CC171_HUMAN - dbPTM
CC171_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CC171_HUMAN
UniProt AC Q6TFL3
Protein Name Coiled-coil domain-containing protein 171
Gene Name CCDC171
Organism Homo sapiens (Human).
Sequence Length 1326
Subcellular Localization
Protein Description
Protein Sequence MNLNTSSNTGDTQRLKIASLDVKQILKNETELDITDNLRKKLHWAKKEKLEITTKHNAELASYESQIAKLRSEVEKGEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQTSQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMESHIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQTSELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQVEKASQAEAVADLEIIKNEFKEVESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDIEEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELESILDSFTVSGQWTSGIHKDKDKPPSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNIKELQDKLADVNKELSHLHTKCADREALISTLKVELQNVLHCWEKEKAQAAQSESELQKLSQAFHKDAEEKLTFLHTLYQHLVAGCVLIKQPEGMLDKFSWSELCAVLQENVDALIADLNRANEKIRHLEYICKNKSDTMRELQQTQEDTFTKVAEQIKAQESCWHRQKKELELQYSELFLEVQKRAQKFQEIAEKNMEKLNHIEKSHEQLVLENSHFKKLLSQTQREQMSLLAACALMAGALYPLYSRSCALSTQRDFLQEQVNTFELFKLEIRTLAQALSTVEEKKQEEAKMKKKTFKGLIRIFRKGVIAVLAANRLKILGQSCASLFTWMESFKEGIGMLVCTGEPQDKHKFPKHQKEQLRCLQALSWLTSSDLLAAIISSMAELQDVIGKADPNSRICGHLLIGAAKNSFAKLMDKISLVMECIPLHSSRSITYVEKDSLVQRLAHGLHKVNTLALKYGLRGHVPITKSTASLQKQILGFTQRLHAAEVERRSLRLEVTEFKRSVNEMKKELDKAQGLQMQLNEFKQSKLITHEKFESACEELNNALLREEQAQMLLNEQAQQLQELNYKLELHSSEEADKNQTLGEAVKSLSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEENIHDAESALRMAAKDKECVANHMRAVENTLHKVRDQISLSWSAASRNDFTLQLPKLHLETFAMEGLKGGPEVVACQAMIKSFMDVYQLASTRIMTLEKEMTSHRSHIAALKSELHTACLRENASLQSIGSRDHSNLSIPSRAPLPADTTGIGDFLPLKAELDTTYTFLKETFINTVPHALTSSHSSPVTMSANANRPTQIGL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
5Phosphorylation---MNLNTSSNTGDT
---CCCCCCCCCCCC		36.3824043423
6Phosphorylation--MNLNTSSNTGDTQ
--CCCCCCCCCCCCC		22.1024043423
7Phosphorylation-MNLNTSSNTGDTQR
-CCCCCCCCCCCCCC		36.0524043423
9PhosphorylationNLNTSSNTGDTQRLK
CCCCCCCCCCCCCEE		38.0824043423
12PhosphorylationTSSNTGDTQRLKIAS
CCCCCCCCCCEEEEE		19.5519053533
23AcetylationKIASLDVKQILKNET
EEEECCHHHHHCCCC		31.1525953088
53PhosphorylationKKEKLEITTKHNAEL
HHHHCEEEHHHHHHH		22.0324719451
54PhosphorylationKEKLEITTKHNAELA
HHHCEEEHHHHHHHH		35.6520873877
62PhosphorylationKHNAELASYESQIAK
HHHHHHHHHHHHHHH		41.9020873877
63PhosphorylationHNAELASYESQIAKL
HHHHHHHHHHHHHHH		17.6220873877
65PhosphorylationAELASYESQIAKLRS
HHHHHHHHHHHHHHH		20.7520873877
69UbiquitinationSYESQIAKLRSEVEK
HHHHHHHHHHHHHHH		46.1729967540
76UbiquitinationKLRSEVEKGEALRQS
HHHHHHHHHHHHHHH		68.1929967540
83PhosphorylationKGEALRQSLEYDLAV
HHHHHHHHHHHHHHH		19.4126437602
115UbiquitinationEAHRIQEKLCAQNSE
HHHHHHHHHHHCCHH		32.2729967540
115 (in isoform 4)Ubiquitination-32.27-
140UbiquitinationAFQTSQQKWKEECRR
HHHHHHHHHHHHHHH		53.2329967540
166PhosphorylationIQNCNREYDLLMKEK
HHHCHHHHHHHHHHH		14.51-
186UbiquitinationTLQEALEKHQREKNE
HHHHHHHHHHHHHHH		45.98-
186 (in isoform 4)Ubiquitination-45.98-
196PhosphorylationREKNEMESHIRETAL
HHHHHHHHHHHHHHH		23.93-
276PhosphorylationLRKEFEATTLRVRKL
HHHHHHHHHHHHHHH		21.1124247654
333UbiquitinationVADLEIIKNEFKEVE
HHCHHHHHHHHHHHH		56.9629967540
356UbiquitinationNAQESFAKLNLLEKE
HHHHHHHHHHHHHHH		35.5829967540
362 (in isoform 4)Ubiquitination-58.65-
362UbiquitinationAKLNLLEKEYFSKNK
