CCDC6_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCDC6_MOUSE
• UniProt AC: D3YZP9
• Protein Name: Coiled-coil domain-containing protein 6
• Gene Name: Ccdc6
• Organism: Mus musculus (Mouse).
• Sequence Length: 469
• Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. May be a cytoskeletal protein..
• Protein Sequence: MADSASESDTDAAGGGPAAMQSSCSATSGGSGGGGGGKSGGIVISPFRLEELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTLFKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMKKIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLDQPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERHMREENLRLQRKLQREMERREALCRQLSESESSLEMDDERYFNEMSAQGLRPRTVSSPIPYTPSPSSSRPISPGLSYASHTVGFTPPTSLTRAGMSYYNSPGLHVQHMGASHGITRPSPRRSSSPDKFKRPTPPPSPNTQSPVQPPPPPPPPPMQPAVPSAAPTQPAPTQPQHPVHPSSQP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MADSASESD ------CCCCCCCCC	21.33	-
4	Phosphorylation	----MADSASESDTD ----CCCCCCCCCCC	24.93	23684622
6	Phosphorylation	--MADSASESDTDAA --CCCCCCCCCCCCC	41.40	23684622
8	Phosphorylation	MADSASESDTDAAGG CCCCCCCCCCCCCCC	43.23	24224561
10	Phosphorylation	DSASESDTDAAGGGP CCCCCCCCCCCCCCC	36.50	22324799
25	Phosphorylation	AAMQSSCSATSGGSG CCCCCCCCCCCCCCC	36.21	23375375
39	Phosphorylation	GGGGGGKSGGIVISP CCCCCCCCCCEEECC	45.59	26643407
45	Phosphorylation	KSGGIVISPFRLEEL CCCCEEECCCCHHHH	13.69	26824392
53	Phosphorylation	PFRLEELTNRLASLQ CCCHHHHHHHHHHHH	22.90	24759943
74	Acetylation	KIELETYKLKCKALQ EEEHHHHHHHHHHHH	49.22	23236377
91	Phosphorylation	NRDLRKASVTIQARA CCHHHHHHHEHHHHH	23.87	-
106	Phosphorylation	EQEEEFISNTLFKKI HHHHHHHHHHHHHHH	29.14	28066266
108	Phosphorylation	EEEFISNTLFKKIQA HHHHHHHHHHHHHHH	27.12	28066266
120	Ubiquitination	IQALQKEKETLAVNY HHHHHHHHHHHCCCH	64.13	22790023
145	Ubiquitination	LSRKLMQLQHEKAEL HHHHHHHHHHHHHHH	3.32	27667366
166	Ubiquitination	EQEFQVNKLMKKIKK HHHHHHHHHHHHHHH	51.61	22790023
177	Ubiquitination	KIKKLENDTISKQLT HHHHHCCCHHHHHHC	35.72	27667366
184	Phosphorylation	DTISKQLTLEQLRRE CHHHHHHCHHHHHHH	26.25	29514104
227	Ubiquitination	EKRILQEKLDQPVSA HHHHHHHHCCCCCCC	44.39	27667366
233	Phosphorylation	EKLDQPVSAPPSPRD HHCCCCCCCCCCCCC	41.56	27087446
237	Phosphorylation	QPVSAPPSPRDISME CCCCCCCCCCCCCCC	31.35	27087446
242	Phosphorylation	PPSPRDISMEIDSPE CCCCCCCCCCCCCHH	18.04	26745281
247	Phosphorylation	DISMEIDSPENMMRH CCCCCCCCHHHHHHH	39.51	26745281
259	Ubiquitination	MRHIRFLKNEVERLK HHHHHHHHHHHHHHH	48.64	22790023
277	Phosphorylation	RAAQLQHSEKMAQYL HHHHHHHHHHHHHHH	26.42	-
316	Phosphorylation	EALCRQLSESESSLE HHHHHHHHHCCCCCC	30.64	25521595
318	Phosphorylation	LCRQLSESESSLEMD HHHHHHHCCCCCCCC	39.13	25521595
