dbPTM

CCD63_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CCD63_MOUSE
UniProt AC	Q8CDV6
Protein Name	Coiled-coil domain-containing protein 63 {ECO:0000312\|MGI:MGI:3607777}
Gene Name	Ccdc63 {ECO:0000312\|MGI:MGI:3607777}
Organism	Mus musculus (Mouse).
Sequence Length	558
Subcellular Localization
Protein Description	Plays a role in spermiogenesis. [PubMed: 26501274 Involved in the elongation of flagella and the formation of sperm heads]
Protein Sequence	MKKVRRKGSSGLSELSEKAREQLAQAELRKLRQQFRKMVDSRKSFNFRHQRMIAGQYKEIETLKAEQAETTMLLSLVKSPKNLDINQKNFMELRFLLQTKGDYEALISSMKVLLGELDDKIVQMERKITNQRQLFLRTQEANNPKRLQRQIHVLESRLNLVTVHFDTMLTSNSQLRKEIEDLLFEKAAYDHVYQQLQRRLQTQKKTMNVAIEQSAQAYEQRVEAMARMAAMKDRQQKDISQYNLEIRELERLYDHETKLKSFLLAKLNDRSEFEDQAKKQEDVKSKKLGKKGKGESFASYEVAHLRLLKLAENGDLNQLTEDFLAKEEKNFARFTYVTELNNDMETMHKKTQRIQDDIINLRSQQQTSHEGTRSILKQMEEKLRKTTQEADIYETKYKEMSKTLEYLKNSVEKMFKKINCDATEILGKLGESGKVTDINLQQYFAIIEKKTNDLLLLESFRRLQEAEGPDVDVPQPFVNPFWGGSALLKPPEPIRVVLPVFGADSFSDKLEEVDSPLDHSTLQQMVLENFLQRERTKELQDTMSEKGDEIRLKKKVIG

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	KKVRRKGSSGLSELS CCHHCCCCCCHHHHH	25.03	-
10	Phosphorylation	KVRRKGSSGLSELSE CHHCCCCCCHHHHHH	53.04	-
384	Methylation	KQMEEKLRKTTQEAD HHHHHHHHHHHHHHH	45.39	-
401	Phosphorylation	ETKYKEMSKTLEYLK HHHHHHHHHHHHHHH	24.47	23649490
403	Phosphorylation	KYKEMSKTLEYLKNS HHHHHHHHHHHHHHH	19.95	23649490
459	Phosphorylation	NDLLLLESFRRLQEA CCHHHHHHHHHHHHH	24.83	28576409

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CCD63_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CCD63_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CCD63_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of CCD63_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CCD63_MOUSE

Related Literatures of Post-Translational Modification