HHHHHHHHHHHHCCC		58.65-
407UbiquitinationQEELVMAKKHQAFLV
HHHHHHHHHHHHHHH		32.46-
416PhosphorylationHQAFLVETCENNVKE
HHHHHHHHHCCCHHH		20.0326074081
452PhosphorylationKDKPPSFSVVLERLR
CCCCCCHHHHHHHHH		18.6922468782
461PhosphorylationVLERLRRTLTDYQNK
HHHHHHHHHHHHHHH		27.8122461510
463PhosphorylationERLRRTLTDYQNKLE
HHHHHHHHHHHHHHH		31.8622461510
465PhosphorylationLRRTLTDYQNKLEDA
HHHHHHHHHHHHHHC		14.5722461510
491PhosphorylationSTKQKIDSHTKNIKE
HHHHHHHHHHHCHHH		36.21-
540UbiquitinationNVLHCWEKEKAQAAQ
HHHHHHHHHHHHHHH		39.7629967540
548 (in isoform 4)Ubiquitination-38.06-
550 (in isoform 4)Ubiquitination-49.18-
629UbiquitinationRHLEYICKNKSDTMR
HHHHHHHCCCCHHHH		58.8329967540
648UbiquitinationTQEDTFTKVAEQIKA
HHHHHHHHHHHHHHH		34.9429967540
654UbiquitinationTKVAEQIKAQESCWH
HHHHHHHHHHHCHHH		43.65-
656 (in isoform 4)Ubiquitination-37.83-
662 (in isoform 4)Ubiquitination-26.05-
671PhosphorylationKKELELQYSELFLEV
HHHHHHHHHHHHHHH		19.4125690035
701UbiquitinationEKLNHIEKSHEQLVL
HHHHHHHHHHHHHHH		57.4129967540
739PhosphorylationALMAGALYPLYSRSC
HHHHHCHHHHHCCHH		7.23-
742PhosphorylationAGALYPLYSRSCALS
HHCHHHHHCCHHHHH		9.49-
743PhosphorylationGALYPLYSRSCALST
HCHHHHHCCHHHHHH		25.9624719451
771PhosphorylationLFKLEIRTLAQALST
HHHHHHHHHHHHHHH		31.91-
777PhosphorylationRTLAQALSTVEEKKQ
HHHHHHHHHHHHHHH		33.16-
778PhosphorylationTLAQALSTVEEKKQE
HHHHHHHHHHHHHHH		32.55-
930PhosphorylationIPLHSSRSITYVEKD
CCCCCCCCEEEECHH		22.6424043423
932PhosphorylationLHSSRSITYVEKDSL
CCCCCCEEEECHHHH		23.8224043423
933PhosphorylationHSSRSITYVEKDSLV
CCCCCEEEECHHHHH		12.6324043423
936UbiquitinationRSITYVEKDSLVQRL
CCEEEECHHHHHHHH		42.4429967540
944 (in isoform 4)Ubiquitination-9.26-
952PhosphorylationHGLHKVNTLALKYGL
HHHHHHHHHHHHHCC		19.1824719451
956UbiquitinationKVNTLALKYGLRGHV
HHHHHHHHHCCCCCC		31.50-
957PhosphorylationVNTLALKYGLRGHVP
HHHHHHHHCCCCCCC		23.4224719451
964 (in isoform 4)Ubiquitination-23.90-
966PhosphorylationLRGHVPITKSTASLQ
CCCCCCCCCCHHHHH		16.93-
967UbiquitinationRGHVPITKSTASLQK
CCCCCCCCCHHHHHH		46.6729967540
1025UbiquitinationQMQLNEFKQSKLITH
HHHHHHHHHHHCCCH		47.7029967540
1034UbiquitinationSKLITHEKFESACEE
HHCCCHHHHHHHHHH		46.9929967540
1089UbiquitinationQTLGEAVKSLSEAKM
CHHHHHHHHHHHHHH		53.3729967540
1092PhosphorylationGEAVKSLSEAKMELR
HHHHHHHHHHHHHHH		42.4727251275
1095UbiquitinationVKSLSEAKMELRRKD
HHHHHHHHHHHHHHH		28.9329967540
1119UbiquitinationLTQLEQDKRRLEENI
HHHHHHHHHHHHHHH		38.8329967540
1140UbiquitinationLRMAAKDKECVANHM
HHHHHHCHHHHHHHH		52.9129967540
1156UbiquitinationAVENTLHKVRDQISL
HHHHHHHHHHHHHCC		41.92-
1164 (in isoform 4)Ubiquitination-16.52-
1214PhosphorylationMDVYQLASTRIMTLE
HHHHHHHHHHHHHHH		27.15-
1215PhosphorylationDVYQLASTRIMTLEK
HHHHHHHHHHHHHHH		20.71-
1235UbiquitinationRSHIAALKSELHTAC
HHHHHHHHHHHHHHH		36.8429967540
1315PhosphorylationHSSPVTMSANANRPT
CCCCCEECCCCCCCC		14.70-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CC171_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CC171_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CC171_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of CC171_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CC171_HUMAN

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Related Literatures of Post-Translational Modification

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