CC74A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC74A_HUMAN
• UniProt AC: Q96AQ1
• Protein Name: Coiled-coil domain-containing protein 74A
• Gene Name: CCDC74A
• Organism: Homo sapiens (Human).
• Sequence Length: 378
• Protein Sequence: MSGAGVAAGTRPPSSPTPGSRRRRQRPSVGVQSLRPQSPQLRQSDPQKRNLDLEKSLQFLQQQHSEMLAKLHEEIEHLKRENKDLHYKLIMNQTSQKKDGPSGNHLSRASAPLGARWVCINGVWVEPGGPSPARLKEGSSRTHRPGGKRGRLAGGSADTVRSPADSLSMSSFQSVKSISNSGKARPQPGSFNKQDSKADVSQKADLEEEPLLHNSKLDKVPGVQGQARKEKAEASNAGAACMGNSQHQGRQMGAGAHPPMILPLPLRKPTTLRQCEVLIRELWNTNLLQTQELRHLKSLLEGSQRPQAAPEEASFPRDQEATHFPKVSTKSLSKKCLSPPVAERAILPALKQTPKNNFAERQKRLQAMQKRRLHRSVL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSGAGVAAG ------CCCCCCCCC	37.03	26552605
2	O-linked_Glycosylation	------MSGAGVAAG ------CCCCCCCCC	37.03	30379171
10	Phosphorylation	GAGVAAGTRPPSSPT CCCCCCCCCCCCCCC	34.96	30108239
14	Phosphorylation	AAGTRPPSSPTPGSR CCCCCCCCCCCCCCC	52.19	26552605
15	Phosphorylation	AGTRPPSSPTPGSRR CCCCCCCCCCCCCCC	38.27	30108239
17	Phosphorylation	TRPPSSPTPGSRRRR CCCCCCCCCCCCCCC	42.08	30108239
20	Phosphorylation	PSSPTPGSRRRRQRP CCCCCCCCCCCCCCC	24.66	27251275
33	Phosphorylation	RPSVGVQSLRPQSPQ CCCCCHHHCCCCCCC	24.76	27080861
38	Phosphorylation	VQSLRPQSPQLRQSD HHHCCCCCCCHHCCC	19.80	24719451
87	Phosphorylation	RENKDLHYKLIMNQT HHCHHHHHHHHHCCC	18.13	-
95	Phosphorylation	KLIMNQTSQKKDGPS HHHHCCCCCCCCCCC	30.18	-
102	Phosphorylation	SQKKDGPSGNHLSRA CCCCCCCCCCCCCCC	58.73	-
107	Phosphorylation	GPSGNHLSRASAPLG CCCCCCCCCCCCCCC	20.46	-
235	Phosphorylation	RKEKAEASNAGAACM HHHHHHHCHHCCCCC	20.79	24114839
263	Phosphorylation	AHPPMILPLPLRKPT CCCCEEECCCCCCCC	22.47	27251275
314	Phosphorylation	QAAPEEASFPRDQEA CCCCCHHCCCCCHHH	38.78	26552605
322	Phosphorylation	FPRDQEATHFPKVST CCCCHHHHCCCCCCC	24.25	26552605
328	Phosphorylation	ATHFPKVSTKSLSKK HHCCCCCCCHHHHHH	35.92	26434776
329	Phosphorylation	THFPKVSTKSLSKKC HCCCCCCCHHHHHHH	27.86	26434776
331	Phosphorylation	FPKVSTKSLSKKCLS CCCCCCHHHHHHHCC	37.65	26434776
338	Phosphorylation	SLSKKCLSPPVAERA HHHHHHCCCHHHHHH	36.31	27966365

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC74A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC74A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC74A_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	23455924

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.