CCD96_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCD96_HUMAN
• UniProt AC: Q2M329
• Protein Name: Coiled-coil domain-containing protein 96
• Gene Name: CCDC96
• Organism: Homo sapiens (Human).
• Sequence Length: 555
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome .
• Protein Sequence: MDVSSEHTKDPGGEGGDGESLAARPSKIKASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLYGRDEFEDLEWSEEVQKLQEQQLRSDLLDQYRSLLVERNRSQRYNLYLQHKIFEALRRKKGLEAAEVADRGAEAEAPEKEQAYLRHLGMLEELKKQQADDLQWYHQELGQLKRQCQEKLTRVEKEWRRFQALKKQVVMQAMGSCRMRGGRQAALREVEQIQALEDKKEKEMSAVRLENIQLKQSLVHFETRMRTQEDLTQGLLLIDFEQLKIENQTFNEKIEERNEELLKLRSKVTNSVQVITHVKEKLHFMDMENACKKTQLAEIEAQAALGRDILTKTKQAREGLRTDNIRLNQKCGLLGKDSLLRDLEEKVDKTELLHRRLESLKRHHASLTLSCRGVRQKIREAKAFLPS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	GEGGDGESLAARPSK CCCCCCCCCCCCCCC	28.92	-
26	Phosphorylation	ESLAARPSKIKASSG CCCCCCCCCCCCCCC	41.27	25693802
32	Phosphorylation	PSKIKASSGPPTSPE CCCCCCCCCCCCCCC	61.24	-
143	Phosphorylation	KEVRFQASLPLTRID CCEEEEEECCCCCCC	21.53	25693802
147	Phosphorylation	FQASLPLTRIDEEEA EEEECCCCCCCHHHH	24.52	25693802
162	Phosphorylation	AAAPEAETERVEGEE HHCCHHHHHHCCCCH	35.82	25159151
199	Ubiquitination	AKSQEEGKRLYGRDE CCCHHHHHCCCCCHH	42.37	32142685
280	Ubiquitination	AEAEAPEKEQAYLRH CCCCCCHHHHHHHHH	54.81	29967540
296	Ubiquitination	GMLEELKKQQADDLQ HHHHHHHHHHHCHHH	61.33	-
313	Ubiquitination	HQELGQLKRQCQEKL HHHHHHHHHHHHHHH	32.32	29967540
373	Phosphorylation	DKKEKEMSAVRLENI HHHHHHHCCHHHHHH	25.38	26074081
385	Phosphorylation	ENIQLKQSLVHFETR HHHHHHHHHHHHHHC	30.67	26074081
391	Phosphorylation	QSLVHFETRMRTQED HHHHHHHHCCCCHHH	28.90	26074081
395	Phosphorylation	HFETRMRTQEDLTQG HHHHCCCCHHHHHCC	27.28	26074081
431	Ubiquitination	ERNEELLKLRSKVTN HHHHHHHHHHHHHCC	55.25	-
461	Ubiquitination	DMENACKKTQLAEIE CHHHHHCHHHHHHHH	41.19	29967540
498	Ubiquitination	DNIRLNQKCGLLGKD CCCHHHHHHCCCCCH	29.24	29967540
506	Phosphorylation	CGLLGKDSLLRDLEE HCCCCCHHHHHHHHH	32.56	24719451
514	Ubiquitination	LLRDLEEKVDKTELL HHHHHHHHCCHHHHH	46.49	29967540

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCD96_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCD96_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCD96_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CCD96_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.