CC191_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC191_HUMAN
• UniProt AC: Q8NCU4
• Protein Name: Coiled-coil domain-containing protein 191
• Gene Name: CCDC191
• Organism: Homo sapiens (Human).
• Sequence Length: 936
• Protein Sequence: MLLAPQGRSFSKKRMGLNRWKRFTRKPSPKPTFGPDSVEHWIKRVEKASEFAVSNAFFTRNSDLPRSPWGQITDLKTSEQIEDHDEIYAEAQELVNDWLDTKLKQELASEEEGDAKNTVSSVTIMPEANGHLKYDKFDDLCGYLEEEEESTTVQKFIDHLLHKNVVDSAMMEDLGRKENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKKRKALEAKKEEEEIQREMVKLRREIIERRRTVKAAWKIEKKRQEENSQNSSEKVMFQSTHILPDEEKMVKERKRKLKEVLIQTFKENQQCQKRYFAAWHKLILDHRIKLGKAGTLSDWKIQLKVLRAWRDYTRFQKLERETQALENDLREENRKQQLATEYNRKQVLRHCFTEWQHWHGAELLKRELALTKEETRKKMDALLQAASLGKLSANGLSGISLPEEATAMVGPPVKNGQETAVPPLWEKPPLGSSGCMLSPPLGRTTTGNLQGSLQNVSLSAPGNKQHKTLGAEPSQQPGSNETLRTTSQKAEPLCLGHFHNRHVFQQQLIEKQKKKLQEQQKTILELKKNLQLAEAQWAAEHALAVTEAQSHLLSKPREEEPRTCQMLVNSPVASPGTEGRSDSRNSLSGLRRKPKQLMTPHPILKAMEERAIQRAECRRILAEKKKKQEEEKLAQLKAQEEERQKREAEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVLLRKKGLEPWKRLRMQSKQNIQVAEEHYSLFLQRKYMLTWFQRSQESLARKMAQADQFYSQILLKRVIQSWLQYVIDLQEEVRKFCVHFLQKKIFRAWFNMVREVKIDSQGKHEIAAEHSDRRILWITLRTWKKFVKFMKEERVKEERRQQLRRKVVEILPDFQVPGRYHELYQQSDTWSLSKTSLVNE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	LLAPQGRSFSKKRMG CCCCCCCCCCHHHHC		24719451
62	Phosphorylation	NAFFTRNSDLPRSPW CCCCCCCCCCCCCCC		-
67	Phosphorylation	RNSDLPRSPWGQITD CCCCCCCCCCCCCCC		24719451
109	Phosphorylation	KLKQELASEEEGDAK HHHHHHHCCCCCCCC		28450419
168	Phosphorylation	LHKNVVDSAMMEDLG HHHCHHCHHHHHHHC		-
177	Acetylation	MMEDLGRKENQDKKQ HHHHHCCCCCCCHHH		90723
182	Acetylation	GRKENQDKKQQKDPR CCCCCCCHHHHCCHH		90725
191	Phosphorylation	QQKDPRLTMEMRHKQ HHCCHHHHHHHHHHH		-
389	Ubiquitination	DLREENRKQQLATEY HHHHHHHHHHHHHHH		29967540
425	Phosphorylation	LKRELALTKEETRKK HHHHHHCCHHHHHHH		-
429	Phosphorylation	LALTKEETRKKMDAL HHCCHHHHHHHHHHH		-
506	Phosphorylation	TTGNLQGSLQNVSLS CCCCCCCCEEEEEEC		28348404
611	Methylation	SHLLSKPREEEPRTC HHHHCCCCCCCCCCC		-
624	Phosphorylation	TCQMLVNSPVASPGT CCHHHHCCCCCCCCC		24719451
628	Phosphorylation	LVNSPVASPGTEGRS HHCCCCCCCCCCCCC		28348404
640	Phosphorylation	GRSDSRNSLSGLRRK CCCCCCCCCCCCCCC		24719451
642	Phosphorylation	SDSRNSLSGLRRKPK CCCCCCCCCCCCCHH		24719451
664	Ubiquitination	ILKAMEERAIQRAEC HHHHHHHHHHHHHHH		30230243
673	Ubiquitination	IQRAECRRILAEKKK HHHHHHHHHHHHHHH		30230243
686	Ubiquitination	KKKQEEEKLAQLKAQ HHHHHHHHHHHHHHH		30230243
751	Acetylation	YERVLLRKKGLEPWK HHHHHHHHCCCCHHH		26051181
752	Acetylation	ERVLLRKKGLEPWKR HHHHHHHCCCCHHHH		26051181
758	Acetylation	KKGLEPWKRLRMQSK HCCCCHHHHHHHHHH		26051181
867	Phosphorylation	HEIAAEHSDRRILWI CHHHHCCCCCCCHHH		-
892	Ubiquitination	FMKEERVKEERRQQL HHHHHHHHHHHHHHH		-
902	Ubiquitination	RRQQLRRKVVEILPD HHHHHHHHHHHHCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC191_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC191_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC191_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of CC191_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.