CC177_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CC177_MOUSE
• UniProt AC: Q3UHB8
• Protein Name: Coiled-coil domain-containing protein 177
• Gene Name: Ccdc177
• Organism: Mus musculus (Mouse).
• Sequence Length: 706
• Protein Sequence: MVDPVPEEEKEGAEPGGSEGDEATASEPPDAQGAQQPAASSASASAAAPRKAEVPCGAEGGRREQSPLLHLDLFNFACPEAEGSRYVLTSPRSLEACARCAVKPVELLPRALADLVREAPGRSMRVATGLYEAYEAERLAKLQQCRAERERIMREEKRRLFTPKGPAAAPASASASASASALSGGSSSSCSSSSSLPASPASRVARRTSPSPPARSRPPPAGSRTGRKSHSLDSLSRRRDGALSSESGASSSSYSGESLRELRWPPRASARNSCPAGSASSAPNPLGRPSALALVPLTARSFSLGDLSHSPQTAQHVERIVRQVRAERGLRGVPERDRKIAALMLARHQEERLLLEQRAAAHGQWEQQRVRAEQRREREEREKQRALERGRRAWAAQVEERRGRRGREEREAARRRQQQCERSEERRRELAERQGLLRRERVERAARDDRLRKLQQEQNLKQREEGRQEGRERAELVRRERAQRAARARERQEGQLQREKRELSRAERARHEALLRGRVRQQQEEREGLRSSLEASLGRAQENYEQLQEQRARELRERARREELQGRRAKEAAERKEREHQAHLEALARAGERRLQHAAQVAEEAVQQKARRVVQTRLEKERAQRANKEKVERDEDCRRRELLQAIGRKLERSEQLSRERRSALESARSTARASFHVREKVREETNTRSFDRMVREAQLHASLDRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	EGAEPGGSEGDEATA CCCCCCCCCCCCCCC		29899451
66	Phosphorylation	EGGRREQSPLLHLDL CCCCCCCCCCEEEEE		20415495
78	S-palmitoylation	LDLFNFACPEAEGSR EEECCCCCCCCCCCC		28680068
86	Phosphorylation	PEAEGSRYVLTSPRS CCCCCCCEEECCHHH		29899451
89	Phosphorylation	EGSRYVLTSPRSLEA CCCCEEECCHHHHHH		22324799
90	Phosphorylation	GSRYVLTSPRSLEAC CCCEEECCHHHHHHH		22324799
123	Phosphorylation	VREAPGRSMRVATGL HHHCCCCCHHHHHHH		29899451
208	Phosphorylation	ASRVARRTSPSPPAR HHHCHHCCCCCCCHH		25521595
209	Phosphorylation	SRVARRTSPSPPARS HHCHHCCCCCCCHHC		25521595
211	Phosphorylation	VARRTSPSPPARSRP CHHCCCCCCCHHCCC		25521595
229	Phosphorylation	GSRTGRKSHSLDSLS CCCCCCCCCCHHHHH		22324799
231	Phosphorylation	RTGRKSHSLDSLSRR CCCCCCCCHHHHHHC		25521595
234	Phosphorylation	RKSHSLDSLSRRRDG CCCCCHHHHHHCCCC		22324799
236	Phosphorylation	SHSLDSLSRRRDGAL CCCHHHHHHCCCCCC		29899451
245	Phosphorylation	RRDGALSSESGASSS CCCCCCCCCCCCCCC		29899451
247	Phosphorylation	DGALSSESGASSSSY CCCCCCCCCCCCCCC		29899451
250	Phosphorylation	LSSESGASSSSYSGE CCCCCCCCCCCCCCC		29899451
254	Phosphorylation	SGASSSSYSGESLRE CCCCCCCCCCCCHHH		29899451
255	Phosphorylation	GASSSSYSGESLREL CCCCCCCCCCCHHHC		29899451
258	Phosphorylation	SSSYSGESLRELRWP CCCCCCCCHHHCCCC		29899451
269	Phosphorylation	LRWPPRASARNSCPA CCCCCCCHHCCCCCC		29899451
273	Phosphorylation	PRASARNSCPAGSAS CCCHHCCCCCCCCCC		20415495
278	Phosphorylation	RNSCPAGSASSAPNP CCCCCCCCCCCCCCC		29899451
280	Phosphorylation	SCPAGSASSAPNPLG CCCCCCCCCCCCCCC		20415495
281	Phosphorylation	CPAGSASSAPNPLGR CCCCCCCCCCCCCCC		20415495
301	Phosphorylation	LVPLTARSFSLGDLS HHHCCCCCCCCCCCC		25521595
303	Phosphorylation	PLTARSFSLGDLSHS HCCCCCCCCCCCCCC		18388127
308	Phosphorylation	SFSLGDLSHSPQTAQ CCCCCCCCCCHHHHH		29899451
310	Phosphorylation	SLGDLSHSPQTAQHV CCCCCCCCHHHHHHH		18388127
313	Phosphorylation	DLSHSPQTAQHVERI CCCCCHHHHHHHHHH		30372032
423	Phosphorylation	RQQQCERSEERRREL HHHHHHHHHHHHHHH		29899451
669	Phosphorylation	SALESARSTARASFH HHHHHHHHHHHHHHH		29899451
674	Phosphorylation	ARSTARASFHVREKV HHHHHHHHHHHHHHH		29899451
702	Phosphorylation	REAQLHASLDRK--- HHHHHHHHHCCC---		29899451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CC177_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CC177_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CC177_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of CC177_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.