPTGESI CCCCEECCCCCCCHH	30.94	30622161
58	Phosphorylation	MVLRSPPTGESILRY CEECCCCCCCHHHHH	57.89	30622161
61	Phosphorylation	RSPPTGESILRYALP CCCCCCCHHHHHHCC	28.41	30622161
71	Phosphorylation	RYALPIPSSKTKNLL HHHCCCCCHHCCCCC	45.23	30622161
72	Phosphorylation	YALPIPSSKTKNLLP HHCCCCCHHCCCCCC	38.70	30622161
127	Phosphorylation	ELSLSVGDDMNSFLT EECEECCCCHHHHHH	50.24	-
127	Phosphorylation	ELSLSVGDDMNSFLT EECEECCCCHHHHHH	50.24	-
132	Phosphorylation	VGDDMNSFLTYCSQF CCCCHHHHHHHHHHH	5.12	23836654
132	Phosphorylation	VGDDMNSFLTYCSQF CCCCHHHHHHHHHHH	5.12	23836654
156	Phosphorylation	EEQNILESLFKWFQW HHHHHHHHHHHHHHH	35.34	24719451
237	Phosphorylation	NRPEAVKSCEALAQK CCHHHHHHHHHHHHH	15.59	30622161
314	Phosphorylation	QCDFQLLSEEKLVLE CCCHHHHCHHHHHHH	52.91	29978859
333	O-linked_Glycosylation	KLKDKEKTKPTNNRT HHHHHCCCCCCCHHH	43.26	30379171
333	Phosphorylation	KLKDKEKTKPTNNRT HHHHHCCCCCCCHHH	43.26	29083192
336	Phosphorylation	DKEKTKPTNNRTKKA HHCCCCCCCHHHHHH	46.83	29083192
342	Acetylation	PTNNRTKKAVKTVKK CCCHHHHHHHHHHHH	58.77	130537
345	Phosphorylation	NRTKKAVKTVKKKDK HHHHHHHHHHHHHCC	53.08	-
345	Phosphorylation	NRTKKAVKTVKKKDK HHHHHHHHHHHHHCC	53.08	-
345	Acetylation	NRTKKAVKTVKKKDK HHHHHHHHHHHHHCC	53.08	130533
348	Acetylation	KKAVKTVKKKDKGKS HHHHHHHHHHCCCCC	60.38	130535
352	Phosphorylation	KTVKKKDKGKSEDSE HHHHHHCCCCCCCHH	76.69	-
352	Phosphorylation	KTVKKKDKGKSEDSE HHHHHHCCCCCCCHH	76.69	-
355	Phosphorylation	KKKDKGKSEDSEKKM HHHCCCCCCCHHHCC	56.13	26074081
358	Phosphorylation	DKGKSEDSEKKMSPE CCCCCCCHHHCCCHH	47.46	26074081
359	Phosphorylation	KGKSEDSEKKMSPEK CCCCCCHHHCCCHHH	69.85	-
359	Phosphorylation	KGKSEDSEKKMSPEK CCCCCCHHHCCCHHH	69.85	-
363	Phosphorylation	EDSEKKMSPEKEFKI CCHHHCCCHHHHCCC	38.49	26074081
424	Phosphorylation	LLKSEGKTETTMQVG HHHCCCCCCEEEEEC	49.79	-
433	Phosphorylation	TTMQVGNSQTKVKGE EEEEECCCCEEECCC	33.04	-
435	Phosphorylation	MQVGNSQTKVKGEDS EEECCCCEEECCCCC	37.31	-
454	Phosphorylation	LEKETRKSLVSDSGG CCHHHHHHHCCCCCC	30.61	30622161
457	Phosphorylation	ETRKSLVSDSGGQRT HHHHHHCCCCCCCCC	31.21	30622161
499	Phosphorylation	SPAISDLSQILKSQD CCHHHHHHHHHHCCC		23403867
568	Phosphorylation	VISPFILPPVLTESK EEECCCCCCCCCCCC		-
568	Phosphorylation	VISPFILPPVLTESK EEECCCCCCCCCCCC		-
588	Phosphorylation	EEQLQKMTEEQTYQA HHHHHHHCHHHHHHH		-
592	Phosphorylation	QKMTEEQTYQAAEKS HHHCHHHHHHHHHHH		-
820	Phosphorylation	PREKRHSTHDEESGE CHHHCCCCCCCCCCC		-
825	Phosphorylation	HSTHDEESGENPMLK CCCCCCCCCCCCCCC		23836654
869	Phosphorylation	SMFVHQDSVSKLQMQ CCEECHHHHHHHHHH		26670566
890	Phosphorylation	PGRERRNTRIVVPNE CCCCCCCCEEECCCC		26657352
938	Phosphorylation	EIKKKDISLEHLLPE EEECCCCCHHHHCCH		25693802
1074	Phosphorylation	HSTTERGTINDAIKT HHHCCCCCHHHHHHH		-
1081	Phosphorylation	TINDAIKTQLKRKSY CHHHHHHHHHHHCCC		-
1088	Phosphorylation	TQLKRKSYPETVLKH HHHHHCCCHHHHHHH		-
1199	Phosphorylation	PITTQLKSHRETDKE CHHHHHHHCHHHCHH		24719451
1203	Phosphorylation	QLKSHRETDKELLKD HHHHCHHHCHHHHHH		24719451
1237	Phosphorylation	ETDVEPLTNAIGSSK CCCCHHHHHHHCCCC		22210691
1245	Phosphorylation	NAIGSSKTIGEIKTQ HHHCCCCCHHHHHHH		22210691
1251	Phosphorylation	KTIGEIKTQLRTHYD CCHHHHHHHHHHHCC		22210691
1325	Phosphorylation	RTYRAGPSFSKDIHL HHHCCCCCCCCCCCH		24719451
1327	Phosphorylation	YRAGPSFSKDIHLPL HCCCCCCCCCCCHHH		29449344
1352	Phosphorylation	VVTLSQKTIEFTLPT EEEEECCEEEEECCC		22210691
1359	Phosphorylation	TIEFTLPTVTNTVGK EEEEECCCCCCCCCC		22210691

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCDC7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCDC7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCDC7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CCDC7_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.