320	Phosphorylation	RQLSESESSLEMDDE HHHHHCCCCCCCCCH	49.88	25521595
321	Phosphorylation	QLSESESSLEMDDER HHHHCCCCCCCCCHH	25.05	21149613
329	Phosphorylation	LEMDDERYFNEMSAQ CCCCCHHHHHHHHHC	14.54	29899451
342	Phosphorylation	AQGLRPRTVSSPIPY HCCCCCCCCCCCCCC	27.67	21082442
344	Phosphorylation	GLRPRTVSSPIPYTP CCCCCCCCCCCCCCC	29.77	21082442
345	Phosphorylation	LRPRTVSSPIPYTPS CCCCCCCCCCCCCCC	23.63	22942356
349	Phosphorylation	TVSSPIPYTPSPSSS CCCCCCCCCCCCCCC	31.81	21659605
350	Phosphorylation	VSSPIPYTPSPSSSR CCCCCCCCCCCCCCC	16.37	25159016
352	Phosphorylation	SPIPYTPSPSSSRPI CCCCCCCCCCCCCCC	29.61	21082442
354	Phosphorylation	IPYTPSPSSSRPISP CCCCCCCCCCCCCCC	45.33	22942356
355	Phosphorylation	PYTPSPSSSRPISPG CCCCCCCCCCCCCCC	33.48	25159016
356	Phosphorylation	YTPSPSSSRPISPGL CCCCCCCCCCCCCCC	46.55	25159016
360	Phosphorylation	PSSSRPISPGLSYAS CCCCCCCCCCCCCCC	18.65	26824392
364	Phosphorylation	RPISPGLSYASHTVG CCCCCCCCCCCCCCC	25.27	21149613
365	Phosphorylation	PISPGLSYASHTVGF CCCCCCCCCCCCCCC	19.71	21149613
367	Phosphorylation	SPGLSYASHTVGFTP CCCCCCCCCCCCCCC	16.09	21149613
369	Phosphorylation	GLSYASHTVGFTPPT CCCCCCCCCCCCCCC	21.59	21149613
373	Phosphorylation	ASHTVGFTPPTSLTR CCCCCCCCCCCCCCC	23.56	21082442
376	Phosphorylation	TVGFTPPTSLTRAGM CCCCCCCCCCCCCCC	37.26	21149613
377	Phosphorylation	VGFTPPTSLTRAGMS CCCCCCCCCCCCCCH	33.25	21149613
379	Phosphorylation	FTPPTSLTRAGMSYY CCCCCCCCCCCCHHC	20.45	21149613
380	Methylation	TPPTSLTRAGMSYYN CCCCCCCCCCCHHCC	34.14	24129315
386	Phosphorylation	TRAGMSYYNSPGLHV CCCCCHHCCCCCEEE	11.23	28507225
388	Phosphorylation	AGMSYYNSPGLHVQH CCCHHCCCCCEEEEE	12.29	-
399	Phosphorylation	HVQHMGASHGITRPS EEEECCCCCCCCCCC	19.27	26643407
403	Phosphorylation	MGASHGITRPSPRRS CCCCCCCCCCCCCCC	40.91	26643407
406	Phosphorylation	SHGITRPSPRRSSSP CCCCCCCCCCCCCCC	27.96	26643407
410	Phosphorylation	TRPSPRRSSSPDKFK CCCCCCCCCCCCCCC	36.13	25159016
411	Phosphorylation	RPSPRRSSSPDKFKR CCCCCCCCCCCCCCC	44.04	25159016
412	Phosphorylation	PSPRRSSSPDKFKRP CCCCCCCCCCCCCCC	38.06	28507225
420	Phosphorylation	PDKFKRPTPPPSPNT CCCCCCCCCCCCCCC	53.08	19060867
424	Phosphorylation	KRPTPPPSPNTQSPV CCCCCCCCCCCCCCC	36.23	29514104
427	Phosphorylation	TPPPSPNTQSPVQPP CCCCCCCCCCCCCCC	33.53	25338131
429	Phosphorylation	PPSPNTQSPVQPPPP CCCCCCCCCCCCCCC	25.62	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCDC6_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCDC6_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCDC6_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CCDC6_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.