CCD92_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCD92_MOUSE
• UniProt AC: Q8VDN4
• Protein Name: Coiled-coil domain-containing protein 92
• Gene Name: Ccdc92
• Organism: Mus musculus (Mouse).
• Sequence Length: 314
• Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole.
• Protein Sequence: MAATNLENQLHSAQKNLLFLQREHASTLKGLHAEIRRLQQHCTDLTYELTLKSFELTGDSSSRTTELKRRCEELEAQLKAKEEENRKLLQELEQKNAAIAVLENTVREREKKYLEELKVKSHKLSMLSGELEQRASTVAYLTSQLHAAKKKLLSSSGTSDASPAGSPALASYKPTPPKDKLPETPRRRMKKSLSAPLHPEFEEVYRFGAESRKLLLREPVDAMPDPTPFLLARESAEVQLKERPLVIPPIASDRSATGQHSPARDKPHKTHVGVAHRIHHATPSQAQPEGEMRAVDQVNASKVVRKHSGTDRTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
113	Phosphorylation	VREREKKYLEELKVK HHHHHHHHHHHHHHH	30.34	-
154	Phosphorylation	AAKKKLLSSSGTSDA HHHHHHHCCCCCCCC	32.66	29899451
155	Phosphorylation	AKKKLLSSSGTSDAS HHHHHHCCCCCCCCC	32.53	29899451
158	Phosphorylation	KLLSSSGTSDASPAG HHHCCCCCCCCCCCC	25.94	25293948
159	Phosphorylation	LLSSSGTSDASPAGS HHCCCCCCCCCCCCC	34.40	25293948
162	Phosphorylation	SSGTSDASPAGSPAL CCCCCCCCCCCCCHH	21.92	25293948
166	Phosphorylation	SDASPAGSPALASYK CCCCCCCCCHHHCCC	14.76	25293948
172	Phosphorylation	GSPALASYKPTPPKD CCCHHHCCCCCCCCC	18.51	29899451
173	Acetylation	SPALASYKPTPPKDK CCHHHCCCCCCCCCC	39.66	7718645
184	Phosphorylation	PKDKLPETPRRRMKK CCCCCCCCHHHHHHH	21.84	25521595
192	Phosphorylation	PRRRMKKSLSAPLHP HHHHHHHHHCCCCCH	23.26	24925903
194	Phosphorylation	RRMKKSLSAPLHPEF HHHHHHHCCCCCHHH	34.63	25521595
255	Phosphorylation	PPIASDRSATGQHSP CCCCCCCCCCCCCCC	34.86	28066266
257	Phosphorylation	IASDRSATGQHSPAR CCCCCCCCCCCCCCC	38.32	28066266
261	Phosphorylation	RSATGQHSPARDKPH CCCCCCCCCCCCCCC	16.62	21454597
308	Phosphorylation	SKVVRKHSGTDRTV- HHHHHHCCCCCCCC-	46.56	23375375
310	Phosphorylation	VVRKHSGTDRTV--- HHHHCCCCCCCC---	25.89	22324799

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCD92_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCD92_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCD92_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CCD92_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Qualitative and quantitative analyses of protein phosphorylation innaive and stimulated mouse synaptosomal preparations.";
Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F.,Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D.,Gerrits B., Panse C., Schlapbach R., Mansuy I.M.;
Mol. Cell. Proteomics 6:283-293(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-194, AND MASSSPECTROMETRY.
PubMed: 17114649