CC85A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC85A_HUMAN
• UniProt AC: Q96PX6
• Protein Name: Coiled-coil domain-containing protein 85A
• Gene Name: CCDC85A
• Organism: Homo sapiens (Human).
• Sequence Length: 553
• Protein Sequence: MSKAAGGAAAAAAAAESCSPAPAGSSAAPPAPVEDLSKVSDEELLQWSKEELIRSLRRAEAEKVSAMLDHSNLIREVNRRLQLHLGEIRGLKDINQKLQEDNQELRDLCCFLDDDRQKGKRVSREWQRLGRYTAGVMHKEVALYLQKLKDLEVKQEEVVKENMELKELCVLLDEEKGAGCAGSRCSIDSQASLCQLTASTAPYVRDVGDGSSTSSTGSTDSPDHHKHHASSGSPEHLQKPRSEGSPEHSKHRSASPEHPQKPRACGTPDRPKALKGPSPEHHKPLCKGSPEQQRHPHPGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPRARGTSPEHLKQHYGGSPDHKHGGGSGGSGGSGGGSREGTLRRQAQEDGSPHHRNVYSGMNESTLSYVRQLEARVRQLEEENRMLPQASQNRRQPPTRNSSNMEKGWGSRARRVLQWWQGCRGIGRCLPTLPGSFRLSSGADGSNSSPNSAASFSGHATPSQQPEPVVHSLKVVWRKLGDAAGSCPGIRQHLSGNQYKGPM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Phosphorylation	AAAAAAESCSPAPAG HHHHHHHHCCCCCCC	18.37	26434552
25	Phosphorylation	CSPAPAGSSAAPPAP CCCCCCCCCCCCCCC	20.93	26471730
26	Phosphorylation	SPAPAGSSAAPPAPV CCCCCCCCCCCCCCH	27.77	26471730
37	Phosphorylation	PAPVEDLSKVSDEEL CCCHHHHHCCCHHHH	43.25	26434552
230	Phosphorylation	DHHKHHASSGSPEHL CCCCCCCCCCCHHHH	30.76	28348404
231	Phosphorylation	HHKHHASSGSPEHLQ CCCCCCCCCCHHHHC	44.04	28348404
233	Phosphorylation	KHHASSGSPEHLQKP CCCCCCCCHHHHCCC	29.12	28348404
242	Phosphorylation	EHLQKPRSEGSPEHS HHHCCCCCCCCCCCC	55.63	26699800
245	Phosphorylation	QKPRSEGSPEHSKHR CCCCCCCCCCCCCCC	24.06	26699800
249	Phosphorylation	SEGSPEHSKHRSASP CCCCCCCCCCCCCCC	28.61	24850871
253	Phosphorylation	PEHSKHRSASPEHPQ CCCCCCCCCCCCCCC	32.58	26437602
255	Phosphorylation	HSKHRSASPEHPQKP CCCCCCCCCCCCCCC	31.87	23403867
289	Phosphorylation	HKPLCKGSPEQQRHP CCCCCCCCHHHHCCC	15.68	20363803
300	Phosphorylation	QRHPHPGSSPETLPK HCCCCCCCCCCHHCH	47.36	20363803
301	Phosphorylation	RHPHPGSSPETLPKH CCCCCCCCCCHHCHH	32.44	23403867
304	Phosphorylation	HPGSSPETLPKHVLS CCCCCCCHHCHHHHC	52.31	27732954
311	Phosphorylation	TLPKHVLSGSPEHFQ HHCHHHHCCCHHHHH	35.82	23403867
313	Phosphorylation	PKHVLSGSPEHFQKH CHHHHCCCHHHHHHH	24.60	23403867
335	Phosphorylation	HARHSGGSPEHLQKH HHHHCCCCHHHHHHH	30.55	24719451
347	Phosphorylation	QKHALGGSLEHLPRA HHHHHCCCHHHCCCC	28.87	22617229
357	Phosphorylation	HLPRARGTSPEHLKQ HCCCCCCCCHHHHHH	35.24	23403867
358	Phosphorylation	LPRARGTSPEHLKQH CCCCCCCCHHHHHHH	30.99	23403867
366	Phosphorylation	PEHLKQHYGGSPDHK HHHHHHHHCCCCCCC	22.23	29978859
369	Phosphorylation	LKQHYGGSPDHKHGG HHHHHCCCCCCCCCC	23.85	28348404
381	Phosphorylation	HGGGSGGSGGSGGGS CCCCCCCCCCCCCCC	43.43	30242111
384	Phosphorylation	GSGGSGGSGGGSREG CCCCCCCCCCCCCCC	37.48	24719451
388	Phosphorylation	SGGSGGGSREGTLRR CCCCCCCCCCCHHHH	30.36	30242111
416	Phosphorylation	YSGMNESTLSYVRQL CCCCCHHHHHHHHHH	17.34	24260401
419	Phosphorylation	MNESTLSYVRQLEAR CCHHHHHHHHHHHHH	11.63	24260401
441	Phosphorylation	NRMLPQASQNRRQPP HCCCCHHHHCCCCCC	23.81	-
452	Phosphorylation	RQPPTRNSSNMEKGW CCCCCCCCCCCCCCC	21.57	29083192
453	Phosphorylation	QPPTRNSSNMEKGWG CCCCCCCCCCCCCCC	43.68	29083192
461	Phosphorylation	NMEKGWGSRARRVLQ CCCCCCCHHHHHHHH	19.09	29083192
490	Phosphorylation	LPGSFRLSSGADGSN CCCCEECCCCCCCCC	23.59	28111955
491	Phosphorylation	PGSFRLSSGADGSNS CCCEECCCCCCCCCC	42.46	28111955
496	Phosphorylation	LSSGADGSNSSPNSA CCCCCCCCCCCCCCC	33.80	28111955
498	Phosphorylation	SGADGSNSSPNSAAS CCCCCCCCCCCCCCH	49.20	28111955
499	Phosphorylation	GADGSNSSPNSAASF CCCCCCCCCCCCCHH	32.14	28111955
502	Phosphorylation	GSNSSPNSAASFSGH CCCCCCCCCCHHCCC	28.70	28111955
505	Phosphorylation	SSPNSAASFSGHATP CCCCCCCHHCCCCCC	21.47	28111955
507	Phosphorylation	PNSAASFSGHATPSQ CCCCCHHCCCCCCCC	27.46	28111955
511	Phosphorylation	ASFSGHATPSQQPEP CHHCCCCCCCCCCCC	20.14	28111955
513	Phosphorylation	FSGHATPSQQPEPVV HCCCCCCCCCCCCCE	36.77	28111955
522	Phosphorylation	QPEPVVHSLKVVWRK CCCCCEEEHHHHHHH	20.48	28111955
541	Methylation	AGSCPGIRQHLSGNQ HCCCCCHHHHHCCCC	24.63	-
541	Asymmetric dimethylarginine	AGSCPGIRQHLSGNQ HCCCCCHHHHHCCCC	24.63	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC85A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC85A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC85A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CC85A_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.