| UniProt ID | CC174_HUMAN | |
|---|---|---|
| UniProt AC | Q6PII3 | |
| Protein Name | Coiled-coil domain-containing protein 174 | |
| Gene Name | CCDC174 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 467 | |
| Subcellular Localization | Nucleus . In the nucleus of neuroblastoma cells, it colocalizes with EIF4A3, a component of exon junction complex. | |
| Protein Description | Probably involved in neuronal development.. | |
| Protein Sequence | MDRRKKPLDVTASSLVDLKAELFRKQEEFKQEKLLKDSGVFGKPKTTNKKPSIWSKQNVGVSNRAEKDAEQKIEEQKTLDKAREKLEEKAKLYEKMTKGDFIDEEVEDMYLVDFTQKIIDKRKEMEASGAHRDSQKAGERDDDEENLPEGEIPPPQDPSEEWVDYVDSLGRSRRCMRKDLPDLLEMDKNLQGRLFISPANEKTLLSEDMRKELQRQQWEEEEREALKRPMGPVHYEDIRENEARQLGVGYFAFARDKELRNKQMKTLEMLREQTTDQRTKRENIKEKRKAILEARLAKLRQKKMKKSKEGGTEEENRDGDVIGPLPPEPEAVPTPRPAAQSSKVEVIVQERKDTKPGVPHIREWDRGKEFSFGYWSKRQSDLRAERDPEFAPPSDYFVGQKRTGFSSSQAWSRPGPAQSDPGQCPDQSHGPSPEHTSPTPAPDNPPQAPTVTFKTLDDMISYYKQVT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 14 | Phosphorylation | PLDVTASSLVDLKAE CCCCCHHHHHHHHHH | 26546556 | ||
| 38 | Phosphorylation | QEKLLKDSGVFGKPK HHHHHHHCCCCCCCC | - | ||
| 43 | Acetylation | KDSGVFGKPKTTNKK HHCCCCCCCCCCCCC | 25953088 | ||
| 197 | Phosphorylation | LQGRLFISPANEKTL CCCCEEECCCCHHHH | 30266825 | ||
| 235 | Phosphorylation | RPMGPVHYEDIRENE CCCCCCCHHHHHHHH | 28796482 | ||
| 266 | Phosphorylation | LRNKQMKTLEMLREQ HHHHHHHHHHHHHHH | 22210691 | ||
| 274 | Phosphorylation | LEMLREQTTDQRTKR HHHHHHHCCCHHHHH | 22210691 | ||
| 279 | Phosphorylation | EQTTDQRTKRENIKE HHCCCHHHHHHHHHH | - | ||
| 334 | Phosphorylation | PEPEAVPTPRPAAQS CCCCCCCCCCCCCCC | - | ||
| 371 | Phosphorylation | WDRGKEFSFGYWSKR CCCCCCEECCCCCHH | 28348404 | ||
| 380 | Phosphorylation | GYWSKRQSDLRAERD CCCCHHHHHHHCCCC | 22210691 | ||
| 401 | Ubiquitination | SDYFVGQKRTGFSSS HHCCCCCCCCCCCCC | - | ||
| 419 | Phosphorylation | SRPGPAQSDPGQCPD CCCCCCCCCCCCCCC | 28111955 | ||
| 428 | Phosphorylation | PGQCPDQSHGPSPEH CCCCCCCCCCCCCCC | 23401153 | ||
| 432 | Phosphorylation | PDQSHGPSPEHTSPT CCCCCCCCCCCCCCC | 25850435 | ||
| 436 | Phosphorylation | HGPSPEHTSPTPAPD CCCCCCCCCCCCCCC | 25850435 | ||
| 437 | Phosphorylation | GPSPEHTSPTPAPDN CCCCCCCCCCCCCCC | 25850435 | ||
| 439 | Phosphorylation | SPEHTSPTPAPDNPP CCCCCCCCCCCCCCC | 25850435 | ||
| 450 | Phosphorylation | DNPPQAPTVTFKTLD CCCCCCCEEEEEEHH | 28111955 | ||
| 452 | Phosphorylation | PPQAPTVTFKTLDDM CCCCCEEEEEEHHHH | 28111955 | ||
| 462 | Phosphorylation | TLDDMISYYKQVT-- EHHHHHHHHHHCC-- | - | ||
| 463 | Phosphorylation | LDDMISYYKQVT--- HHHHHHHHHHCC--- | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CC174_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CC174_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CC174_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of CC174_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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